Ghibe river basin in Ethiopia: Present situation of trypanocidal drug resistance in Trypanosoma congolense using tests in mice and PCR-RFLP

Veterinary Parasitology

Volumn 189, Issue 2-4, 2012, Pages 197-203

  Moti, Y ^a   Fikru, R ^b   Van Den Abbeele, J ^c   Buscher P ^c   Van den Bossche, P ^c,d   Duchateau, L ^e   Delespaux, V ^c  

^a JIMMA UNIVERSITY   (Ethiopia)

^b ADDIS ABABA UNIVERSITY   (Ethiopia)

^c INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^d UNIVERSITY OF PRETORIA   (South Africa)

^e GHENT UNIVERSITY   (Belgium)

Author keywords

Diminazene; Drug resistance; Ethiopia; Ghibe; Isometamidium; Trypanosoma congolense

Indexed keywords

DIMINAZENE ACETURATE; ISOMETAMIDIUM;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CATTLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DRUG SENSITIVITY; ETHIOPIA; FEMALE; IN VIVO STUDY; MALE; NAGANA; NONHUMAN; PARASITE CONTROL; PARASITE IDENTIFICATION; PARASITE ISOLATION; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TRYPANOSOMA CONGOLENSE;

ANIMALS; CATTLE; ETHIOPIA; FEMALE; MALE; MICE; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PREVALENCE; RISK FACTORS; RIVERS; RNA, PROTOZOAN; RNA, RIBOSOMAL, 18S; TRYPANOCIDAL AGENTS; TRYPANOSOMA CONGOLENSE; TRYPANOSOMIASIS, AFRICAN;

ANIMALIA; BOS; MUS; TRYPANOSOMA CONGOLENSE;

EID: 84866303001     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2012.04.022     Document Type: Article

References (31)

