Placebo-induced analgesia in an operant pain model in rats

Pain

Volumn 153, Issue 10, 2012, Pages 2009-2016

  Nolan, Todd A ^a   Price, Donald D ^b   Caudle, Robert M ^b   Murphy, Niall P ^c   Neubert, John K ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Analgesia; Morphine; Operant; Opioid; Placebo; Preclinical

Indexed keywords

MORPHINE SULFATE; NALOXONE; PLACEBO;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; FACE PAIN; MALE; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN ASSESSMENT; PLACEBO EFFECT; PLACEBO INDUCED ANALGESIA; PRIORITY JOURNAL; RAT; THERMAL INJURY; THERMAL STIMULATION; TREATMENT RESPONSE;

ANALGESICS, OPIOID; ANIMALS; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; HUMANS; MALE; MORPHINE; PAIN; PLACEBO EFFECT; RATS; RATS, HAIRLESS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME;

EID: 84866411816     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2012.04.026     Document Type: Article

References (65)

1. R. Ader Conditioned immunomodulation: research needs and directions Brain Behav Immun 17 2003 S51 57
2. M. Amanzio, and F. Benedetti Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems vs conditioning-activated specific subsystems J Neurosci 19 1999 484 494
3. F. Benedetti The opposite effects of the opiate antagonist naloxone and the cholecystokinin antagonist proglumide on placebo analgesia PAIN® 64 1996 535 543
4. F. Benedetti Placebo analgesia Neurol Sci 27 2006 S100 102
5. F. Benedetti Mechanisms of placebo and placebo-related effects across diseases and treatments Ann Rev Pharmacol Toxicol 48 2008 33 60
6. F. Benedetti No prefrontal control, no placebo response PAIN® 148 2010 357 358
7. F. Benedetti, M. Amanzio, R. Rosato, and C. Blanchard Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors Nat Med 17 2011 1228 1230
8. F. Benedetti, H.S. Mayberg, T.D. Wager, C.S. Stohler, and J.K. Zubieta Neurobiological mechanisms of the placebo effect J Neurosci 25 2005 10390 10402
9. F. Benedetti, A. Pollo, L. Lopiano, M. Lanotte, S. Vighetti, and I. Rainero Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses J Neurosci 23 2003 4315 4323
10. U. Bingel, J. Lorenz, E. Schoell, C. Weiller, and C. Buchel Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network PAIN® 120 2006 8 15
11. C.D. Bryant, K.W. Roberts, C.S. Culbertson, A. Le, C.J. Evans, and M.S. Fanselow Pavlovian conditioning of multiple opioid-like responses in mice Drug Alcohol Depend 103 2009 74 83
12. E. Carlino, A. Pollo, and F. Benedetti Placebo analgesia and beyond: a melting pot of concepts and ideas for neuroscience Curr Opin Anaesthesiol 24 2011 540 544
13. L. Colloca, and F. Benedetti Placebos and painkillers: is mind as real as matter? Nat Rev Neurosci 6 2005 545 552
14. L. Colloca, and F. Benedetti Placebo analgesia induced by social observational learning PAIN® 144 2009 28 34
15. A. Contarino, R. Picetti, H.W. Matthes, G.F. Koob, B.L. Kieffer, and L.H. Gold Lack of reward and locomotor stimulation induced by heroin in mu-opioid receptor-deficient mice Eur J Pharmacol 446 2002 103 109
16. R.M. Craft, J.L. Clark, S.P. Hart, and M.K. Pinckney Sex differences in locomotor effects of morphine in the rat Pharmacol Biochem Behav 85 2006 850 858
17. R. de la Fuente-Fernandez, T.J. Ruth, V. Sossi, M. Schulzer, D.B. Calne, and A.J. Stoessl Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease Science 293 2001 1164 1166
18. N.J. Diederich, and C.G. Goetz The placebo treatments in neurosciences: new insights from clinical and neuroimaging studies Neurology 71 2008 677 684
19. A.J. Dinnerstein, M. Lowenthal, and B. Blitz The interaction of drugs with placebos in the control of pain and anxiety Perspect Biol Med 10 1966 103 117
