Varying fitness cost associated with resistance to fluoroquinolones governs clonal dynamic of methicillin-resistant Staphylococcus aureus

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 31, Issue 8, 2012, Pages 2029-2036

  Horvath A ^a   Dobay, O ^a   Kardos, S ^a   Ghidan A ^a   Toth A ^b   Paszti J ^b   Ungvari E ^b   Horvath P ^a   Nagy, K ^a   Zissman, S ^a   Fuzi M ^a  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^b NATIONAL CENTER FOR EPIDEMIOLOGY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; KANAMYCIN; METICILLIN; NUCLEOTIDE; OXACILLIN; PHENYLALANINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; SERINE; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIABILITY; BACTERIUM ISOLATION; CONTROLLED STUDY; COST; GERMANY; GRLA GENE; GRLB GENE; HUNGARY; JAPAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL COMMUNITY; MICROBIAL POPULATION DYNAMICS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; UNITED STATES;

ANTI-BACTERIAL AGENTS; COMMUNITY-ACQUIRED INFECTIONS; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; GENOTYPE; HUMANS; HUNGARY; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MOLECULAR EPIDEMIOLOGY; MUTATION;

EID: 84866364739     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-011-1536-z     Document Type: Article

References (30)

1. Deurenberg RH, Stobberingh EE (2008) The evolution of Staphylococcus aureus. Infect Genet Evol 8:747-763
2. Harris SR, Feil EJ, Holden MT, QuailMA, Nickerson EK, Chantratita N, Gardete S, Tavares A, Day N, Lindsay JA, Edgeworth JD, de Lencastre H, Parkhill J, Peacock SJ, Bentley SD (2010) Evolution of MRSA during hospital transmission and intercontinental spread. Science 327:469-474
3. Grundmann H, Aanensen DM, van den Wijngaard CC, Spratt BG, Harmsen D, Friedrich AW (2010) European Staphylococcal Reference Laboratory Working Group. Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a molecular-epidemiological analysis. PLoS Med 7:e1000215
4. Johnson AP (2011) Methicillin-resistant Staphylococcus aureus: the European landscape. J Antimicrob Chemother 66(Suppl 4): iV43-iV48
5. Conceição T, Aires-de-Sousa M, Füzi M, Tóth A, Pászti J, Ungvári E, van Leeuwen WB, van Belkum A, Grundmann H, de Lencastre H (2007) Replacement of methicillin-resistant Staphylococcus aureus clones in Hungary over time: a 10-year surveillance study. Clin Microbiol Infect 13:971-979 (Pubitemid 47382252)
6. Thouverez M, Muller A, Hocquet D, Talon D, Bertrand X (2003) Relationship between molecular epidemiology and antibiotic susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) in a French teaching hospital. J Med Microbiol 52:801-806 (Pubitemid 37174784)
7. Foucault ML, Courvalin P, Grillot-Courvalin C (2009) Fitness cost of Van A-type vancomycin resistance in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 53:2354-2359
8. Laurent F, Lelièvre H, Cornu M, Vandenesch F, Carret G, Etienne J, Flandrois JP (2001) Fitness and competitive growth advantage of new gentamicin-susceptible MRSA clones spreading in French hospitals. J Antimicrob Chemother 47:277-283 (Pubitemid 32229569)
9. Pantosti A, Sanchini A, Monaco M (2007) Mechanisms of antibiotic resistance in Staphylococcus aureus. Future Microbiol 2:323- 334 (Pubitemid 47180928)
10. Oliveira DC, de Lencastre H (2002) Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 46:2155-2161 (Pubitemid 34665910)
11. Clinical and Laboratory Standards Institute (2005) Performance Standards for Antimicrobial Susceptibility testing; 15th Informational supplement M100-S15. CLSI, Wayne, PA, USA
12. Schmitz FJ, Hofmann B, Hansen B, Scheuring S, Lückefahr M, Klootwijk M, Verhoef J, Fluit A, Heinz HP, Köhrer K, Jones ME (1998) Relationship between ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and moxifloxacin (BAY 12-8039) MICs and mutations in grlA, grlB, gyrA and gyrB in 116 unrelated clinical isolates of Staphylococcus aureus. J Antimicrob Chemother 41:481-484 (Pubitemid 28167507)
13. National Epidemiology Centre of Hungary (OEK) (2010) Antibiotic resistance. Based on the data reported in the frame of the national surveillance system. http://www.oek.hu/. Accessed 28 December 2011
14. Lee SM, Ender M, Adhikari R, Smith JM, Berger-Bächi B, Cook GM (2007) Fitness cost of staphylococcal cassette chromosome mec in methicillin-resistant Staphylococcus aureus by way of continuous culture. Antimicrob Agents Chemother 51:1497-1499 (Pubitemid 46586836)