1. Avila H., Goncalves A.M., Nehme N.S., Morel C.M., Simpson L. Schizodeme analysis of Trypanosoma cruzi stocks from South and Central America by analysis of Pcr-amplified minicircle variable region sequences. Mol. Biochem. Parasitol. 1990, 42:175-187.
2. Chaka H., Abebe G. Drug resistant trypanosomes: a threat to cattle production in the Southwest of Ethiopia. Rev. Elev. Méd. Vét. Pays Trop. 2003, 56:33-36.
3. Codjia V., Mulatu W., Majiwa P.A.O., Leak S.G.A., Rowlands G.J., Authie E., Dieteren G.D.M., Peregrine A.S. Epidemiology of bovine trypanosomiasis in the Ghibe Valley Southwest Ethiopia. Occurrence of populations of Trypanosoma congolense resistant to diminazene, isometamidium and homidium. Acta Trop. 1993, 53:151-163.
4. de Almeida P.J.L.P., Ndao M., Goossens B., Osaer S. PCR primer evaluation for the detection of trypanosome DNA in naturally infected goats. Vet. Parasitol. 1998, 80:111-116.
5. Delespaux V., Chitanga S., Geysen D., Goethals A., Van den Bossche P., Geerts S. SSCP analysis of the P2 purine transporter TcoAT1 gene of Trypanosoma congolense leads to a simple PCR-RFLP test allowing the rapid identification of diminazene resistant stocks. Acta Trop. 2006, 100:96-102.
6. Delespaux V., Geysen D., Van den Bossche P., Geerts S. Molecular tools for the rapid detection of drug resistance in animal trypanosomes. Trends Parasitol. 2008, 24:236-242.
7. Delespaux V., Vitouley H.S., Marcotty T., Speybroeck N., Berkvens D., Roy K., Geerts S., Van den Bossche P. Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracycline and fluoroquinolone. PLoS Negl. Trop. Dis. 2010, 4:e828. 10.1371/journal.pntd.0000828.
8. Eisler M.C., Brandt J., Bauer B., Clausen P.H., Delespaux V., Holmes P.H., Ilemobade A., Machila N., Mbwambo H., McDermott J.J., Mehlitz D., Murilla G.A., Ndung'u J.M., Peregrine A.S., Sidibe I., Sinyangwe L., Geerts S. Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle. Vet. Parasitol. 2001, 97:171-182.
9. Eisler M.C., McDermott J.J., Mdachi R.E., Murilla G.A., Sinyangwe L., Mubanga J., Machila N., Mbwambo H., Coleman P., Clausen P.H., Bauer B., Sidibe I., Geerts S., Holmes P.H., Peregrine A.S. Rapid method for the assessment of trypanocidal drug resistance in the field. Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics 2000, 1-3. (paper 353). http://www.sciquest.org.nz/node/71200.
10. FAO Program Against African Trypanosomiasis (PAAT) - Twenty-second Regional Conference for Africa 2002.
11. Geerts S., Holmes P.H., Diall O., Eisler M.C. African bovine trypanosomiasis: the problem of drug resistance. Trends Parasitol. 2001, 17:25-28.
12. Getachew A. Trypanosomosis in Ethiopia. Ethiop. J. Biol. Sci. 2005, 4:75-121.
13. Geysen D., Delespaux V., Geerts S. PCR-RFLP using Ssu-rDNA amplification as an easy method for species-specific diagnosis of Trypanosoma species in cattle. Vet. Parasitol. 2003, 110:171-180.
14. Girma, B., 2010. Environmental impact monitoring for Gilgel Gibe I dam using an integrated method of remote sensing and geographic information system. Master of Science Thesis, Addis Abbaba University, School of Graduate Studies, Department of Earth Sciences, pp. 1-81.
15. Herbert W.J., Lumsden W.H.R. Trypanosoma brucei: a rapid "matching" method for estimating the host's parasitaemia. Exp. Parasitol. 1976, 40:427-431.
16. Holmes P.H. New approaches to the integrated control of trypanosomosis. Vet. Parasitol. 1997, 71:121-135.
17. Leak S.G.A., Mulatu W., Authie E., Dieteren G.D.M., Peregrine A.S., Rowlands G.J., Trail J.C.M. Epidemiology of bovine trypanosomiasis in the Ghibe Valley Southwest Ethiopia. 1. Tsetse challenge and its relationship to trypanosome prevalence in cattle. Acta Trop. 1993, 53:121-134.
18. Lemecha H., Mulatu W., Hussein I., Rege E., Tekle T., Abdicho S., Ayalew W. Response of four indigenous cattle breeds to natural tsetse and trypanosomosis challenge in the Ghibe valley of Ethiopia. Vet. Parasitol. 2006, 141:165-176.
19. Matovu E., Mäser P. Drug resistance in African trypanosomiasis. Antimicrobial Resistance in Developping Countries 2010, 157-176. Springer. A. Sosa, D. Byarugaba, D.K. Amabile-Cuevas, C.F. Hsueh, P.R. Kariuki, S.I.N. Okeke (Eds.).
20. Mulugeta W., Wilkes J.M., Mulatu W., Majiwa P.A.O., Masake R., Peregrine A.S. Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia. Acta Trop. 1997, 64:205-217.
21. Peregrine A.S., Gray M.A., Moloo S.K. Cross-resistance associated with development of resistance to isometamidium in a clone of Trypanosoma congolense. Antimicrob. Agents Chemother. 1997, 41:1604-1606.
22. Rowlands G.J., Authie E., d'Ieteren G., Mulatu W., Peregrine A.S., Leak S.G.A. An epidemiological study of recurrent trypanosome infection in East African zebu cattle and its association with drug resistance. Proceedings of the 6th International Society of Veterinary Epidemiology and Economics 1991, 444-446.
23. Rowlands G.J., Leak S.G.A., Peregrine A.S., Nagda S.M., Mulatu W., d'Ieteren G.D.M. The incidence of new and the prevalence and persistence of recurrent trypanosome infections in cattle in southwest Ethiopia exposed to a high challenge with drug-resistant parasites. Acta Trop. 2001, 79:149-163.
24. Rowlands G.J., Mulatu W., Authie E., Dieteren G.D.M., Leak S.G.A., Nagda S.M., Peregrine A.S. Epidemiology of bovine trypanosomiasis in the Ghibe Valley Southwest Ethiopia. Factors associated with variations in trypanosome prevalence, incidence of new infections and prevalence of recurrent infections. Acta Trop. 1993, 53:135-150.
25. Tewelde N., Abebe G., Eisler M.C., McDermott J.J., Greiner M., Afework Y., Kyule M., Munstermann S., Zessin K.H., Clausen P.H. Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia. Acta Trop. 2004, 90:163-170.
26. Thrusfield M. Data collection and management. Veterinary Epidemiology 1995, Black Well Science, Oxford, U.K., pp. 188-265.
27. Van den Bossche P., Chitanga S., Masumu J., Marcotty T., Delespaux V. Virulence in Trypanosoma congolense Savannah subgroup. A comparison between strains and transmission cycles. Parasite Immunol. 2011, 33:456-460. 10.1111/j.1365-3024.2010.01277.x.
28. Van den Bossche P., Delespaux V. Options for the control of tsetse-transmitted livestock trypanosomosis. An epidemiological perspective. Vet. Parasitol. 2011, 181:37-42. 8 - EVPC (European Veterinary Parasitology College) Special Issue.
29. Vitouley H.S., Mungube E.O., Allegye-Cudjoe E., Diall O., Bocoum Z., Diarra B., Randolph T., Bauer B., Clausen P.H., Geysen D., Sidibe I., Bengaly Z., Van den Bossche P., Delespaux V. Improved PCR-RFLP for the detection of diminazene resistance in Trypanosoma congolense under field conditions using filter papers for sample storage. PLoS Negl. Trop. Dis. 2011, 5:7-e1223. 10.1371/journal.pntd.0001223.
30. Whiteside E.F. The control of cattle trypanosomiasis with drugs in Kenya: methods and costs. East Afr. Agr. J. 1962, 28:67-73.
31. Woo P.T.K. The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis. Acta Trop. 1970, 27:384-387.