Prepro-thyrotropin releasing hormone 178-199 immunoreactivity is altered in the hypothalamus of the Wistar-Kyoto strain of rat

Brain Research

Volumn 913, Issue 2, 2001, Pages 224-233

  Suzuki, Shotaro ^a,b   Solberg, Leah C ^c   Redei, Eva E ^c   Handa, Robert J ^b  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Parastrial nucleus; Paraventricular nucleus; Prohormone convertase; Thyroid hormone releasing hormone; Wistar WKY

Indexed keywords

CORTICOTROPIN; FURIN; MESSENGER RNA; PREPROPROTIRELIN[178-199]; PROTEINASE; PROTIRELIN; UNCLASSIFIED DRUG;

ANXIETY; ARTICLE; BEHAVIOR; BRAIN REGION; CELL COUNT; COMPARATIVE STUDY; CONTROLLED STUDY; CORTICOTROPIN RELEASE; HORMONE SYNTHESIS; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEUROENDOCRINE DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; STRAIN DIFFERENCE;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ASPARTIC ENDOPEPTIDASES; AXONS; DEPRESSION; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNOHISTOCHEMISTRY; MALE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PEPTIDE FRAGMENTS; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASES; PROTEIN PRECURSORS; RATS; RATS, INBRED WKY; RATS, WISTAR; RNA, MESSENGER; STRESS; SUBTILISINS; THYROTROPIN-RELEASING HORMONE;

EID: 0035929515     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02853-0     Document Type: Article

References (53)

1. Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system?
2. Androgen inhibits the increases in hypothalamic corticotropin-releasing hormone (CRH) and CRH-immunoreactivity following gonadectomy
3. Physiological mapping of local inhibitory inputs to the hypothalamic paraventricular nucleus
4. Hypophysiotropic CRF neurons display a sustained immediate-early gene response to chronic stress but not to adrenalectomy
5. Processing of thyrotropin-releasing hormone prohormone (pro-TRH) generates pro-TRH-connecting peptides. Identification and characterization of prepro-TRH-(160-169) and prepro-TRH-(178-199) in the rat nervous system
6. A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry
7. Fos expression in forebrain afferents to the hypothalamic paraventricular nucleus following swim stress
8. Pattern and time course of immediate early gene expression in rat brain following acute stress
9. Projections of the sexually dimorphic anteroventral periventricular nucleus in the female rat
10. Estrogenic regulation of proenkephalin mRNA expression in the ventromedial hypothalamus of the adult male rat
11. Hormonal regulation of androgen receptor messenger RNA in the medial preoptic area of the male rat
12. Induction of c-fos mRNA in the brain and anterior pituitary gland by a novel environment
13. Antidepressants and hypothalamic-pituitary-adrenocortical regulation
14. Immunohistochemical localization in the rat brain of the precursor for thyrotropin-releasing hormone
15. Two activation states of the prohormone convertase PC1 in the secretory pathway
16. Regulation of stress-induced transcriptional changes in the hypothalamic neurosecretory neurons
17. Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons
18. Functional identification of central afferent projections conveying information of acute 'stress' to the hypothalamic paraventricular nucleus
19. Immunohistochemical localization of thyrotropin-releasing hormone in the rat hypothalamus and pituitary
20. Distribution of immunoreactive human growth hormone-like material and thyrotropin-releasing hormone in the rat central nervous system: Evidence for their coexistence in the same neurons
21. Immunolocalization of the thyrotropin-releasing hormone prohormone in the rat central nervous system
22. Immunocytochemical distribution of neurons containing a peptide derived from thyrotropin-releasing hormone precursor in the rat brain
23. The hypothalamic-pituitary-adrenal axis and the female reproductive system
24. Inhibition of stress-induced neuroendocrine and behavioral responses in the rat by prepro-thyrotropin-releasing hormone 178-199
25. Corticosteroid receptor function is decreased in depressed patients
26. Bed nucleus of the stria terminalis: Cytoarchitecture, immunohistochemistry, and projection to the parabrachial nucleus in the rat
27. PreproTRH(178-199) and two novel peptides (pFQ7 and pSE14) derived from its processing, which are produced in the paraventricular nucleus of the rat hypothalamus, are regulated during suckling
28. Pro-thyrotropin-releasing hormone processing by recombinant PC1
29. Identification of the thyrotropin-releasing hormone precursor, its processing products, and its coexpression with convertase 1 in primary cultures of hypothalamic neurons: Anatomic distribution of PC1 and PC2
30. Identification of the thyrotropin-releasing hormone-prohormone and its posttranslational processing in a transfected AtT20 tumoral cell line
31. Stress ulcer susceptibility and depression in Wistar Kyoto (WKY) rats
32. Passive-avoidance behavior in Wistar-Kyoto (WKY), Wistar, and Fischer-344 rats
33. Open field, learned helplessness, conditioned defensive burying, and forced-swim tests in WKY rats
34. Depressive behavior and stress ulcer in Wistar Kyoto rats
35. Sex differences and stress response of WKY rats
36. Differential coexpression of genes encoding prothyrotropin-releasing hormone (pro-TRH) and prohormone convertases (PC1 and PC2) in rat brain neurons: Implications for differential processing of pro-TRH
37. Sexual dimorphism in the neuropil of the preoptic area of the rat and its dependence on neonatal androgen
38. Corticotropin release inhibiting factor is encoded within prepro-TRH
39. Corticotropin release-inhibiting factor is preprothyrotropin-releasing hormone-(178-199)
40. Antidepressant-like properties of prepro-TRH 178-199: Acute effects in the forced swim test
41. Strain differences in hypothalamic-pituitary-adrenal activity and stress ulcer
42. Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat
43. The organization of forebrain afferents to the paraventricular and supraoptic nuclei of the rat
44. Gene expression of prohormone and proprotein convertases in the rat CNS: A comparative in situ hybridization analysis
45. Processing of prothyrotropin-releasing hormone by the family of prohormone convertases
46. Localization of thyrotropin-releasing hormone prohormone messenger ribonucleic acid in rat brain in situ hybridization
47. Projections of the medial preoptic nucleus: A Phaseolus vulgaris leucoagglutinin anterograde tract-tracing study in the rat
48. Intrinsic GABAergic neurons in the rat central extended amygdala
49. Paraventricular nucleus: A site for the integration of neuroendocrine and autonomic mechanisms
50. Hypothalamic integration: Organization of the paraventricular and supraoptic nuclei
51. Organization of projections from the dorsomedial nucleus of the hypothalamus: A PHA-L study in the rat
52. Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system