No appetite efficacy of a commercial structured lipid emulsion in minimally processed drinks

International Journal of Obesity

Volumn 36, Issue 9, 2012, Pages 1222-1228

  Smit, H J ^a   Keenan, E ^a   Kovacs, E M R ^b   Wiseman, S A ^c   Mela, D J ^c   Rogers, P J ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

^c UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

appetite; emulsions; energy intake; fats; food manufacture; satiety response

Indexed keywords

LIPID EMULSION; PLACEBO; YOGHURT;

ADULT; APPETITE; ARTICLE; BODY MASS; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; FAT INTAKE; FEMALE; FOOD INTAKE; FOOD PROCESSING; HUMAN; HUMAN EXPERIMENT; MALE; MEAL; MOOD; NORMAL HUMAN; PARALLEL DESIGN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ANALYSIS OF VARIANCE; APPETITE; APPETITE DEPRESSANTS; CROSS-OVER STUDIES; DIETARY FATS; DOUBLE-BLIND METHOD; EMULSIONS; ENERGY INTAKE; FEEDING BEHAVIOR; FEMALE; GREAT BRITAIN; HUMANS; LIPIDS; MALE; MEALS; MIDDLE AGED; YOGURT; YOUNG ADULT;

EID: 84866366037     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2011.237     Document Type: Article

References (28)

