Embryonic Demise Caused by Targeted Disruption of a Cysteine Protease Dub-2

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Baek, Kwang Hyun ^a   Lee, Heyjin ^a   Yang, Sunmee ^a   Lim, Soo Bin ^a   Lee, Wonwoo ^a   Lee, Jeoung Eun ^a   Lim, Jung Jin ^a   Jun, Kisun ^a   Lee, Dong Ryul ^a   Chung, Young ^a  

^a CHA University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; PROTEIN DUB 2; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SIZE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DUB 2 GENE; EMBRYO; EMBRYO CELL; EMBRYO DEATH; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENZYME ACTIVITY; EXON; FEMALE; FERTILITY; GENE; GENE CASSETTE; GENE DISRUPTION; GENE FUNCTION; GENE TARGETING; HETEROZYGOTE; HOMOLOGOUS RECOMBINATION; MALE; MOUSE; NEWBORN; NEWBORN MORTALITY; NONHUMAN; PHENOTYPE;

ANIMALS; APOPTOSIS; BLASTOCYST INNER CELL MASS; CELL PROLIFERATION; CELL SURVIVAL; EMBRYO LOSS; EMBRYONIC DEVELOPMENT; ENDOPEPTIDASES; FERTILIZATION IN VITRO; GENE DELETION; GENE TARGETING; GENOTYPING TECHNIQUES; HETEROZYGOTE; IMMEDIATE-EARLY PROTEINS; LYMPHOID TISSUE; MALE; MICE; MICE, MUTANT STRAINS; PHENOTYPE; SPERM MOTILITY; SPERMATOZOA; SPLEEN; THYMUS GLAND;

MUS;

EID: 84866314325     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044223     Document Type: Article

References (41)

