Airway closure on imaging relates to airway hyperresponsiveness and peripheral airway disease in asthma

Journal of Applied Physiology

Volumn 113, Issue 6, 2012, Pages 958-966

  Farrow, Catherine E ^a,b   Salome, Cheryl M ^a,b,c   Harris, Benjamin E ^a,b,d   Bailey, Dale L ^b,d   Bailey, Elizabeth ^d   Berend, Norbert ^a,b,c   Young, Iven H ^e   King, Gregory G ^a,b,c,d  

^a WOOLCOCK INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c Cooperative Research Centre for Asthma and Airways ^*  (Australia)

^d ROYAL NORTH SHORE HOSPITAL   (Australia)

^e ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Airway closure; Airway hyperresponsiveness; Asthma; Single photon emission computed tomography; Ventilation heterogeneity

Indexed keywords

BRONCHOCONSTRICTING AGENT; DIAGNOSTIC AGENT; METHACHOLINE CHLORIDE;

ADULT; AGED; ARTICLE; ASTHMA; BIOLOGICAL MODEL; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER SIMULATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; INHALATION TEST; LUNG; LUNG VENTILATION; LUNG VOLUME; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PREDICTIVE VALUE; RADIOGRAPHY; SCINTISCANNING; SEVERITY OF ILLNESS INDEX; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPIROMETRY; STATISTICAL MODEL; VITAL CAPACITY;

ADULT; AGED; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; BRONCHOCONSTRICTION; BRONCHOCONSTRICTOR AGENTS; COMPUTER SIMULATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LINEAR MODELS; LUNG; LUNG VOLUME MEASUREMENTS; MALE; METHACHOLINE CHLORIDE; MIDDLE AGED; MODELS, BIOLOGICAL; PREDICTIVE VALUE OF TESTS; PULMONARY VENTILATION; SEVERITY OF ILLNESS INDEX; SPIROMETRY; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED; VITAL CAPACITY; YOUNG ADULT;

EID: 84866378538     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01618.2011     Document Type: Article

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