Reacquisition of nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee host

Cell Host and Microbe

Volumn 12, Issue 3, 2012, Pages 373-380

  Götz, Nicola ^a   Sauter, Daniel ^a   Usmani, Shariq M ^a   Fritz, Joëlle V ^b   Goffinet, Christine ^a   Heigele, Anke ^a   Geyer, Matthias ^c   Bibollet Ruche, Frederic ^d   Learn, Gerald H ^d   Fackler, Oliver T ^b   Hahn, Beatrice H ^d   Kirchhoff, Frank ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; NEF PROTEIN; PROTEIN; TETHERIN PROTEIN; UNCLASSIFIED DRUG; VPU PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMPANZEE; GENE FUNCTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VIVO STUDY; LENTIVIRINAE; NONHUMAN; PRIORITY JOURNAL; VIRUS RELEASE;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, CD; DISEASE MODELS, ANIMAL; HIV-1; HUMAN IMMUNODEFICIENCY VIRUS PROTEINS; HUMANS; MUTANT PROTEINS; MUTATION, MISSENSE; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PAN TROGLODYTES; PRIMATE DISEASES; VIRAL REGULATORY AND ACCESSORY PROTEINS; VIRULENCE FACTORS;

HUMAN IMMUNODEFICIENCY VIRUS 1; PAN; PRIMATES; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 84866412071     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2012.07.008     Document Type: Article

References (29)

