-
1
-
-
0031969264
-
Angiogenesis and tumor metastasis
-
Zetter BR. Angiogenesis and tumor metastasis. Annu Rev Med 1998;49:407-424.
-
(1998)
Annu Rev Med
, vol.49
, pp. 407-424
-
-
Zetter, B.R.1
-
2
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0034092011
-
Tumor angiogenesis: Past, present and the near future
-
Kerbel RS. Tumor angiogenesis: Past, present and the near future. Carcinogenesis 2000;21:505-515.
-
(2000)
Carcinogenesis
, vol.21
, pp. 505-515
-
-
Kerbel, R.S.1
-
4
-
-
0142195911
-
Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors
-
Ruzinova MB, Schoer RA, Gerald W, et al. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell 2003;4:277-289.
-
(2003)
Cancer Cell
, vol.4
, pp. 277-289
-
-
Ruzinova, M.B.1
Schoer, R.A.2
Gerald, W.3
-
5
-
-
0034090097
-
Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation
-
Griffioen AW, Molema G. Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev 2000;52:237-268.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 237-268
-
-
Griffioen, A.W.1
Molema, G.2
-
6
-
-
0141621149
-
Canstatin inhibits Akt activation and induces Fas-dependent apoptosis in endothelial cells
-
Panka DJ, Mier JW. Canstatin inhibits Akt activation and induces Fas-dependent apoptosis in endothelial cells. J Biol Chem 2003;278:37632-37636.
-
(2003)
J Biol Chem
, vol.278
, pp. 37632-37636
-
-
Panka, D.J.1
Mier, J.W.2
-
7
-
-
34548821303
-
Thrombospondin-based antiangiogenic therapy
-
Zhang X, Lawler J. Thrombospondin-based antiangiogenic therapy. Microvasc Res 2007;74:90-99.
-
(2007)
Microvasc Res
, vol.74
, pp. 90-99
-
-
Zhang, X.1
Lawler, J.2
-
8
-
-
0034463222
-
Mechanistic insights on the inhibition of tumor angiogenesis
-
Jimenez B, Volpert OV. Mechanistic insights on the inhibition of tumor angiogenesis. J Mol Med 2001;78:663-672.
-
(2001)
J Mol Med
, vol.78
, pp. 663-672
-
-
Jimenez, B.1
Volpert, O.V.2
-
9
-
-
0037439693
-
2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway
-
LaVallee TM, Zhan XH, Johnson MS, et al. 2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway. Cancer Res 2003;63:468-475.
-
(2003)
Cancer Res
, vol.63
, pp. 468-475
-
-
LaVallee, T.M.1
Zhan, X.H.2
Johnson, M.S.3
-
10
-
-
0041785511
-
Wiring the angiogenic switch: Ras, Myc, and Thrombospondin-1
-
Volpert OV, Alani RM. Wiring the angiogenic switch: Ras, Myc, and Thrombospondin-1. Cancer Cell 2003;3:199-200.
-
(2003)
Cancer Cell
, vol.3
, pp. 199-200
-
-
Volpert, O.V.1
Alani, R.M.2
-
11
-
-
0025147371
-
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
-
Good DJ, Polverini PJ, Rastinejad F, et al. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci USA 1990;87:6624-6628.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6624-6628
-
-
Good, D.J.1
Polverini, P.J.2
Rastinejad, F.3
-
12
-
-
0028672529
-
The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin
-
Dameron KM, Volpert OV, Tainsky MA, et al. The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin. Cold Spring Harb Symp Quant Biol 1994;59:483-489.
-
(1994)
Cold Spring Harb Symp Quant Biol
, vol.59
, pp. 483-489
-
-
Dameron, K.M.1
Volpert, O.V.2
Tainsky, M.A.3
-
13
-
-
0033613226
-
Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats
-
Iruela-Arispe ML, Lombardo M, Krutzsch HC, et al. Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation 1999;100:1423-1431.
-
(1999)
Circulation
, vol.100
, pp. 1423-1431
-
-
Iruela-Arispe, M.L.1
Lombardo, M.2
Krutzsch, H.C.3
-
14
-
-
0035503689
-
Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-beta-dependent and-independent mechanisms
-
Miao WM, Seng WL, Duquette M, et al. Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-beta-dependent and-independent mechanisms. Cancer Res 2001;61:7830-7839.
-
(2001)
Cancer Res
, vol.61
, pp. 7830-7839
-
-
Miao, W.M.1
Seng, W.L.2
Duquette, M.3
-
15
-
-
0037051655
-
Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics
-
Reiher FK, Volpert OV, Jimenez B, et al. Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics. Int J Cancer 2002;98:682-689.
-
(2002)
Int J Cancer
, vol.98
, pp. 682-689
-
-
Reiher, F.K.1
Volpert, O.V.2
Jimenez, B.3
-
16
-
-
0030904193
-
Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells
-
Guo N, Krutzsch HC, Inman JK, et al. Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells. Cancer Res 1997;57:1735-1742.
