Evaluation of mobile phase gradient supercritical fluid chromatography for impurity profiling of pharmaceutical compounds

Journal of Pharmaceutical and Biomedical Analysis

Volumn 70, Issue , 2012, Pages 77-86

  Alexander, A J ^a   Hooker, T F ^a   Tomasella, F P ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Active pharmaceutical ingredient; Impurity profiling; Pharmaceutical; SFC baseline noise; Supercritical fluid chromatography

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENT; DRUG; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DENSITY GRADIENT; DRUG IMPURITY; DRUG SCREENING; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; SUPERCRITICAL FLUID CHROMATOGRAPHY; TEMPERATURE;

ARTIFACTS; BUFFERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; CHROMATOGRAPHY, SUPERCRITICAL FLUID; DRUG CONTAMINATION; HYDROGEN-ION CONCENTRATION; LIMIT OF DETECTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TEMPERATURE;

EID: 84866262262     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.05.025     Document Type: Article

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