Intensification of doxorubicin-related oxidative stress in the heart by hypothyroidism is not related to the expression of cytochrome P450 NADPH-reductase and inducible nitric oxide synthase, as well as activity of xanthine oxidase

Oxidative Medicine and Cellular Longevity

Volumn , Issue , 2012, Pages

  Dudka, Jaroslaw ^a   Burdan, Franciszek ^a   Korga, Agnieszka ^a   Iwan, Magdalena ^a   Madej Czerwonka, Barbara ^a   Cendrowska Pinkosz, Monika ^a   Korobowicz Markiewicz, Agnieszka ^a   Jodlowska Jedrych, Barbara ^a   Matysiak, Wlodzimierz ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL GROUPS; CARDIOTOXICITY; CYTOCHROME P450; DOXORUBICIN; DRUG ADMINISTRATION; GLUTATHIONES; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPID PEROXIDATION; METHIMAZOLE; OXIDATIVE DAMAGE; SYNTHASES; XANTHINE OXIDASE;

ENZYMES; HEART; NITRIC OXIDE; RATS;

OXIDATIVE STRESS;

CARBONYL DERIVATIVE; CYTOCHROME P450 NADPH REDUCTASE; CYTOCHROME P450 REDUCTASE; DOXORUBICIN; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; THIAMAZOLE; UNCLASSIFIED DRUG; XANTHINE OXIDASE; ANTINEOPLASTIC ANTIBIOTIC; ANTITHYROID AGENT; LIOTHYRONINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME ACTIVITY; HYPOTHYROIDISM; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; ANIMAL; BLOOD; DNA DAMAGE; DRUG EFFECT; HEART; HEART MUSCLE; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALIA; RATTUS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTITHYROID AGENTS; DNA DAMAGE; DOXORUBICIN; HEART; HYPOTHYROIDISM; MALE; METHIMAZOLE; MYOCARDIUM; NADPH-FERRIHEMOPROTEIN REDUCTASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, WISTAR; TRIIODOTHYRONINE; XANTHINE OXIDASE;

EID: 84866181143     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2012/139327     Document Type: Article

References (42)

