The aryl hydrocarbon receptor antagonist, 3′methoxy-4′nitroflavone, attenuates 2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent regulation of growth factor signaling and apoptosis in the MCF-10A cell line

Toxicology and Applied Pharmacology

Volumn 188, Issue 1, 2003, Pages 42-49

  Davis II, John W ^a,b   Burdick, Andrew D ^a   Lauer, Fredine T ^a   Burchiel, Scott W ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Apoptosis; Aryl hydrocarbon receptor; Growth factor signaling; TCDD; Transforming growth factor ; Tumor promotion

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3' METHOXY 4' NITROFLAVONE; AROMATIC HYDROCARBON RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FLAVONE DERIVATIVE; GROWTH FACTOR; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ATTENUATION; BREAST EPITHELIUM; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0037381221     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(03)00012-7     Document Type: Article

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