-
(1997)
Cancer Res
, vol.57
, pp. 1735-1742
-
-
Guo, N.1
Krutzsch, H.C.2
Inman, J.K.3
-
17
-
-
20944443196
-
Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities
-
Haviv F, Bradley MF, Kalvin DM, et al. Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities. J Med Chem 2005;48:2838-2846.
-
(2005)
J Med Chem
, vol.48
, pp. 2838-2846
-
-
Haviv, F.1
Bradley, M.F.2
Kalvin, D.M.3
-
18
-
-
33747883001
-
A phase I study assessing the safety and pharmacokinetics of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with gemcitabine and cisplatin in patients with solid tumors
-
Gietema JA, Hoekstra R, de Fos FY, et al. A phase I study assessing the safety and pharmacokinetics of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with gemcitabine and cisplatin in patients with solid tumors. Ann Oncol 2006;17:1320-1327.
-
(2006)
Ann Oncol
, vol.17
, pp. 1320-1327
-
-
Gietema, J.A.1
Hoekstra, R.2
de Fos, F.Y.3
-
19
-
-
32444431721
-
Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: A safe combination
-
Hoekstra R, de Vos FY, Eskens FA, et al. Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: A safe combination. Eur J Cancer 2006;42:467-472.
-
(2006)
Eur J Cancer
, vol.42
, pp. 467-472
-
-
Hoekstra, R.1
de Vos, F.Y.2
Eskens, F.A.3
-
20
-
-
34548219477
-
ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis
-
Anderson JC, Grammer JR, Wang W, et al. ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis. Cancer Biol Ther 2007;6:454-462.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 454-462
-
-
Anderson, J.C.1
Grammer, J.R.2
Wang, W.3
-
21
-
-
33847701595
-
Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma
-
Yang Q, Tian Y, Liu S, et al. Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma. Cancer Res 2007;67:1716-1724.
-
(2007)
Cancer Res
, vol.67
, pp. 1716-1724
-
-
Yang, Q.1
Tian, Y.2
Liu, S.3
-
22
-
-
57149111052
-
Randomized, phase II study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced soft tissue sarcoma
-
Baker LH, Rowinsky EK, Mendelson D, et al. Randomized, phase II study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced soft tissue sarcoma. J Clin Oncol 2008;26:5583-5588.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5583-5588
-
-
Baker, L.H.1
Rowinsky, E.K.2
Mendelson, D.3
-
23
-
-
36749060830
-
Phase 2 study of ABT-510 in patients with previously untreated advanced renal cell carcinoma
-
Ebbinghaus S, Hussain M, Tannir N, et al. Phase 2 study of ABT-510 in patients with previously untreated advanced renal cell carcinoma. Clin Cancer Res 2007;13(22 Pt 1):6689-6695.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.22 PART 1
, pp. 6689-6695
-
-
Ebbinghaus, S.1
Hussain, M.2
Tannir, N.3
-
25
-
-
70449091904
-
The comparative oncology trials consortium: Using spontaneously occurring cancers in dogs to inform the cancer drug development pathway
-
Gordon I, Paoloni M, Mazcko C, et al. The comparative oncology trials consortium: Using spontaneously occurring cancers in dogs to inform the cancer drug development pathway. PLoS Med 2009;6:e1000161.
-
(2009)
PLoS Med
, vol.6
-
-
Gordon, I.1
Paoloni, M.2
Mazcko, C.3
-
26
-
-
0020396015
-
Toxicity and response criteria of the eastern cooperative oncology group
-
Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the eastern cooperative oncology group. Am J Clin Oncol 1982;5:649-655.
-
(1982)
Am J Clin Oncol
, vol.5
, pp. 649-655
-
-
Oken, M.M.1
Creech, R.H.2
Tormey, D.C.3
-
27
-
-
33846221453
-
Cooperative activity of cytotoxic chemotherapy with antiangiogenic thrombospondin-I peptides, ABT-526 in pet dogs with relapsed lymphoma
-
Rusk A, Cozzi E, Stebbins M, et al. Cooperative activity of cytotoxic chemotherapy with antiangiogenic thrombospondin-I peptides, ABT-526 in pet dogs with relapsed lymphoma. Clin Cancer Res 2006;12:7456-7464.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7456-7464
-
-
Rusk, A.1
Cozzi, E.2
Stebbins, M.3
-
28
-
-
33846228382
-
Preclinical evaluation of antiangiogenic thrombospondin-1 peptide mimetics, ABT-526 and ABT-510, in companion dogs with naturally occurring cancers
-
Rusk A, McKeegan E, Haviv F, et al. Preclinical evaluation of antiangiogenic thrombospondin-1 peptide mimetics, ABT-526 and ABT-510, in companion dogs with naturally occurring cancers. Clin Cancer Res 2006;12:7444-7455.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7444-7455
-
-
Rusk, A.1
McKeegan, E.2
Haviv, F.3
-
29
-
-
38549112058
-
Translation of new cancer treatments from pet dogs to humans
-
Paoloni M, Khanna C. Translation of new cancer treatments from pet dogs to humans. Nat Rev Cancer 2008;8:147-156.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 147-156
-
-
Paoloni, M.1
Khanna, C.2
-
30
-
-
0038367708
-
Circulating endothelial cells as a novel marker of angiogenesis
-
Mancuso P, Calleri A, Cassi C, et al. Circulating endothelial cells as a novel marker of angiogenesis. Adv Exp Med Biol 2003;522:83-97.
