Involvement of lipid rafts in multiple signal transductions mediated by two isoforms of thromboxane A2 receptor: Dependency on receptor isoforms and downstream signaling types

European Journal of Pharmacology

Volumn 693, Issue 1-3, 2012, Pages 15-24

  Goto, Shinji ^a   Saito, Masaki ^a   Obara, Yutaro ^a   Moriya, Takahiro ^a   Nakahata, Norimichi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

cAMP; Lipid raft; Phosphatidylinositol hydrolysis; RhoA; Thromboxane A2 receptor

Indexed keywords

BETA ADRENERGIC RECEPTOR; CYCLIC AMP; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; METHYL BETA CYCLODEXTRIN; PHOSPHATIDYLINOSITOL; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBOXANE A2 RECEPTOR; THROMBOXANE A2 RECEPTOR ALPHA; THROMBOXANE A2 RECEPTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOACCUMULATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROLYSIS; LIPID RAFT; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SUCROSE DENSITY GRADIENT CENTRIFUGATION; WESTERN BLOTTING;

BETA-CYCLODEXTRINS; CYCLIC AMP; HEK293 CELLS; HUMANS; L-LACTATE DEHYDROGENASE; MEMBRANE MICRODOMAINS; PROTEIN ISOFORMS; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84866283403     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.07.046     Document Type: Article

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