메뉴 건너뛰기




Volumn 14, Issue 5, 2012, Pages

Integration of ERα-PELP1-HER2 signaling by LSD1 (KDM1A/AOF2) offers combinatorial therapeutic opportunities to circumventing hormone resistance in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); BENZAMIDE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR ALPHA; EUTONYL TEN; HISTONE DEMETHYLASE; HISTONE H3; LETROZOLE; LOPAC P 8013; N [3 [3 (2 AMINOCYCLOPROPYL)PHENOXY] 1 (BENZYLCARBAMOYL)PROPYL]BENZAMIDE; PARGYLINE; PROTEIN LSD1; PROTEIN PELP1; SUPIRDYL; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANYLCYPROMINE; UNCLASSIFIED DRUG; COREPRESSOR PROTEIN;

EID: 84866406289     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3249     Document Type: Editorial
Times cited : (23)

References (18)
  • 2
    • 81455131182 scopus 로고    scopus 로고
    • Gene symbol precision
    • 10.1016/j.gene.2011.09.035, 22019431
    • Bennani-Baiti B, Bennani-Baiti IM. Gene symbol precision. Gene 2012, 491:103-109. 10.1016/j.gene.2011.09.035, 22019431.
    • (2012) Gene , vol.491 , pp. 103-109
    • Bennani-Baiti, B.1    Bennani-Baiti, I.M.2
  • 4
    • 47849101525 scopus 로고    scopus 로고
    • PELP1 - a novel estrogen receptor-interacting protein
    • 10.1016/j.mce.2008.04.019, 2578818, 18571832
    • Brann DW, Zhang QG, Wang RM, Mahesh VB, Vadlamudi RK. PELP1 - a novel estrogen receptor-interacting protein. Mol Cell Endocrinol 2008, 290:2-7. 10.1016/j.mce.2008.04.019, 2578818, 18571832.
    • (2008) Mol Cell Endocrinol , vol.290 , pp. 2-7
    • Brann, D.W.1    Zhang, Q.G.2    Wang, R.M.3    Mahesh, V.B.4    Vadlamudi, R.K.5
  • 5
    • 77953121401 scopus 로고    scopus 로고
    • PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity
    • 10.1038/embor.2010.62, 2892318, 20448663
    • Nair SS, Nair BC, Cortez V, Chakravarty D, Metzger E, Schule R, Brann DW, Tekmal RR, Vadlamudi RK. PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity. EMBO Rep 2010, 11:438-444. 10.1038/embor.2010.62, 2892318, 20448663.
    • (2010) EMBO Rep , vol.11 , pp. 438-444
    • Nair, S.S.1    Nair, B.C.2    Cortez, V.3    Chakravarty, D.4    Metzger, E.5    Schule, R.6    Brann, D.W.7    Tekmal, R.R.8    Vadlamudi, R.K.9
  • 6
    • 40849094564 scopus 로고    scopus 로고
    • Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells
    • 2262166, 18079323
    • Rajhans R, Nair HB, Nair SS, Cortez V, Ikuko K, Kirma NB, Zhou D, Holden AE, Brann DW, Chen S, Tekmal RR, Vadlamudi RK. Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells. Mol Endocrinol 2008, 22:649-664. 2262166, 18079323.
    • (2008) Mol Endocrinol , vol.22 , pp. 649-664
    • Rajhans, R.1    Nair, H.B.2    Nair, S.S.3    Cortez, V.4    Ikuko, K.5    Kirma, N.B.6    Zhou, D.7    Holden, A.E.8    Brann, D.W.9    Chen, S.10    Tekmal, R.R.11    Vadlamudi, R.K.12
  • 7
    • 33744933461 scopus 로고    scopus 로고
    • HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism
    • 10.1158/0008-5472.CAN-05-4076, 16707480
    • Subbaramaiah K, Howe LR, Port ER, Brogi E, Fishman J, Liu CH, Hla T, Hudis C, Dannenberg AJ. HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism. Cancer Res 2006, 66:5504-5511. 10.1158/0008-5472.CAN-05-4076, 16707480.
    • (2006) Cancer Res , vol.66 , pp. 5504-5511
    • Subbaramaiah, K.1    Howe, L.R.2    Port, E.R.3    Brogi, E.4    Fishman, J.5    Liu, C.H.6    Hla, T.7    Hudis, C.8    Dannenberg, A.J.9
  • 8
    • 82455174447 scopus 로고    scopus 로고
    • Epigenetic and epigenomic mechanisms shape sarcoma and other mesenchymal tumor pathogenesis
    • 10.2217/epi.11.93, 22126291
    • Bennani-Baiti IM. Epigenetic and epigenomic mechanisms shape sarcoma and other mesenchymal tumor pathogenesis. Epigenomics 2011, 3:715-732. 10.2217/epi.11.93, 22126291.
    • (2011) Epigenomics , vol.3 , pp. 715-732