1. Delgado-Aros S, Kim D-Y, Burton DD, Thomforde GM, Stephens D, Brinkmann BH et al. Effect of GLP-1 on gastric volume, emptying, maximum volume ingested, and postprandial symptoms in humans. Am J Physiol 2002; 282: G424-G431. (Pubitemid 34651657)
2. Brubaker PL, Drucker DJ, Asa SL, Swallow C, Redston M, Greenberg GR. Prolonged gastrointestinal transit in a patient with a glucagon-like peptide (GLP)-1-and-2-producing neuroendocrine tumor. J Clin Endocrinol Metab 2002; 87: 3078-3083. (Pubitemid 34816348)
3. Giralt M, Vergara P. Glucagonlike peptide-1 (GLP-1) participation in ileal brake induced by intraluminal peptones in rat. Dig Dis Sci 1999; 44: 322-329. (Pubitemid 29093556)
4. Näslund E, Bogefors J, Skogar S, Grybäck P, Jacobsson H, Holst JJ et al. GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans. Am J Physiol 1999; 277: R910-R916. (Pubitemid 29458166)
5. Maljaars PWJ, Peters HPF, Mela DJ, Masclee AAM. Ileal brake: a sensible food target for appetite control. A review. Physiol Behav 2008; 95: 271-281.
6. Knutson L, Koenders DJ, Fridblom H, Viberg A, Sein A, Lennernäs H. Gastrointestinal metabolism of a vegetable-oil emulsion in healthy subjects. Am J Clin Nutr 2010; 92: 515-524.
7. Fabuless-Map. http://www.dsm.com/le/en-US/fabuless/html/map.htm (accessed 2. September 2011).
8. Appleton KM, Smit HJ, Rogers PJ. Review and meta-analysis of the short-term effects of a vegetable oil emulsion on food intake. Obes Rev 2011; 12: e560-e572.
9. Burns AA, Livingstone MBE, Welch RW, Dunne A, Robson PJ, Lindmark L et al. Short-term effects of yoghurt containing a novel fat emulsion on energy and macronutrient intakes in non-obese subjects. Int J Obes 2000; 24: 1419-1425.
10. Burns AA, Livingstone MBE, Welch RW, Dunne A, Reid CA, Rowland IR. The effects of yoghurt containing a novel fat emulsion on energy and macronutrient intakes in non-overweight, overweight and obese subjects. Int J Obes 2001; 25: 1487-1496. (Pubitemid 32977867)
11. Burns AA, Livingstone MBE, Welch RW, Dunne A, Rowland IR. Dose-response effects of a novel fat emulsion (Olibrat) on energy and macronutrient intakes up to 36 h post-consumption. Eur J ClinNutr 2002; 56: 368-377. (Pubitemid 34414832)
12. Diepvens K, Steijns J, Zuurendonk P, Westerterp-Plantinga MS. Short-term effects of a novel fat emulsion on appetite and food intake. Physiol Behav 2008; 95: 114-117.
13. Smit HJ, Keenan E, Kovacs EMR, Wiseman SA, Peters HPF, Mela DJ et al. No efficacy of processed Fabuless (Olibra) in suppressing appetite or food intake. Eur J Clin Nutr 2011; 65: 81-86.
14. Chan Y-K, Strik CM, Budgett S, McGill A-T, Proctor J, Poppitt SD. The emulsified lipid Fabuless (Olibra) does not decrease food intake but suppresses appetite when consumed with yoghurt but not alone or with solid foods: a food effect study. Physiol Behav 2011; 105: 742-748.
15. Logan CM, McCaffrey TA, Wallace JMW, Robson PJ, Welch RW, Dunne A et al. Investigation of the medium-term effects of Olibrat fat emulsion on food intake in non-obese subjects. Eur J Clin Nutr 2006; 60: 1081-1091. (Pubitemid 44340407)
16. Van Strien T, Frijters JER, Bergers GPA, Defares PB. The Dutch eating behaviour questionnaire for assessment of restrained, emotional and external eating behaviour. Int J Eat Disord 1986; 5: 295-315. (Pubitemid 16141056)
17. Van Strien T, Frijters JER, Bergers GPA, Defares PB (eds). Nederlandse Vragenlijst voor Eetgedrag (NVE), handleiding, [Dutch Eating Behavior Questionnaire (DEBQ), manual]. Swets&Zeitlinger b.v.: Lisse, The Netherlands, 1986.
18. Davies J, Dickerson J. Nutrient Content of Food Portions. The Royal Society of Chemistry: Cambridge, UK, 1991.
19. Rogers PJ, Blundell JE. Effect of anorexic drugs on food intake and the microstructure of eating in human subjects. Psychopharmacology (Berl.) 1979; 66: 159-165. (Pubitemid 10180146)
20. Rolls BJ, Shide DJ, Thorwart ML, Ulbrecht JS. Sibutramine reduces food intake in non-dieting women with obesity. Obes Res 1998; 6: 1-11. (Pubitemid 128679638)
21. Blundell J, de Graaf C, Hulshof T, Jebb S, Livingstone B, Lluch A et al. Appetite control: methodological aspects of the evaluation of foods. Obes Rev 2010; 11: 251-270.
22. McClements DJ (ed.). Food Emulsions: Principles, Practice and Techniques, 2nd edn. CRC Press: Boca Raton, USA, 2005.
23. Lin HC, Zhao X-T, Wang L. Fat absorption is not complete by midgut but is dependent on load of fat. Am J Physiol 1996; 271: G62-G67. (Pubitemid 26299727)
24. Feinle C, O'Donovan D, Doran S, Andrews JM, Wishart J, Chapman I et al. Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans. Am J Physiol 2003; 284: G798-G807. (Pubitemid 36437980)
25. Näslund E, Grybäck P, Backman L, Jacobsson H, Holst JJ, Theodorsson E et al. Distal small bowel hormones: correlating with fasting antroduodenal motility and gastric emptying. Dig Dis Sci 1998; 43: 945-952. (Pubitemid 28211450)
26. Zhao X-T, Wang L, Lin HC. Slowing of intestinal transit by fat depends on naloxone-blockable efferent, opioid pathway. Am J Physiol 2000; 278: G866-G870. (Pubitemid 30439164)
27. Haenni A, Sundberg B, Yazdanpanah N, Viberg A, Olsson J. Effect of fat emulsion (Fabuless) on orocecal transit time in healthy men. Scand J Gastroenterol 2009; 44: 1186-1190.
28. Peters P, Beglinger C, Mela D, Schuring E. Comment and reply on: effect of emulsion (Fabuless) on orocecal transit time in healthy men. Scand J Gastroenterol 2010; 45: 637-638.