1. E. Bailes, F. Gao, F. Bibollet-Ruche, V. Courgnaud, M. Peeters, P.A. Marx, B.H. Hahn, and P.M. Sharp Hybrid origin of SIV in chimpanzees Science 300 2003 1713
2. P.N. Fultz, A. Srinivasan, C.R. Greene, D. Butler, R.B. Swenson, and H.M. McClure Superinfection of a chimpanzee with a second strain of human immunodeficiency virus J. Virol. 61 1987 4026 4029
3. F.A. Horenkamp, S. Breuer, A. Schulte, S. Lülf, M. Weyand, K. Saksela, and M. Geyer Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly Traffic 12 2011 867 877
4. S. Jäger, P. Cimermancic, N. Gulbahce, J.R. Johnson, K.E. McGovern, S.C. Clarke, M. Shales, G. Mercenne, L. Pache, and K. Li Global landscape of HIV-human protein complexes Nature 481 2012 365 370
5. B. Jia, R. Serra-Moreno, W. Neidermyer, A. Rahmberg, J. Mackey, I.B. Fofana, W.E. Johnson, S. Westmoreland, and D.T. Evans Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2 PLoS Pathog. 5 2009 e1000429
6. F. Kirchhoff Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses Cell Host Microbe 8 2010 55 67
7. F. Kirchhoff, M. Schindler, A. Specht, N. Arhel, and J. Münch Role of Nef in primate lentiviral immunopathogenesis Cell. Mol. Life Sci. 65 2008 2621 2636
8. B.T. Korber, B.T. Foley, C.L. Kuiken, S.K. Pillai, and J.K. Sodroski Numbering positions in HIV relative to HXB2CG B. Korber, C.L. Kuiken, B. Foley, B. Hahn, F. McCutchan, J.W. Mellors, J. Sodroski, Human Retroviruses and AIDS 1998: A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences 1998 Los Alamos National Laboratory Los Alamos, NM 102 111
9. B. Korber, M. Muldoon, J. Theiler, F. Gao, R. Gupta, A. Lapedes, B.H. Hahn, S. Wolinsky, and T. Bhattacharya Timing the ancestor of the HIV-1 pandemic strains Science 288 2000 1789 1796
10. N. Laguette, and M. Benkirane How SAMHD1 changes our view of viral restriction Trends Immunol. 33 2012 26 33
11. R.A. Liberatore, and P.D. Bieniasz Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo Proc. Natl. Acad. Sci. USA 108 2011 18097 18101
12. E.S. Lim, H.S. Malik, and M. Emerman Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses J. Virol. 84 2010 7124 7134
13. M.H. Malim, and M. Emerman HIV-1 accessory proteins - ensuring viral survival in a hostile environment Cell Host Microbe 3 2008 388 398
14. M.W. McNatt, T. Zang, T. Hatziioannou, M. Bartlett, I.B. Fofana, W.E. Johnson, S.J.D. Neil, and P.D. Bieniasz Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants PLoS Pathog. 5 2009 e1000300
15. N.R. Meyerson, and S.L. Sawyer Two-stepping through time: mammals and viruses Trends Microbiol. 19 2011 286 294
16. D.M. Mwaengo, and F.J. Novembre Molecular cloning and characterization of viruses isolated from chimpanzees with pathogenic human immunodeficiency virus type 1 infections J. Virol. 72 1998 8976 8987
17. F.J. Novembre, M. Saucier, D.C. Anderson, S.A. Klumpp, S.P. O'Neil, C.R. Brown 2nd, C.E. Hart, P.C. Guenthner, R.B. Swenson, and H.M. McClure Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1 J. Virol. 71 1997 4086 4091
18. F.J. Novembre, J. de Rosayro, S. Nidtha, S.P. O'Neil, T.R. Gibson, T. Evans-Strickfaden, C.E. Hart, and H.M. McClure Rapid CD4(+) T-cell loss induced by human immunodeficiency virus type 1(NC) in uninfected and previously infected chimpanzees J. Virol. 75 2001 1533 1539
19. S.P. O'Neil, F.J. Novembre, A.B. Hill, C. Suwyn, C.E. Hart, T. Evans-Strickfaden, D.C. Anderson, J. deRosayro, J.G. Herndon, M. Saucier, and H.M. McClure Progressive infection in a subset of HIV-1-positive chimpanzees J. Infect. Dis. 182 2000 1051 1062
20. V. Planelles, and E. Barker Roles of Vpr and Vpx in modulating the virus-host cell relationship Mol. Aspects Med. 31 2010 398 406
21. D. Sauter, M. Schindler, A. Specht, W.N. Landford, J. Münch, K.-A. Kim, J. Votteler, U. Schubert, F. Bibollet-Ruche, and B.F. Keele Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains Cell Host Microbe 6 2009 409 421
22. D. Sauter, S. Hué, S.J. Petit, J.-C. Plantier, G.J. Towers, F. Kirchhoff, and R.K. Gupta HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef Retrovirology 8 2011 103
23. R. Serra-Moreno, B. Jia, M. Breed, X. Alvarez, and D.T. Evans Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/BST-2 in a pathogenic nef-deleted SIV Cell Host Microbe 9 2011 46 57
24. M. Skasko, Y. Wang, Y. Tian, A. Tokarev, J. Munguia, A. Ruiz, E.B. Stephens, S.J. Opella, and J. Guatelli HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions J. Biol. Chem. 287 2012 58 67
25. A. Specht, A. Telenti, R. Martinez, J. Fellay, E. Bailes, D.T. Evans, M. Carrington, B.H. Hahn, D.B. Goldstein, and F. Kirchhoff Counteraction of HLA-C-mediated immune control of HIV-1 by Nef J. Virol. 84 2010 7300 7311
26. R. Vigan, and S.J. Neil Determinants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein J. Virol 84 2010 12958 12970
27. M. Worobey, M. Gemmel, D.E. Teuwen, T. Haselkorn, K. Kunstman, M. Bunce, J.-J. Muyembe, J.-M.M. Kabongo, R.M. Kalengayi, and E. Van Marck Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960 Nature 455 2008 661 664
28. S.J. Yang, L.A. Lopez, C.M. Exline, K.G. Haworth, and P.M. Cannon Lack of adaptation to human tetherin in HIV-1 group O and P Retrovirology 8 2011 78
29. F. Zhang, S.J. Wilson, W.C. Landford, B. Virgen, D. Gregory, M.C. Johnson, J. Munch, F. Kirchhoff, P.D. Bieniasz, and T. Hatziioannou Nef proteins from simian immunodeficiency viruses are tetherin antagonists Cell Host Microbe 6 2009 54 67