-
1
-
-
84864913725
-
Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer
-
10.1186/bcr3229, 22812534
-
Cortez V, Mann M, Tekmal S, Suzuki T, Miyata N, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Vadlamudi RK. Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer. Breast Cancer Res 2012, 14:R108. 10.1186/bcr3229, 22812534.
-
(2012)
Breast Cancer Res
, vol.14
-
-
Cortez, V.1
Mann, M.2
Tekmal, S.3
Suzuki, T.4
Miyata, N.5
Rodriguez-Aguayo, C.6
Lopez-Berestein, G.7
Sood, A.K.8
Vadlamudi, R.K.9
-
2
-
-
81455131182
-
Gene symbol precision
-
10.1016/j.gene.2011.09.035, 22019431
-
Bennani-Baiti B, Bennani-Baiti IM. Gene symbol precision. Gene 2012, 491:103-109. 10.1016/j.gene.2011.09.035, 22019431.
-
(2012)
Gene
, vol.491
, pp. 103-109
-
-
Bennani-Baiti, B.1
Bennani-Baiti, I.M.2
-
3
-
-
38149045693
-
DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
-
10.1126/science.1147674, 18187655
-
Perillo B, Ombra MN, Bertoni A, Cuozzo C, Sacchetti S, Sasso A, Chiariotti L, Malorni A, Abbondanza C, Avvedimento EV. DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression. Science 2008, 319:202-206. 10.1126/science.1147674, 18187655.
-
(2008)
Science
, vol.319
, pp. 202-206
-
-
Perillo, B.1
Ombra, M.N.2
Bertoni, A.3
Cuozzo, C.4
Sacchetti, S.5
Sasso, A.6
Chiariotti, L.7
Malorni, A.8
Abbondanza, C.9
Avvedimento, E.V.10
-
4
-
-
47849101525
-
PELP1 - a novel estrogen receptor-interacting protein
-
10.1016/j.mce.2008.04.019, 2578818, 18571832
-
Brann DW, Zhang QG, Wang RM, Mahesh VB, Vadlamudi RK. PELP1 - a novel estrogen receptor-interacting protein. Mol Cell Endocrinol 2008, 290:2-7. 10.1016/j.mce.2008.04.019, 2578818, 18571832.
-
(2008)
Mol Cell Endocrinol
, vol.290
, pp. 2-7
-
-
Brann, D.W.1
Zhang, Q.G.2
Wang, R.M.3
Mahesh, V.B.4
Vadlamudi, R.K.5
-
5
-
-
77953121401
-
PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity
-
10.1038/embor.2010.62, 2892318, 20448663
-
Nair SS, Nair BC, Cortez V, Chakravarty D, Metzger E, Schule R, Brann DW, Tekmal RR, Vadlamudi RK. PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity. EMBO Rep 2010, 11:438-444. 10.1038/embor.2010.62, 2892318, 20448663.
-
(2010)
EMBO Rep
, vol.11
, pp. 438-444
-
-
Nair, S.S.1
Nair, B.C.2
Cortez, V.3
Chakravarty, D.4
Metzger, E.5
Schule, R.6
Brann, D.W.7
Tekmal, R.R.8
Vadlamudi, R.K.9
-
6
-
-
40849094564
-
Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells
-
2262166, 18079323
-
Rajhans R, Nair HB, Nair SS, Cortez V, Ikuko K, Kirma NB, Zhou D, Holden AE, Brann DW, Chen S, Tekmal RR, Vadlamudi RK. Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells. Mol Endocrinol 2008, 22:649-664. 2262166, 18079323.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 649-664
-
-
Rajhans, R.1
Nair, H.B.2
Nair, S.S.3
Cortez, V.4
Ikuko, K.5
Kirma, N.B.6
Zhou, D.7
Holden, A.E.8
Brann, D.W.9
Chen, S.10
Tekmal, R.R.11
Vadlamudi, R.K.12
-
7
-
-
33744933461
-
HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism
-
10.1158/0008-5472.CAN-05-4076, 16707480
-
Subbaramaiah K, Howe LR, Port ER, Brogi E, Fishman J, Liu CH, Hla T, Hudis C, Dannenberg AJ. HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism. Cancer Res 2006, 66:5504-5511. 10.1158/0008-5472.CAN-05-4076, 16707480.
-
(2006)
Cancer Res
, vol.66
, pp. 5504-5511
-
-
Subbaramaiah, K.1
Howe, L.R.2
Port, E.R.3
Brogi, E.4
Fishman, J.5
Liu, C.H.6
Hla, T.7
Hudis, C.8
Dannenberg, A.J.9
-
8
-
-
82455174447
-
Epigenetic and epigenomic mechanisms shape sarcoma and other mesenchymal tumor pathogenesis
-
10.2217/epi.11.93, 22126291
-
Bennani-Baiti IM. Epigenetic and epigenomic mechanisms shape sarcoma and other mesenchymal tumor pathogenesis. Epigenomics 2011, 3:715-732. 10.2217/epi.11.93, 22126291.
-
(2011)
Epigenomics
, vol.3
, pp. 715-732
-
-
Bennani-Baiti, I.M.1
-
9
-
-
84863987775
-
Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma
-
10.1016/j.humpath.2011.10.010, 22245111
-
Bennani-Baiti IM, Machado I, Llombart-Bosch A, Kovar H. Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma. Hum Pathol 2012, 43:1300-1307. 10.1016/j.humpath.2011.10.010, 22245111.
