Phenylephrine-induced hypertension during transient middle cerebral artery occlusion alleviates ischemic brain injury in spontaneously hypertensive rats

Brain Research

Volumn 1477, Issue , 2012, Pages 83-91

  Kang, Byeong Teck ^a,b   Leoni, Renata F ^a,c   Kim, Dong Eog ^d   Silva, Afonso C ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b Chungbuk National University   (South Korea)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d Dongguk University Ilsan Hospital   (South Korea)

Author keywords

Arterial spin labeling; Cerebral blood flow; Hypertension; Ischemic stroke; Magnetic resonance imaging; Spontaneously hypertensive rat

Indexed keywords

PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APPARENT DIFFUSION COEFFICIENT; ARTICLE; BLOOD PRESSURE; BRAIN BLOOD FLOW; BRAIN CIRCULATION; BRAIN EDEMA; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN MAPPING; BRAIN PERFUSION; BRAIN SIZE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; HEMISPHERE; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC DISEASE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SPIN LABELING; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE;

ACUTE DISEASE; ANALYSIS OF VARIANCE; ANIMALS; BLOOD PRESSURE; BRAIN EDEMA; BRAIN INJURIES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; HYPERTENSION; INFARCTION, MIDDLE CEREBRAL ARTERY; MAGNETIC RESONANCE IMAGING; MALE; NEUROLOGIC EXAMINATION; PHENYLEPHRINE; RATS; RATS, INBRED SHR; REPERFUSION INJURY; STATISTICS, NONPARAMETRIC; TIME FACTORS; VASOCONSTRICTOR AGENTS;

RATTUS;

EID: 84866348112     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.08.024     Document Type: Article

References (33)