20. J. Dum, and A. Herz Endorphinergic modulation of neural reward systems indicated by behavioral changes Pharmacol Biochem Behav 21 1984 259 266
21. F. Eippert, U. Bingel, E.D. Schoell, J. Yacubian, R. Klinger, J. Lorenz, and C. Buchel Activation of the opioidergic descending pain control system underlies placebo analgesia Neuron 63 2009 533 543
22. P. Enck, F. Benedetti, and M. Schedlowski New insights into the placebo and nocebo responses Neuron 59 2008 195 206
23. D. Filliol, S. Ghozland, J. Chluba, M. Martin, H.W. Matthes, F. Simonin, K. Befort, C. Gaveriaux-Ruff, A. Dierich, M. LeMeur, O. Valverde, R. Maldonado, and B.L. Kieffer Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses Nat Genet 25 2000 195 200
24. H. Flor, N. Birbaumer, R. Schulz, S.M. Grusser, and R.F. Mucha Pavlovian conditioning of opioid and nonopioid pain inhibitory mechanisms in humans Eur J Pain 6 2002 395 402
25. E.L. Gardner Addiction and brain reward and antireward pathways Adv Psychosom Med 30 2011 22 60
26. D.W. Giang, A.D. Goodman, R.B. Schiffer, D.H. Mattson, M. Petrie, N. Cohen, and R. Ader Conditioning of cyclophosphamide-induced leukopenia in humans J Neuropsychiatry Clin Neurosci 8 1996 194 201
27. L.H. Gliedman, W.H. Gantt, and H.A. Teitelbaum Some implications of conditional reflex studies for placebo research Am J Psychiatry 113 1957 1103 1107
28. A.P. Goldstein Participant expectancies in psychotherapy Psychiatry 25 1962 72 79
29. J.Y. Guo, J.Y. Wang, and F. Luo Dissection of placebo analgesia in mice. The conditions for activation of opioid and non-opioid systems J Psychopharmacol 24 2010 1561 1567
30. A. Hecht, and E. Schiorring Behavioral effects of low and high acute doses of morphine in solitary mice Psychopharmacology 64 1979 73 79
31. R.J. Herrnstein Placebo effect in the rat Science 138 1962 677 678
32. J. Hunsley, and R. Westmacott Interpreting the magnitude of the placebo effect: mountain or Molehill? J Clin Psychol 63 2007 391 399
33. P.I. Johnson, J.R. Stellar, and A.D. Paul Regional reward differences within the ventral pallidum are revealed by microinjections of a mu opiate receptor agonist Neuropharmacology 32 1993 1305 1314
34. R. Klinger, S. Soost, H. Flor, and M. Worm Classical conditioning and expectancy in placebo hypoalgesia: a randomized controlled study in patients with atopic dermatitis and persons with healthy skin PAIN® 128 2007 31 39
35. E.B. Koshi, and C.A. Short Placebo theory and its implications for research and clinical practice. A review of the recent literature Pain Pract 7 2007 4 20
36. P. Krummenacher, V. Candia, G. Folkers, M. Schedlowski, and G. Schonbachler Prefrontal cortex modulates placebo analgesia PAIN® 148 2010 368 374
37. J. Le Merrer, J.A. Becker, K. Befort, and B.L. Kieffer Reward processing by the opioid system in the brain Physiol Rev 89 2009 1379 1412
38. J.D. Levine, N.C. Gordon, J.C. Bornstein, and H.L. Fields Role of pain in placebo analgesia Proc Natl Acad Sci USA 76 1979 3528 3531
39. J.D. Levine, N.C. Gordon, and H.L. Fields The mechanism of placebo analgesia Lancet 2 1978 654 657
40. J.D. Levine, N.C. Gordon, R. Smith, and H.L. Fields Analgesic responses to morphine and placebo in individuals with postoperative pain PAIN® 10 1981 379 389
41. H.W. Matthes, R. Maldonado, F. Simonin, O. Valverde, S. Slowe, I. Kitchen, K. Befort, A. Dierich, M. Le Meur, P. Dolle, E. Tzavara, J. Hanoune, B.P. Roques, and B.L. Kieffer Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene Nature 383 1996 819 823
42. H. Merskey The taxonomy of pain Med Clin North Am 91 2007 13 20 vii
43. J.E. Morley, A.S. Levine, G.K. Yim, and M.T. Lowy Opioid modulation of appetite Neurosci Biobehav Rev 7 1983 281 305
