Determination of essential amino acids in human serum by a targeting method based on automated SPE-LC-MS/MS: Discrimination between artherosclerotic patients

Journal of Pharmaceutical and Biomedical Analysis

Volumn 70, Issue , 2012, Pages 476-484

  Calderon Santiago M ^a   Priego Capote, F ^a   Galache Osuna, J G ^b   Luque de Castro, M D ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

Author keywords

Atherosclerosis; Automated SPE; Essential amino acids; Obesity; Serum; Targeting metabolomics analysis

Indexed keywords

ESSENTIAL AMINO ACID; ISOLEUCINE; LEUCINE; LYSINE; METHIONINE; PHENYLALANINE; SORBENT; THREONINE; TRYPTOPHAN; VALINE;

ACCURACY; ACUTE HEART INFARCTION; AGED; ARTICLE; ATHEROSCLEROSIS; CATHETERIZATION; CHEMOMETRIC ANALYSIS; CORONARY ARTERY DISEASE; FEMALE; GENDER; HUMAN; HYPERCHOLESTEROLEMIA; ISCHEMIA; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SENSITIVITY ANALYSIS; SMOKING; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

AGED; AMINO ACIDS, ESSENTIAL; ANGINA, STABLE; AUTOMATION, LABORATORY; BIOLOGICAL MARKERS; CALIBRATION; CARDIAC CATHETERIZATION; CHROMATOGRAPHY, LIQUID; CORONARY ARTERY DISEASE; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; LIMIT OF DETECTION; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84866251432     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.06.033     Document Type: Article

References (25)

1. Wu G.Y. Amino acids: metabolism, functions, and nutrition. Amino Acids 2009, 37:1-17.
2. Misra M.K., Sarwat M., Bhakuni P., Tuteja R., Tuteja N. Oxidative stress and ischemic myocardial syndromes. Med. Sci. Monit. 2009, 15:209-219.
3. Mitra S., Goyal T., Mehta J.L. Oxidized LDL, LOX-1 and atherosclerosis. Cardiovasc. Drugs Ther. 2011, 25:419-429.
4. Sugamura K., Keaney J.F. Reactive oxygen species in cardiovascular disease. Free Radic. Biol. Med. 2011, 51:978-992.
5. Stocker R., Keaney J.F. Role of oxidative modifications in atherosclerosis. Physiol. Rev. 2004, 84:1381-1478.
6. Madamanchi N.R., Hakim Z.S., Runge M.S. Oxidative stress in atherogenesis and arterial thrombosis: the disconnect between cellular studies and clinical outcomes. J. Thromb. Haemost. 2005, 3:254-267.
7. Elisaf M. The treatment of coronary heart disease: an update-Part 1. An overview of the risk factors for cardiovascular disease. Curr. Med. Res. Opin. 2001, 17:18-26.
8. Hill J.O., Peters J.C., Catenacci V.A., Wyatt H.R. International strategies to address obesity. Obes. Rev. 2008, 9:41-47.
9. She P.X., Van Horn C., Reid T., Hutson S.M., Cooney R.N., Lynch C.J. Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism. Am. J. Physiol. Endocrinol. Metab. 2007, 293:1552-1563.
10. Yao H., Shi P.Y., Zhang L., Fan X.H., Shao Q., Cheng Y.Y. Untargeted metabolic profiling reveals potential biomarkers in myocardial infarction and its application. Mol. Biosyst. 2010, 6:1061-1070.
11. Lewis G.D., Wei R., Liu E., Yang E., Shi X., Martinovic M., Farrell L., Asnani A., Cyrille M., Ramanathan A., Shaham O., Berriz G., Lowry P.A., Palacios I.F., Tasan M., Roth F.P., Min J.Y., Baumgartner C., Keshishian H., Addona T., Mootha V.K., Rosenzweig A., Carr S.A., Fifer M.A., Sabatine M.S., Gerszten R.E. Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury. J. Clin. Invest. 2008, 118:3503-3512.
12. Li Y., Tang A.G., Mu S. HPLC-FLD determination of serum aromatic amino acids: application in chronic kidney disease patients. Clin. Chim. Acta 2011, 412:1032-1035.
13. He Y.Y., Zhao L.J., Yuan H.Y., Xu Z.M., Tang Y., Xiao D., Choi M.M.F. HPLC with in-capillary optical fiber laser-induced fluorescence detection of picomolar amounts of amino acids by precolumn fluorescence derivatization with fluorescein isothiocyanate. Chromatographia 2011, 74:541-547.
14. Song L.J., Guo Z.P., Chen Y. One-pot labeling-based capillary zone electrophoresis for separation of amino acid mixture and assay of biofluids. Anal. Chim. Acta 2011, 703:257-263.
15. Shangguan D.H., Zhao Y.X., Han H.W., Zhao R., Liu G.Q. Derivatization and fluorescence detection of amino acids and peptides with 9-fluorenylmethyl chloroformate on the surface of a solid adsorbent. Anal. Chem. 2001, 73:2054-2057.
16. Strieglerova L., Kuban P., Bocek P. Electromembrane extraction of amino acids from body fluids followed by capillary electrophoresis with capacitively coupled contactless conductivity detection. J. Chromatogr. A 2011, 1218:6248-6255.
17. Tak Y.H., Somsen G.W., de Jong G.J. Optimization of dynamic pH junction for the sensitive determination of amino acids in urine by capillary electrophoresis. Anal. Bioanal. Chem. 2011, 401:3275-3281.
18. LeBoucher J., Charret C., CoudrayLucas C., Giboudeau J., Cynober L. Amino acid determination in biological fluids by automated ion-exchange chromatography: performance of Hitachi L-8500A. Clin. Chem. 1997, 43:1421-1428.
19. Ackermans M.T., Klieverik L.P., Ringeling P., Endert E., Kalsbeek A., Fliers E. An online solid-phase extraction-liquid chromatography-tandem mass spectrometry method to study the presence of thyronamines in plasma and tissue and their putative conversion from (13)C(6)-thyroxine. J. Endocrinol. 2010, 206:327-334.
20. Jagerdeo E., Montgornery M.A., Sibum M., Sasaki T.A., LeBeau M.A. Rapid analysis of cocaine and metabolites in urine using a completely automated solid-phase extraction-high-performance liquid chromatography-tandem mass spectrometry method. J. Anal. Toxicol. 2008, 32:570-576.
21. Jagerdeo E., Montgomery M.A., LeBeau M.A., Sibum M. An automated SPE/LC/MS/MS method for the analysis of cocaine and metabolites in whole blood. J. Chromatogr. B 2008, 874:15-20.
22. Massart D.L., Vanderginstre B.G.M., Buydens L.M.C., De Jong S., Lewi P.J., Smeyers-Verbeke J. Handbook of Chemometrics and Qualimetrics. Part A 1997, Elsevier, Amsterdam. 1st edition.
23. Cynober L.A. Plasma amino acid levels with a note on membrane transport: characteristics, regulation, and metabolic significance. Nutrition 2002, 18:761-766.
24. Wernerman J., Rooyackers O. Methods, who cares?. Clin. Nutr. 2000, 19:145-146.
25. Norrelund H., Wiggers H., Halbirk M., Frystyk J., Flyvbjerg A., Botker H.E., Schmitz O., Jorgensen J.O.L., Christiansen J.S., Moller N. Abnormalities of whole body protein turnover, muscle metabolism and levels of metabolic hormones in patients with chronic heart failure. J. Intern. Med. 2006, 260:11-21.