15. Collins J, Rudkin J, Recker M, Pozzi C, O'Gara JP, Massey RC (2010) Offsetting virulence and antibiotic resistance costs by MRSA. ISME J 4:577-584
16. Hallin M, Denis O, Deplano A, De Ryck R, Crèvecoeur S, Rottiers S, de Mendonça R, Struelens MJ (2008) Evolutionary relationships between sporadic and epidemic strains of healthcare-associated methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect 14:659-669 (Pubitemid 351837026)
17. Ma XX, Ito T, Chongtrakool P, Hiramatsu K (2006) Predominance of clones carrying Panton-Valentine leukocidin genes among methicillin-resistant Staphylococcus aureus strains isolated in Japanese hospitals from 1979 to 1985. J Clin Microb 44:4515-4527 (Pubitemid 44937087)
18. Velazquez-Meza ME, Aires de Sousa M, Echaniz-Aviles G, Solórzano- Santos F, Miranda-Novales G, Silva-Sanchez J, de Lencastre H (2004) Surveillance of methicillin-resistant Staphylococcus aureus in a pediatric hospital in Mexico City during a 7-year period (1997 to 2003): clonal evolution and impact of infection control. J Clin Microbiol 42:6877-6880
19. Gagliotti C, Balode A, Baquero F, Degener J, Grundmann H, Gür D, Jarlier V, Kahlmeter G, Monen J, Monnet DL, Rossolini GM, Suetens C, Weist K, Heuer O (2011) Escherichia coli and Staphylococcus aureus: bad news and good news from the European Antimicrobial Resistance Surveillance Network (EARS-Net, formerly EARSS), 2002 to 2009. Eurosurveillance 16:pii:19819
20. Damjanova I, Tóth A, Pászti J, Bauernfeind A, Füzi M (2006) Nationwide spread of clonally related CTX-M-15-producing multidrug-resistant Klebsiella pneumoniae strains in Hungary. Eur J Clin Microbiol Infect Dis 25:275-278 (Pubitemid 43800551)
21. Damjanova I, Tóth A, Pászti J, Jakab M, Milch H, Bauernfeind A, Füzi M (2007) Epidemiology of SHV-type beta- lactamaseproducing Klebsiella spp. from outbreaks in five geographically distant Hungarian neonatal intensive care units: widespread dissemination of epidemic R-plasmids. Int J Antimicrob Agents 29:665-671 (Pubitemid 46710363)
22. Damjanova I, Tóth A, Pászti J, Hajbel-Vékony G, Jakab M, Berta J, Milch H, Füzi M (2008) Expansion and countrywide dissemination of ST11, ST15 and ST147 ciprofloxacin-resistant CTX-M-15-type beta-lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005-the new 'MRSAs'? J Antimicrob Chemother 62:978-985
23. Szilágyi E, FüziM, Damjanova I, Böröcz K, Szonyi K, Tóth A, Nagy K (2009) Investigation of extended-spectrum beta-lactamaseproducing Klebsiella pneumoniae outbreaks in Hungary between 2005 and 2008. Acta Microbiol Immunol Hung 57:43
24. Pan XS, Hamlyn PJ, Talens-Visconti R, Alovero FL, Manzo RH, Fisher LM (2002) Small-colony mutants of Staphylococcus aureus allow selection of gyrase-mediated resistance to dual-target fluoroquinolones. Antimicrob Agents Chemother 46:2498-2506 (Pubitemid 34793455)
25. Holden MT, Feil EJ, Lindsay JA, Peacock SJ, Day NP, Enright MC, Foster TJ, Moore CE, Hurst L, Atkin R, Barron A, Bason N, Bentley SD, Chillingworth C, Chillingworth T, Churcher C, Clark L, Corton C, Cronin A, Doggett J, Dowd L, Feltwell T, Hance Z, Harris B, Hauser H, Holroyd S, Jagels K, James KD, Lennard N, Line A, Mayes R, Moule S, Mungall K, Ormond D, Quail MA, Rabbinowitsch E, Rutherford K, Sanders M, Sharp S, Simmonds M, Stevens K, Whitehead S, Barrell BG, Spratt BG, Parkhill J (2004) Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci USA 101:9786-9791 (Pubitemid 38869314)
26. Herron-Olson L, Fitzgerald JR, Musser JM, Kapur V (2007) Molecular correlates of host specialization in Staphylococcus aureus. PLoS One 2:e1120
27. Schijffelen MJ, Boel CH, van Strijp JA, Fluit AC (2010) Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis. BMC Genomics 11:376
28. Guinane CM, Ben Zakour NL, Tormo-Mas MA, Weinert LA, Lowder BV, Cartwright RA, Smyth DS, Smyth CJ, Lindsay JA, Gould KA, Witney A, Hinds J, Bollback JP, Rambaut A, Penadés JR, Fitzgerald JR (2010) Evolutionary genomics of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation. Genome Biol Evol 2:454-466
29. Ikemura T (1981) Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system. J Mol Biol 151:389- 409 (Pubitemid 12252691)
30. Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, Gottesman MM (2007) A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 315:525- 528 (Pubitemid 46175758)