    • Bennani-Baiti, I.M.1
  • 9
    • 84863987775 scopus 로고    scopus 로고
    • Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma
    • 10.1016/j.humpath.2011.10.010, 22245111
    • Bennani-Baiti IM, Machado I, Llombart-Bosch A, Kovar H. Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma. Hum Pathol 2012, 43:1300-1307. 10.1016/j.humpath.2011.10.010, 22245111.
    • (2012) Hum Pathol , vol.43 , pp. 1300-1307
    • Bennani-Baiti, I.M.1    Machado, I.2    Llombart-Bosch, A.3    Kovar, H.4
  • 11
    • 10344251495 scopus 로고    scopus 로고
    • Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors
    • 10.1210/jc.2004-0909, 1262662, 15579769
    • Vadlamudi RK, Balasenthil S, Broaddus RR, Gustafsson JA, Kumar R. Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors. J Clin Endocrinol Metab 2004, 89:6130-6138. 10.1210/jc.2004-0909, 1262662, 15579769.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6130-6138
    • Vadlamudi, R.K.1    Balasenthil, S.2    Broaddus, R.R.3    Gustafsson, J.A.4    Kumar, R.5
  • 13
    • 84859153574 scopus 로고    scopus 로고
    • Central role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancer
    • 10.1210/me.2011-1101, 22403175
    • Yang L, Ravindranathan P, Ramanan M, Kapur P, Hammes SR, Hsieh JT, Raj GV. Central role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancer. Mol Endocrinol 2012, 26:550-561. 10.1210/me.2011-1101, 22403175.
    • (2012) Mol Endocrinol , vol.26 , pp. 550-561
    • Yang, L.1    Ravindranathan, P.2    Ramanan, M.3    Kapur, P.4    Hammes, S.R.5    Hsieh, J.T.6    Raj, G.V.7
  • 14
    • 83055173059 scopus 로고    scopus 로고
    • Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis
    • 10.1007/s11060-011-0637-y, 21735116
    • Kefalopoulou Z, Tzelepi V, Zolota V, Grivas PD, Christopoulos C, Kalofonos H, Maraziotis T, Sotiropoulou-Bonikou G. Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis. J Neurooncol 2012, 106:23-31. 10.1007/s11060-011-0637-y, 21735116.
    • (2012) J Neurooncol , vol.106 , pp. 23-31
    • Kefalopoulou, Z.1    Tzelepi, V.2    Zolota, V.3    Grivas, P.D.4    Christopoulos, C.5    Kalofonos, H.6    Maraziotis, T.7    Sotiropoulou-Bonikou, G.8
  • 15
    • 0029148429 scopus 로고
    • Steroid hormone receptors in astrocytic neoplasms
    • discussion 503-494, 10.1227/00006123-199509000-00019, 7501116
    • Carroll RS, Zhang J, Dashner K, Sar M, Black PM. Steroid hormone receptors in astrocytic neoplasms. Neurosurgery 1995, 37:496-503. discussion 503-494, 10.1227/00006123-199509000-00019, 7501116.
    • (1995) Neurosurgery , vol.37 , pp. 496-503
    • Carroll, R.S.1    Zhang, J.2    Dashner, K.3    Sar, M.4    Black, P.M.5
  • 16
    • 33644515318 scopus 로고    scopus 로고
    • Estradiol modulation of astrocytic form and function: implications for hormonal control of synaptic communication
    • 10.1016/j.neuroscience.2005.10.017, 16326016
    • Mong JA, Blutstein T. Estradiol modulation of astrocytic form and function: implications for hormonal control of synaptic communication. Neuroscience 2006, 138:967-975. 10.1016/j.neuroscience.2005.10.017, 16326016.
    • (2006) Neuroscience , vol.138 , pp. 967-975
    • Mong, J.A.1    Blutstein, T.2
  • 17
    • 80052743686 scopus 로고    scopus 로고
    • Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors
    • 10.1093/neuonc/nor049, 3145466, 21653597
    • Singh MM, Manton CA, Bhat KP, Tsai WW, Aldape K, Barton MC, Chandra J. Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro Oncol 2011, 13:894-903. 10.1093/neuonc/nor049, 3145466, 21653597.
    • (2011) Neuro Oncol , vol.13 , pp. 894-903
    • Singh, M.M.1    Manton, C.A.2    Bhat, K.P.3    Tsai, W.W.4    Aldape, K.5    Barton, M.C.6    Chandra, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.