High payload dual therapeutic-imaging nanocarriers for triggered tumor delivery

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Volumn 8, Issue 18, 2012, Pages 2895-2903

  Kim, Jin Ki ^a,b   Yuan, Hong ^c   Nie, Jingxin ^c   Yang, Yu Tsai ^a   Leggas, Markos ^d   Potter, Philip M ^e   Rinehart, John ^f   Jay, Michael ^a,g   Lu, Xiuling ^h  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

^b Hanyang University   (South Korea)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d University of Kentucky   (United States)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^f UNIVERSITY OF KENTUCKY   (United States)

^g NORTH CAROLINA STATE UNIVERSITY   (United States)

^h UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

dexamethasone; ester prodrug; nanoparticles; SPECT CT imaging; triggered release

Indexed keywords

ANIMAL MODEL; BLOOD TEST; DEXAMETHASONES; DRUG DELIVERY SYSTEM; ESTERASE ACTIVITIES; HIGH-CONTENT; HUMAN PLASMAS; HUMAN TUMORS; IN-VITRO; INTERSTITIAL FLUID PRESSURES; LIVER ACCUMULATION; MOUSE PLASMA; NANOCARRIERS; PRODRUGS; SINGLE PHOTON EMISSION; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IMAGES; SPECT/CT; TRIGGERED RELEASE; TUMOR UPTAKE;

DRUG DELIVERY; ENZYMES; ESTERS; MAMMALS; NANOPARTICLES; PLASMA (HUMAN); PLASMAS; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY;

TUMORS;

ANIMALIA; MUS;

DEXAMETHASONE; DRUG CARRIER; INDIUM; NANOPARTICLE; PRODRUG; RADIOPHARMACEUTICAL AGENT;

ANIMAL; ARTICLE; CANCER TRANSPLANTATION; CHEMISTRY; FEMALE; HUMAN; METABOLISM; MOUSE; MOUSE MUTANT; NEOPLASM; NUDE MOUSE; SCINTISCANNING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; DEXAMETHASONE; DRUG CARRIERS; FEMALE; HUMANS; INDIUM RADIOISOTOPES; MICE; MICE, NUDE; MICE, SCID; NANOPARTICLES; NEOPLASM TRANSPLANTATION; NEOPLASMS; PRODRUGS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TRANSPLANTATION, HETEROLOGOUS;

EID: 84866367246     PISSN: 16136810     EISSN: 16136829     Source Type: Journal    
DOI: 10.1002/smll.201200437     Document Type: Article

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