Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters

Biochemical and Biophysical Research Communications

Volumn 426, Issue 2, 2012, Pages 172-176

  de Boussac, Hugues ^a,b   Orbán, Tamás I ^a   Várady, György ^a   Tihanyi, Borbála ^a   Bacquet, Caroline ^a   Brózik, Anna ^a   Váradi, András ^a   Sarkadi, Balázs ^a   Arányi, Tamás ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b Faculté de Médecine   (France)

Author keywords

ABCG2 promoter variants; Aryl hydrocarbon receptor; BCRP; Hepatocellular carcinoma; Oxidative stress; Transcription

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; AROMATIC HYDROCARBON RECEPTOR; BREAST CANCER RESISTANCE PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL ESTER; SCATTER FACTOR;

ARTICLE; CELL MEMBRANE; CELL SURFACE; DRUG ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

ATP-BINDING CASSETTE TRANSPORTERS; CARCINOMA, HEPATOCELLULAR; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HEPATOCYTE GROWTH FACTOR; HUMANS; LIVER NEOPLASMS; MAP KINASE SIGNALING SYSTEM; NEOPLASM PROTEINS; OXIDATIVE STRESS; PHORBOL ESTERS; PHOSPHATIDYLINOSITOL 3-KINASES; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN; TRANSCRIPTION, GENETIC;

EID: 84866403217     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.08.046     Document Type: Article

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