Interleukin-6 and cytochrome-P450, reason for concern?

Rheumatology International

Volumn 32, Issue 9, 2012, Pages 2601-2604

  Kim, Sooha ^a   Östör, Andrew J K ^b   Nisar, Muhammad K ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Biologics; Cytochrome P450; Drug interaction; Liver; Rheumatoid arthritis; Tocilizumab

Indexed keywords

ATORVASTATIN; BENZODIAZEPINE; CALCIUM CHANNEL BLOCKING AGENT; CYCLOSPORIN; CYTOCHROME P450; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; INTERLEUKIN 6; MESSENGER RNA; OMEPRAZOLE; SIMVASTATIN; THEOPHYLLINE; TOCILIZUMAB; WARFARIN;

AREA UNDER THE CURVE; CLINICAL TRIAL (TOPIC); DRUG BIOAVAILABILITY; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; RHEUMATOID ARTHRITIS;

ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL, HUMANIZED; ARTHRITIS, RHEUMATOID; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; HUMANS; INTERLEUKIN-6; RECEPTORS, INTERLEUKIN-6;

EID: 84866362076     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-012-2423-3     Document Type: Review

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