-
(2003)
Adv Exp Med Biol
, vol.522
, pp. 83-97
-
-
Mancuso, P.1
Calleri, A.2
Cassi, C.3
-
31
-
-
33750286135
-
The multifaceted circulating endothelial cell in cancer: Towards marker and target identification
-
Bertolini F, Shaked Y, Mancuso P, et al. The multifaceted circulating endothelial cell in cancer: Towards marker and target identification. Nat Rev Cancer 2006;6:835-845.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 835-845
-
-
Bertolini, F.1
Shaked, Y.2
Mancuso, P.3
-
32
-
-
33745939679
-
Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy
-
Mancuso P, Colleoni M, Calleri A, et al. Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy. Blood 2006;108:452-459.
-
(2006)
Blood
, vol.108
, pp. 452-459
-
-
Mancuso, P.1
Colleoni, M.2
Calleri, A.3
-
33
-
-
35148820611
-
Molecular and cellular biomarkers for angiogenesis in clinical oncology
-
Bertolini F, Mancuso P, Shaked Y, et al. Molecular and cellular biomarkers for angiogenesis in clinical oncology. Drug Discov Today 2007;12:806-812.
-
(2007)
Drug Discov Today
, vol.12
, pp. 806-812
-
-
Bertolini, F.1
Mancuso, P.2
Shaked, Y.3
-
34
-
-
0035383784
-
Resting and activated endothelial cells are increased in the peripheral blood of cancer patients
-
Mancuso P, Burlini A, Pruneri G, et al. Resting and activated endothelial cells are increased in the peripheral blood of cancer patients. Blood 2001;97:3658-3661.
-
(2001)
Blood
, vol.97
, pp. 3658-3661
-
-
Mancuso, P.1
Burlini, A.2
Pruneri, G.3
-
35
-
-
27144468094
-
Cellular and molecular surrogate markers to monitor targeted and non-targeted antiangiogenic drug activity and determine optimal biologic dose
-
Shaked Y, Bocci G, Munoz R, et al. Cellular and molecular surrogate markers to monitor targeted and non-targeted antiangiogenic drug activity and determine optimal biologic dose. Curr Cancer Drug Targets 2005;5:551-559.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 551-559
-
-
Shaked, Y.1
Bocci, G.2
Munoz, R.3
-
36
-
-
70350464165
-
Phase I and biomarker study of ABT-869, a multiple receptor tyrosine kinase inhibitor, in patients with refractory solid malignancies
-
Wong CI, Koh TS, Soo R, et al. Phase I and biomarker study of ABT-869, a multiple receptor tyrosine kinase inhibitor, in patients with refractory solid malignancies. J Clin Oncol 2009;27:4718-4726.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4718-4726
-
-
Wong, C.I.1
Koh, T.S.2
Soo, R.3
-
37
-
-
34250847596
-
Circulating endothelial cells and endothelial progenitors as surrogate biomarkers in vascular dysfunction
-
Wu H, Chen H, Hu PC. Circulating endothelial cells and endothelial progenitors as surrogate biomarkers in vascular dysfunction. Clin Lab 2007;53:285-295.
-
(2007)
Clin Lab
, vol.53
, pp. 285-295
-
-
Wu, H.1
Chen, H.2
Hu, P.C.3
-
38
-
-
0033027727
-
Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat
-
Dawson DW, Volpert OV, Pearce SF, et al. Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat. Mol Pharmacol 1999;55:332-338.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 332-338
-
-
Dawson, D.W.1
Volpert, O.V.2
Pearce, S.F.3
-
40
-
-
0024536437
-
Optimal two-stage designs for pre-clinical trials
-
Simon R. Optimal two-stage designs for pre-clinical trials. Control Clin Trials 1989;10:1-10.
-
(1989)
Control Clin Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
41
-
-
26844522727
-
Veterinary co-operative oncology group-common terminology criteria for adverse events (VCOG-CTCAE) following chemotherapy or biological antineoplastic therapy in dogs and cats v1.0
-
VCOG) V. C.-o. O. G.
-
(VCOG) V. C.-o. O. G. Veterinary co-operative oncology group-common terminology criteria for adverse events (VCOG-CTCAE) following chemotherapy or biological antineoplastic therapy in dogs and cats v1.0. Vet Comp Oncol 2004;2:195-213.
-
(2004)
Vet Comp Oncol
, vol.2
, pp. 195-213
-
-
|