Genetically driven target tissue overexpression of CD40: A novel mechanism in autoimmune disease

Journal of Immunology

Volumn 189, Issue 6, 2012, Pages 3043-3053

  Huber, Amanda K ^a   Finkelman, Fred D ^b   Li, Cheuk Wun ^a   Concepcion, Erlinda ^a   Smith, Eric ^c   Jacobson, Eric ^c   Latif, Rauf ^b   Keddache, Mehdi ^d   Zhang, Weijia ^a   Tomer, Yaron ^a,b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 6; INTERLEUKIN 8; THYROID ANTIBODY; THYROXINE; TRANSCRIPTOME; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD40 GENE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE MODEL; DISEASE SEVERITY; FEMALE; GENE; GENE DELETION; GENE OVEREXPRESSION; GRAVES DISEASE; INNATE IMMUNITY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TARGET ORGAN; THYROID CELL; THYROID GLAND;

ANIMALS; ANTIGENS, CD40; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE TARGETING; GRAVES DISEASE; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PRIMARY CELL CULTURE; RADIATION CHIMERA; RECEPTORS, THYROTROPIN; THYROID GLAND;

EID: 84866184305     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200311     Document Type: Article

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