-
(2012)
Hum Pathol
, vol.43
, pp. 1300-1307
-
-
Bennani-Baiti, I.M.1
Machado, I.2
Llombart-Bosch, A.3
Kovar, H.4
-
10
-
-
72249117352
-
Identification of cell-active lysine specific demethylase 1-selective inhibitors
-
10.1021/ja907055q, 19950987
-
Ueda R, Suzuki T, Mino K, Tsumoto H, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N. Identification of cell-active lysine specific demethylase 1-selective inhibitors. J Am Chem Soc 2009, 131:17536-17537. 10.1021/ja907055q, 19950987.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 17536-17537
-
-
Ueda, R.1
Suzuki, T.2
Mino, K.3
Tsumoto, H.4
Nakagawa, H.5
Hasegawa, M.6
Sasaki, R.7
Mizukami, T.8
Miyata, N.9
-
11
-
-
10344251495
-
Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors
-
10.1210/jc.2004-0909, 1262662, 15579769
-
Vadlamudi RK, Balasenthil S, Broaddus RR, Gustafsson JA, Kumar R. Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors. J Clin Endocrinol Metab 2004, 89:6130-6138. 10.1210/jc.2004-0909, 1262662, 15579769.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 6130-6138
-
-
Vadlamudi, R.K.1
Balasenthil, S.2
Broaddus, R.R.3
Gustafsson, J.A.4
Kumar, R.5
-
12
-
-
79954624183
-
Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis
-
10.1158/1078-0432.CCR-10-2718, 21421858
-
Chakravarty D, Roy SS, Babu CR, Dandamudi R, Curiel TJ, Vivas-Mejia P, Lopez-Berestein G, Sood AK, Vadlamudi RK. Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis. Clin Cancer Res 2011, 17:2250-2259. 10.1158/1078-0432.CCR-10-2718, 21421858.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2250-2259
-
-
Chakravarty, D.1
Roy, S.S.2
Babu, C.R.3
Dandamudi, R.4
Curiel, T.J.5
Vivas-Mejia, P.6
Lopez-Berestein, G.7
Sood, A.K.8
Vadlamudi, R.K.9
-
13
-
-
84859153574
-
Central role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancer
-
10.1210/me.2011-1101, 22403175
-
Yang L, Ravindranathan P, Ramanan M, Kapur P, Hammes SR, Hsieh JT, Raj GV. Central role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancer. Mol Endocrinol 2012, 26:550-561. 10.1210/me.2011-1101, 22403175.
-
(2012)
Mol Endocrinol
, vol.26
, pp. 550-561
-
-
Yang, L.1
Ravindranathan, P.2
Ramanan, M.3
Kapur, P.4
Hammes, S.R.5
Hsieh, J.T.6
Raj, G.V.7
-
14
-
-
83055173059
-
Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis
-
10.1007/s11060-011-0637-y, 21735116
-
Kefalopoulou Z, Tzelepi V, Zolota V, Grivas PD, Christopoulos C, Kalofonos H, Maraziotis T, Sotiropoulou-Bonikou G. Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis. J Neurooncol 2012, 106:23-31. 10.1007/s11060-011-0637-y, 21735116.
-
(2012)
J Neurooncol
, vol.106
, pp. 23-31
-
-
Kefalopoulou, Z.1
Tzelepi, V.2
Zolota, V.3
Grivas, P.D.4
Christopoulos, C.5
Kalofonos, H.6
Maraziotis, T.7
Sotiropoulou-Bonikou, G.8
-
15
-
-
0029148429
-
Steroid hormone receptors in astrocytic neoplasms
-
discussion 503-494, 10.1227/00006123-199509000-00019, 7501116
-
Carroll RS, Zhang J, Dashner K, Sar M, Black PM. Steroid hormone receptors in astrocytic neoplasms. Neurosurgery 1995, 37:496-503. discussion 503-494, 10.1227/00006123-199509000-00019, 7501116.
-
(1995)
Neurosurgery
, vol.37
, pp. 496-503
-
-
Carroll, R.S.1
Zhang, J.2
Dashner, K.3
Sar, M.4
Black, P.M.5
-
16
-
-
33644515318
-
Estradiol modulation of astrocytic form and function: implications for hormonal control of synaptic communication
-
10.1016/j.neuroscience.2005.10.017, 16326016
-
Mong JA, Blutstein T. Estradiol modulation of astrocytic form and function: implications for hormonal control of synaptic communication. Neuroscience 2006, 138:967-975. 10.1016/j.neuroscience.2005.10.017, 16326016.
-
(2006)
Neuroscience
, vol.138
, pp. 967-975
-
-
Mong, J.A.1
Blutstein, T.2
-
17
-
-
80052743686
-
Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors
-
10.1093/neuonc/nor049, 3145466, 21653597
-
Singh MM, Manton CA, Bhat KP, Tsai WW, Aldape K, Barton MC, Chandra J. Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro Oncol 2011, 13:894-903. 10.1093/neuonc/nor049, 3145466, 21653597.
-
(2011)
Neuro Oncol
, vol.13
, pp. 894-903
-
-
Singh, M.M.1
Manton, C.A.2
Bhat, K.P.3
Tsai, W.W.4
Aldape, K.5
Barton, M.C.6
Chandra, J.7
-
18
-
-
84867091498
-
Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor
-
Willmann D, Lim S, Wetzel S, Metzger E, Jandausch A, Wilk W, Jung M, Forne I, Imhof A, Janzer A, Kirfel J, Waldmann H, Schüle R, Buettner R. Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. Int J Cancer 2012,
-
(2012)
Int J Cancer
-
-
Willmann, D.1
Lim, S.2
Wetzel, S.3
Metzger, E.4
Jandausch, A.5
Wilk, W.6
Jung, M.7
Forne, I.8
Imhof, A.9
Janzer, A.10
Kirfel, J.11
Waldmann, H.12
Schüle, R.13
Buettner, R.14
|