1. H.P. Adams Jr., G. del Zoppo, M.J. Alberts, D.L. Bhatt, L. Brass, A. Furlan, R.L. Grubb, R.T. Higashida, E.C. Jauch, C. Kidwell, P.D. Lyden, L.B. Morgenstern, A.I. Qureshi, R.H. Rosenwasser, P.A. Scott, and E.F. Wijdicks Guidelines for the early management of adults with ischemic stroke Stroke 38 2007 1655 1711
2. D.C. Alsop, and J.A. Detre Reduced transit-time sensitivity in noninvasive magnetic resonance imaging of human cerebral blood flow J. Cereb. Blood Flow Metab. 16 1996 1236 1249 (Pubitemid 26365376)
3. F. Amenta, M.A. Di Tullio, and D. Tomassoni Arterial hypertension and brain damage - evidence from animal models Clin. Exp. Hypertens 25 2003 359 380 (Pubitemid 36993241)
4. C. Ayata, and A.H. Ropper Ischaemic brain oedema J. Clin. Neurosci. 9 2002 113 124 (Pubitemid 34464579)
5. F.C. Barone, E.A. Irving, A.M. Ray, J.C. Lee, S. Kassis, S. Kumar, A.M. Badger, R.F. White, M.J. McVey, J.J. Legos, J.A. Erhardt, A.H. Nelson, E.H. Ohlstein, A.J. Hunter, K. Ward, B.R. Smith, J.L. Adams, and A.A. Parsons SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia J. Pharmacol. Exp. Ther. 296 2001 312 321 (Pubitemid 32112455)
6. J.A. Bevan, J. Duckworth, I. Laher, M.A. Oriowo, G.A. McPherson, and R.D. Bevan Sympathetic control of cerebral arteries: specialization in receptor type, reserve, affinity, and distribution FASEB J. 1 1987 193 198 (Pubitemid 18032623)
7. T. Brott, M. Lu, R. Kothari, S.C. Fagan, M. Frankel, J.C. Grotta, J. Broderick, T. Kwiatkowski, C. Lewandowski, E.C. Haley, J.R. Marler, and B.C. Tilley Hypertension and its treatment in the NINDS rt-PA stroke trial Stroke 29 1998 1504 1509 (Pubitemid 28365565)
8. J.A. Chalela, B. Dunn, J.W. Todd, and S. Warach Induced hypertension improves cerebral blood flow in acute ischemic stroke Neurology 64 2005 1979 (Pubitemid 40800724)
9. L. Chileuitt, K. Leber, T. McCalden, and P.R. Weinstein Induced hypertension during ischemia reduces infarct area after temporary middle cerebral artery occlusion in rats Surg. Neurol. 46 1996 229 234 (Pubitemid 26299059)
10. X. Chu, C. Qi, L. Zou, and X. Fu Intraluminal suture occlusion and ligation of the distal branch of internal carotid artery: an improved rat model of focal cerebral ischemia-reperfusion J. Neurosci. Methods 168 2008 1 7
11. D.J. Cole, J.C. Drummond, T.N. Osborne, and J. Matsumura Hypertension and hemodilution during cerebral ischemia reduce brain injury and edema Am. J. Physiol. 259 1990 H211 217
12. D.J. Cole, J.C. Drummond, T.S. Ruta, and N.H. Peckham Hemodilution and hypertension effects on cerebral hemorrhage in cerebral ischemia in rats Stroke 21 1990 1333 1339 (Pubitemid 20301791)
13. D.J. Cole, J.S. Matsumura, J.C. Drummond, and R.M. Schell Focal cerebral ischemia in rats: effects of induced hypertension, during reperfusion, on CBF J. Cereb. Blood Flow Metab. 12 1992 64 69
14. J.C. Drummond, Y.S. Oh, D.J. Cole, and H.M. Shapiro Phenylephrine-induced hypertension reduces ischemia following middle cerebral artery occlusion in rats Stroke 20 1989 1538 1544 (Pubitemid 19278142)
15. C.M. Geeganage, and P.M. Bath Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression Hypertension 54 2009 775 781
16. T. Gerriets, E. Stolz, M. Walberer, C. Müller, A. Kluge, A. Bachmann, M. Fisher, M. Kaps, and G. Bachmann Noninvasive quantification of brain edema and the space-occupying effect in rat stroke models using magnetic resonance imaging Stroke 35 2004 566 571 (Pubitemid 38174451)
17. H. Harms, F. Wiegand, D. Megow, K. Prass, K.M. Einhäupl, and U. Dirnagl Acute treatment of hypertension increases infarct sizes in spontaneously hypertensive rats Neuroreport 11 2000 355 359 (Pubitemid 30074649)
18. S. Ishikawa, H. Ito, K. Yokoyama, and K. Makita Phenylephrine ameliorates cerebral cytotoxic edema and reduces cerebral infarction volume in a rat model of complete unilateral carotid artery occlusion with severe hypotension Anesth. Analg. 108 2009 1631 1637
19. J. Leonardi-Bee, P.M. Bath, S.J. Phillips, and P.A. Sandercock Blood pressure and clinical outcomes in the international stroke trial Stroke 33 2002 1315 1320 (Pubitemid 34517053)
20. R.F. Leoni, F.F. Paiva, E.C. Henning, G.C. Nascimento, A. Tannús, D.B. de Araujo, and A.C. Silva Magnetic resonance imaging quantification of regional cerebral blood flow and cerebrovascular reactivity to carbon dioxide in normotensive and hypertensive rats Neuroimage 58 2011 75 81
21. E.Z. Longa, P.R. Weinstein, S. Carlson, and R. Cummins Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 91 (Pubitemid 19040218)
22. H. Lu, R. Leoni, A.C. Silva, E.A. Stein, and Y. Yang High-field continuous arterial spin labeling with long labeling duration: reduced confounds from blood transit time and postlabeling delay Magn. Reson. Med. 64 2010 1557 1566
23. C. McCabe, L. Gallagher, W. Gsell, D. Graham, A.F. Dominiczak, and I.M. Macrae Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats Stroke 40 2009 3864 3868
24. X. Meng, M. Fisher, Q. Shen, C.H. Sotak, and T.Q. Duong Characterizing the diffusion/perfusion mismatch in experimental focal cerebral ischemia Ann. Neurol. 55 2004 207 212 (Pubitemid 38166997)
25. G. Rordorf, W.J. Koroshetz, M.A. Ezzeddine, A.Z. Segal, and F.S. Buonanno A pilot study of drug-induced hypertension for treatment of acute stroke Neurology 56 2001 1210 1213 (Pubitemid 32405717)
26. D.A. Schwinn, R.W. McIntyre, and J.G. Reves Isoflurane-induced vasodilation: role of the alpha-adrenergic nervous system Anesth. Analg. 71 1990 451 459 (Pubitemid 20380591)
27. H.K. Shin, M. Nishimura, P.B. Jones, H. Ay, D.A. Boas, M.A. Moskowitz, and C. Ayata Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia Stroke 39 2008 1548 1555
28. A. Silva, W. Zhang, D. Williams, and A. Koretsky Multi-slice MRI of rat brain perfusion during amphetamine stimulation using arterial spin labeling Magn. Reson. Med. 33 1995 209 214
29. M. Smrcka, C.S. Ogilvy, R.J. Crow, K.I. Maynard, T. Kawamata, and A. Ames 3rd Induced hypertension improves regional blood flow and protects against infarction during focal ischemia: time course of changes in blood flow measured by laser Doppler imaging Neurosurgery 42 1998 617 625 (Pubitemid 28128746)
30. T.E. Sokrab, and B.B. Johansson Regional cerebral blood flow in acute hypertension induced by adrenaline, noradrenaline and phenylephrine in the conscious rat Acta Physiol. Scand. 137 1989 101 106
31. S. Strandgaard, J. Olesen, E. Skinhoj, and N.A. Lassen Autoregulation of brain circulation in severe arterial hypertension Brain Med. J. 1 1973 507 510
32. L. Symon, N.M. Branston, and A.J. Strong Autoregulation in acute focal ischemia. An experimental study Stroke 7 1976 547 554 (Pubitemid 8003009)
33. A.G. Waltz Effect of blood pressure on blood flow in ischemic and in nonischemic cerebral cortex. The phenomena of autoregulation and luxury perfusion Neurology 18 1968 613 621