44. R.F. Mucha, and S.D. Iversen Increased food intake after opioid microinjections into nucleus accumbens and ventral tegmental area of rat Brain Res 397 1986 214 224
45. J.K. Neubert, C. King, W. Malphurs, F. Wong, J.P. Weaver, A.C. Jenkins, H.L. Rossi, and R.M. Caudle Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior Mol Pain 4 2008 43
46. J.K. Neubert, H.L. Rossi, W. Malphurs, C.J. Vierck Jr, and R.M. Caudle Differentiation between capsaicin-induced allodynia and hyperalgesia using a thermal operant assay Behav Brain Res 170 2006 308 315
47. J.K. Neubert, C.G. Widmer, W. Malphurs, H.L. Rossi, C.J. Vierck Jr, and R.M. Caudle Use of a novel thermal operant behavioral assay for characterization of orofacial pain sensitivity PAIN® 116 2005 386 395
48. T.A. Nolan, R.M. Caudle, and J.K. Neubert Effect of caloric and non-caloric sweet reward solutions on thermal facial operant conditioning Behav Brain Res 216 2011 723 725
49. K. Olness, and R. Ader Conditioning as an adjunct in the pharmacotherapy of lupus erythematosus J Dev Behav Pediatr 13 1992 124 125
50. A. Pollo, and F. Benedetti The placebo response: neurobiological and clinical issues of neurological relevance Prog Brain Res 175 2009 283 294
51. D.D. Price, J. Craggs, G.N. Verne, W.M. Perlstein, and M.E. Robinson Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients PAIN® 127 2007 63 72
52. D.D. Price, D.G. Finniss, and F. Benedetti A comprehensive review of the placebo effect: recent advances and current thought Ann Rev Psychol 59 2008 565 590
53. D.D. Price, L.S. Milling, I. Kirsch, A. Duff, G.H. Montgomery, and S.S. Nicholls An analysis of factors that contribute to the magnitude of placebo analgesia in an experimental paradigm PAIN® 83 1999 147 156
54. Y.H. Qiu, X.Y. Wu, H. Xu, and D. Sackett Neuroimaging study of placebo analgesia in humans Neurosci Bull 25 2009 277 282
55. T.E. Robinson, and K.C. Berridge Incentive-sensitization and addiction Addiction 96 2001 103 114
56. H.L. Rossi, C.J. Vierck Jr, R.M. Caudle, and J.K. Neubert Characterization of cold sensitivity and thermal preference using an operant orofacial assay Mol Pain 2 2006 37
57. R.D. Treede, D.R. Kenshalo, R.H. Gracely, and A.K. Jones The cortical representation of pain PAIN® 79 1999 105 111
58. F.C. Tulunay, I.H. Ayhan, and S.B. Sparber The effects of morphine and delta-9-tetrahydrocannabinol on motor activity in rats Psychopharmacology 78 1982 358 360
59. L.J. Vanderschuren, and R.C. Pierce Sensitization processes in drug addiction Curr Top Behav Neurosci 3 2010 179 195
60. L. Vase, J.L. Riley 3rd, and D.D. Price A comparison of placebo effects in clinical analgesic trials vs studies of placebo analgesia PAIN® 99 2002 443 452
61. N.D. Volkow, G.J. Wang, Y. Ma, J.S. Fowler, W. Zhu, L. Maynard, F. Telang, P. Vaska, Y.S. Ding, C. Wong, and J.M. Swanson Expectation enhances the regional brain metabolic and the reinforcing effects of stimulants in cocaine abusers J Neurosci 23 2003 11461 11468
62. T.D. Wager, J.K. Rilling, E.E. Smith, A. Sokolik, K.L. Casey, R.J. Davidson, S.M. Kosslyn, R.M. Rose, and J.D. Cohen Placebo-induced changes in FMRI in the anticipation and experience of pain Science 303 2004 1162 1167
63. A.Z. Weitemier, and N.P. Murphy Accumbal dopamine and serotonin activity throughout acquisition and expression of place conditioning: correlative relationships with preference and aversion Eur J Neurosci 29 2009 1015 1026
64. M. Zimmermann Ethical guidelines for investigations of experimental pain in conscious animals PAIN® 16 1983 109 110
65. J.K. Zubieta, and C.S. Stohler Neurobiological mechanisms of placebo responses Ann NY Acad Sci 1156 2009 198 210