1. Amerik AY, Hochstrasser M, (2004) Mechanism and function of deubiquitinating enzymes. Biochim Biophys Acta 1695: 189-207.
2. Baek KH, (2006) Cytokine-regulated protein degradation by the ubiquitination system. Curr Protein Pept Sci 7: 171-177.
3. Glickman MH, Ciechanover A, (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428.
4. Ciechanover A, Orian A, Schwartz AL (2000) The ubiquitin-mediated proteolytic pathway: mode of action and clinical implications. J Cell Biochem Suppl 34: 40-51.
5. Sorokin AV, Kim ER, Ovchinnikov LP, (2009) Proteasome system of protein degradation and processing. Biochemistry (Mosc) 74: 1411-1442.
6. Ciechanover A, (1998) Ubiquitin-proteasome pathway: on protein death and cell life. EMBO J 17: 7151-7160.
7. Koegl M, Hoppe T, Schlenker S, Ulrich HD, Mayer TU, et al. (1999) A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell 96: 635-644.
8. D'Andrea A, Pellman D, (1998) Deubiquitinating enzymes: a new class of biological regulators. Crit Rev Biochem Mol Biol 33: 337-352.
9. Reyes-Turcu FE, Ventii KH, Wilkinson KD, (2009) Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem 78: 363-397.
10. Ambroggio XI, Rees DC, Deshaies RJ, (2004) JAMM: a metalloprotease-like zinc site in the proteasome and signalosome. PLoS Biol 2: e2.
11. Balakirev MY, Tcherniuk SO, Jaquinod M, Chroboczek J, (2003) Otubains: a new family of cysteine proteases in the ubiquitin pathway. EMBO Rep 4: 517-522.
12. Mao Y, Senic-Matuglia F, Di Fiore PP, Polo S, Hodsdon ME, et al. (2005) Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain. Proc Natl Acad Sci USA 102: 12700-12705.
13. Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, et al. (2005) A genomic and functional inventory of deubiquitinating enzymes. Cell 123: 773-786.
14. Ande SR, Chen J, Maddika S, (2009) The ubiquitin pathway: an emerging drug target in cancer therapy. Eur J Pharmacol 625: 199-205.
15. Hoeller D, Dikic I, (2009) Targeting the ubiquitin system in cancer therapy. Nature 458: 438-444.
16. Hussain S, Zhang Y, Galardy PJ, (2009) DUBs and cancer: the role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors. Cell Cycle 8: 1688-1697.
17. Baek KH, Kim MS, Kim YS, Shin JM, Choi HK, (2004) DUB-1A, a novel subfamily member of deubiquitinating enzyme, is polyubiquitinated and cytokine inducible in B-lymphocytes. J Biol Chem 279: 2368-2376.
18. Migone TS, Humbert M, Rascle A, Sanden D, D'Andrea A, et al. (2001) The deubiquitinating enzyme DUB-2 prolongs cytokine-induced signal transducers and activators of transcription activation and suppresses apoptosis following cytokine withdrawal. Blood 98: 1935-1941.
19. Zhu Y, Carroll M, Papa FR, Hochstrasser M, D'Andrea AD, (1996) DUB-1, a deubiquitinating enzyme with growth-suppressing activity. Proc Natl Acad Sci USA 93: 3275-3279.
20. Zhu Y, Pless M, Inhorn R, Mathey-Prevot B, D'Andrea AD, (1996) The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor. Mol Cell Biol 16: 4808-4817.
21. Zhu Y, Lambert K, Corless C, Copeland NG, Gilbert DJ, et al. (1997) DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. J Biol Chem 272: 51-57.
22. Burrows JF, McGrattan MJ, Rascle A, Humbert M, Baek KH, et al. (2004) DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation. J Biol Chem 279: 13993-14000.
23. Burrows JF, Kelvin AA, McFarlane C, Burden RE, McGrattan MJ, et al. (2009) USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity. J Biol Chem 284: 9587-9595.
24. Ramakrishna S, Suresh B, Lee EJ, Lee HJ, Ahn WS, et al. (2011) Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J Biol Chem 286: 10505-10514.
25. Ramakrishna S, Suresh B, Bae S-M, Ahn W-S, Lim K-H, et al. (2012) Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity. PLoS ONE 7: e37772.
26. Schwartz AL, Ciechanover A, (1999) The ubiquitin-proteasome pathway and pathogenesis of human diseases. Annu Rev Med 50: 57-74.
27. Ardley HC, Robinson PA, (2004) The role of ubiquitin-protein ligases in neurodegenerative disease. Neurodegener Dis 1: 71-87.
28. Layfield R, Alban A, Mayer RJ, Lowe J, (2001) The ubiquitin protein catabolic disorders. Neuropathol Appl Neurobiol 27: 171-179.
29. Kawamura K, Sato N, Fukuda J, Kodama H, Kumagai J, et al. (2003) Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos. Dev Biol 256: 331-341.
30. Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, et al. (2003) Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 17: 126-140.
31. Ayton P, Sneddon SF, Palmer DB, Rosewell IR, Owen MJ, et al. (2001) Truncation of the Mll gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos. Genesis 30: 201-212.
32. de La Coste A, Freitas AA, (2006) Notch signaling: distinct ligands induce specific signals during lymphocyte development and maturation. Immunol Lett 102: 1-9.
33. Sharma N, Liu S, Tang L, Irwin J, Meng G, et al. (2006) Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation. BMC Dev Biol 6: 61.
34. Kawaguchi M, Yasumasu S, Hiroi J, Naruse K, Suzuki T, et al. (2007) Analysis of the exon-intron structures of fish, amphibian, bird and mammalian hatching enzyme genes, with special reference to the intron loss evolution of hatching enzyme genes in Teleostei. Gene 392: 77-88.
35. Mbikay M, Croissandeau G, Sirois F, Anini Y, Mayne J, et al. (2007) A targeted deletion/insertion in the mouse Pcsk1 locus is associated with homozygous embryo preimplantation lethality, mutant allele preferential transmission and heterozygous female susceptibility to dietary fat. Dev Biol 306: 584-598.
36. Levy R, (2001) Genetic regulation of preimplantation embryo survival. Int Rev Cytol 210: 1-37.
37. Lindsay LL, Wallace MA, Hedrick JL, (2001) A hatching enzyme substrate in the Xenopus laevis egg envelope is a high molecular weight ZPA homolog. Dev Growth Differ 43: 305-313.
38. Handyside AH, Hunter S, (1984) A rapid procedure for visualising the inner cell mass and trophectoderm nuclei of mouse blastocysts in situ using polynucleotide-specific fluorochromes. J Exp Zool 231: 429-434.
39. Tripathi R, Mishra DP, Shaha C, (2009) Male germ cell development: turning on the apoptotic pathways. J Reprod Immunol 83: 31-35.
40. Kon N, Kobayashi Y, Li M, Brooks CL, Ludwig T, et al. (2010) Inactivation of HAUSP in vivo modulates p53 function. Oncogene 29: 1270-1279.
41. Wright A, Reiley WW, Chang M, Jin W, Lee AJ, et al. (2007) Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev Cell 13: 705-716.