Integration of supercritical fluid chromatography into drug discovery as a routine support tool: Part I. Fast chiral screening and purification

Journal of Chromatography A

Volumn 1074, Issue 1-2, 2005, Pages 163-173

  White, Craig ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Chiral; Drug discovery; Enantiomer separation; Gradient screening; Supercritical fluid chromatography

Indexed keywords

DRUG PRODUCTS; PURIFICATION; SCREENING; SEPARATION; SOLVENTS; STEREOCHEMISTRY; SUPERCRITICAL FLUIDS;

CHIRAL SCREENING; DIASTEREOMERS; DRUG DISCOVERY; SUPERCRITICAL FLUID CHROMATOGRAPHY (SFC);

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

2 PROPANOL; ALCOHOL; METHANOL; SOLVENT;

ANALYTICAL EQUIPMENT; ARTICLE; CHIRALITY; DIASTEREOISOMER; DRUG IDENTIFICATION; DRUG PURIFICATION; DRUG SCREENING; FEASIBILITY STUDY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SUPERCRITICAL FLUID CHROMATOGRAPHY;

EID: 18144376699     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2005.03.073     Document Type: Article

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