G894T polymorphism of eNOS gene is a predictor of response to combination of inhaled corticosteroids with long-lasting 2-agonists in asthmatic children

Pharmacogenomics

Volumn 13, Issue 12, 2012, Pages 1363-1372

  Iordanidou, Maria ^a,b   Paraskakis, Emmanouil ^b   Tavridou, Anna ^a,b   Paschou, Peristera ^a   Chatzimichael, Athanasios ^b   Manolopoulos, Vangelis G ^a,b  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b Academic General Hospital Alexandroupolis   (Greece)

Author keywords

786T C polymorphism; asthma; children; drug response; eNOS gene; G894T polymorphism; inhaled corticosteroids; long lasting 2 agonists; NOS3 gene; pharmacogenetic marker

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE PLUS FORMOTEROL; CORTICOSTEROID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUTICASONE PROPIONATE PLUS SALMETEROL;

ADOLESCENT; ARTICLE; ASTHMA; CHILD; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG RESPONSE; ENOS GENE; FEMALE; FORCED EXPIRATORY VOLUME; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; SCHOOL CHILD;

ADMINISTRATION, INHALATION; ADOLESCENT; ADRENAL CORTEX HORMONES; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ANTI-ASTHMATIC AGENTS; ASTHMA; CHILD; CHILD, PRESCHOOL; DRUG THERAPY, COMBINATION; FEMALE; GENOTYPE; HUMANS; NITRIC OXIDE SYNTHASE TYPE III; POLYMORPHISM, GENETIC;

EID: 84866321027     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.12.120     Document Type: Article

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