Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia

Stroke

Volumn 39, Issue 5, 2008, Pages 1548-1555

  Shin, Hwa Kyoung ^a   Nishimura, Masaki ^a   Jones, Phillip B ^a   Ay, Hakan ^a   Boas, David A ^a   Moskowitz, Michael A ^a   Ayata, Cenk ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Stroke and Neurovascular Regulation Laboratory   (United States)

Author keywords

Cerebral metabolic rate of oxygen; Laser speckle flowmetry; Middle cerebral artery occlusion; Multispectral reflectance imaging; Stroke

Indexed keywords

OXYGEN; OXYHEMOGLOBIN; PHENYLEPHRINE; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BORDERLINE HYPERTENSION; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; FLOW MEASUREMENT; INDUCED HYPERTENSION; MEAN ARTERIAL PRESSURE; METABOLIC RATE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BRAIN CIRCULATION; CEREBRAL ARTERY DISEASE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; ENERGY METABOLISM; HOMEOSTASIS; HYPERTENSION; LASER DOPPLER FLOWMETRY; METABOLISM; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY; STROKE; TREATMENT OUTCOME;

ANIMALS; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; HOMEOSTASIS; HYPERTENSION; INFARCTION, MIDDLE CEREBRAL ARTERY; LASER-DOPPLER FLOWMETRY; MICE; OXYGEN CONSUMPTION; OXYHEMOGLOBINS; PHENYLEPHRINE; STROKE; TREATMENT OUTCOME; VASOCONSTRICTOR AGENTS;

EID: 44449083976     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.107.499483     Document Type: Article

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