1. Minotti G., Menna P., Salvatorelli E., Cairo G., Gianni L., Anthracyclines: molecular advances and pharmacologie developments in antitumor activity and cardiotoxicity. Pharmacological Reviews 2004 56 2 185 229 2-s2.0-2642566088 10.1124/pr.56.2.6 (Pubitemid 38720829)
2. Ferreira A. L. A., Matsubara L. S., Matsubara B. B., Anthracycline- induced cardiotoxicity. Cardiovascular and Hematological Agents in Medicinal Chemistry 2008 6 4 278 281 2-s2.0-54949128285 10.2174/187152508785909474
3. Ashour A. E., Sayed-Ahmed M. M., Abd-Allah A. R., Korashy H. M., Maayah Z. H., Alkhalidi H., Mubarak M., Alhaider A., Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats. Oxidative Medicine and Cellular Longevity 2012 2012 13 10.1155/2012/434195 434195
4. Dudka J., Burdan F., Korga A., Dyndor K., Syroka I., Zieba J., Lewkowicz D., Korobowicz-Markiewicz A., The diagnosis of anthracycline-induced cardiac damage and heart failure. Postepy Higieny i Medycyny Dowiadczalnej 2009 63 225 233 2-s2.0-70350769387
5. Zhang Y. W., Shi J., Li Y. J., Wei L., Cardiomyocyte death in doxorubicin-induced cardiotoxicity. Archivum Immunologiae et Therapiae Experimentalis 2009 57 435 445
6. Sardão V. A., Oliveira P. J., Holy J., Oliveira C. R., Wallace K. B., Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biology and Toxicology 2009 25 3 227 243 2-s2.0-67349167673 10.1007/s10565-008-9070-1
7. Berthiaume J. M., Wallace K. B., Persistent alterations to the gene expression profile of the heart subsequent to chronic doxorubicin treatment. Cardiovascular Toxicology 2007 7 3 178 191 2-s2.0-35348847091 10.1007/s12012-007-0026-0 (Pubitemid 47575003)
8. Tokarska-Schlattner M., Wallimann T., Schlattner U., Alterations in myocardial energy metabolism induced by the anti-cancer drug doxorubicin. Comptes Rendus Biologies 2006 329 9 657 668 2-s2.0-33747814448 10.1016/j.crvi.2005.08.007 (Pubitemid 44283720)
9. Dudka J., The role of reactive oxygen and nitrogen species in calcium and iron homeostasis dysregulation in anthracycline cardiotoxicity. Postepy Higieny i Medycyny Dowiadczalnej 2006 60 241 247 2-s2.0-33846105088
10. Mihm M. J., Yu F., Weinstein D. M., Reiser P. J., Bauer J. A., Intracellular distribution of peroxynitrite during doxorubicin cardiomyopathy: Evidence for selective impairment of myofibrillar creatine kinase. British Journal of Pharmacology 2002 135 3 581 588 2-s2.0-0036177397 (Pubitemid 34177635)
11. Surmeli N. B., Litterman N. K., Miller A. F., Groves J. T., Peroxynitrite mediates active site tyrosine nitration in manganese superoxide dismutase. evidence of a role for the carbonate radical anion. Journal of the American Chemical Society 2010 132 48 17174 17185 2-s2.0-78650119986 10.1021/ja105684w
12. Deng S., Kruger A., Kleschyov A. L., Kalinowski L., Daiber A., Wojnowski L., Gp91phox-containing NAD(P)H oxidase increases superoxide formation by doxorubicin and NADPH. Free Radical Biology and Medicine 2007 42 4 466 473 2-s2.0-33846517425 10.1016/j.freeradbiomed.2006.11.013 (Pubitemid 46162116)
13. Bachur N. R., Gordon S. L., Gee M. V., A general mechanism for microsomal activation of quinone anticancer agents to free radicals. Cancer Research 1978 38 6 1745 1750 2-s2.0-0018194637 (Pubitemid 8349723)
14. Fogli S., Nieri P., Breschi M. C., The role of nitric oxide in anthracycline toxicity and prospects for pharmacologic prevention of cardiac damage. FASEB Journal 2004 18 6 664 675 2-s2.0-1842559586 10.1096/fj.03-0724rev (Pubitemid 38451788)
15. Mukhopadhyay P., Rajesh M., Bátkai S., Kashiwaya Y., Haskó G., Liaudet L., Szabó C., Pacher P., Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro. American Journal of Physiology 2009 296 5 H1466 H1483 2-s2.0-66149110905 10.1152/ajpheart.00795.2008
16. Gustafson D. L., Swanson J. D., Pritsos C. A., Role fo xanthine oxidase in the potentiation of doxorubicin-induced cardiotoxicity by mitomycin C. Cancer Communications 1991 3 9 299 304 2-s2.0-0025925196
17. Davies K. J. A., Doroshow J. H., Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase. Journal of Biological Chemistry 1986 261 7 3060 3067 2-s2.0-0022967083 (Pubitemid 17204909)
18. Tee M. K., Huang N., Damm I., Miller W. L., Transcriptional regulation of the human p450 oxidoreductase gene: Hormonal regulation and influence of promoter polymorphisms. Molecular Endocrinology 2011 25 5 715 731 2-s2.0-79955787007 10.1210/me.2010-0236
19. Li H. C., Liu D., Waxman D. J., Transcriptional induction of hepatic NADPH: cytochrome P450 oxidoreductase by thyroid hormone. Molecular Pharmacology 2001 59 5 987 995 2-s2.0-0035032022 (Pubitemid 32381577)
20. Ram P. A., Waxman D. J., Thyroid hormone stimulation of NADPH P450 reductase expression in liver and extrahepatic tissues. Regulation by multiple mechanisms. Journal of Biological Chemistry 1992 267 5 3294 3301 2-s2.0-0026726737
21. Virdis A., Colucci R., Fornai M., Polini A., Daghini E., Duranti E., Ghisu N., Versari D., Dardano A., Blandizzi C., Taddei S., Tacca M. D., Monzani F., Inducible nitric oxide synthase is involved in endothelial dysfunction of mesenteric small arteries from hypothyroid rats. Endocrinology 2009 150 2 1033 1042 2-s2.0-59649119849 10.1210/en.2008-1112
22. Bergmeyer H. U., Gawehn K., Grassel M. W., 2nd, Methods of Enzymatic Analysis 1974 1 Edited by H. U. Bergmeyer New York, NY, USA Academic Press
23. Garner A. P., Paine M. J. I., Rodriguez-Crespo I., Chinje E. C., De Montellano P. O., Stratford I. J., Tew D. G., Wolf C. R., Nitric oxide synthases catalyze the activation of redox cycling and bioreductive anticancer agents. Cancer Research 1999 59 8 1929 1934 2-s2.0-0033561524 (Pubitemid 29186167)
24. Vásquez-Vivar J., Martasek P., Hogg N., Masters B. S. S., Pritchard K. A. Jr., Kalyanaraman B., Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin. Biochemistry 1997 36 38 11293 11297 2-s2.0-19244383998 10.1021/bi971475e (Pubitemid 27408610)
25. Chattopadhyay S., Zaidi G., Das K., Chainy G. B. N., Effects of hypothyroidism induced by 6-n-propylthiouracil and its reversal by T3 on rat heart superoxide dismutase, catalase and lipid peroxidation. Indian Journal of Experimental Biology 2003 41 8 846 849 2-s2.0-0043199636 (Pubitemid 36953555)
26. Jain M., Brenner D. A., Cui L., Lim C. C., Wang B., Pimentel D. R., Koh S., Sawyer D. B., Leopold J. A., Handy D. E., Loscalzo J., Apstein C. S., Liao R., Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes. Circulation Research 2003 93 2 e9 16 2-s2.0-0042233494
27. Lombardi A., Beneduce L., Moreno M., Diano S., Colantuoni V., Ursini M. V., Lanni A., Goglia F., 3,5-Diiodo-L-thyronine regulates glucose-6-phosphate dehydrogenase activity in the rat. Endocrinology 2000 141 5 1729 1734 2-s2.0-0034455323 10.1210/en.141.5.1729 (Pubitemid 32274403)
28. Palmeira C. M., Serrano J., Kuehl D. W., Wallace K. B., Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin. Biochimica et Biophysica Acta 1997 1321 2 101 106 2-s2.0-0030880285 10.1016/S0005-2728(97)00055-8 (Pubitemid 27390500)
29. Fadillioglu E., Oztas E., Erdogan H., Yagmurca M., Sogut S., Ucar M., Irmak M. K., Protective effects of caffeic acid phenethyl ester on doxorubicin-induced cardiotoxicity in rats. Journal of Applied Toxicology 2004 24 1 47 52 2-s2.0-0842344493 10.1002/jat.945 (Pubitemid 38181541)
30. Mansour M. A., El-Din A. G., Nagi M. N., Al-Shabanah O. A., Al-Bekairi A. M., N ω -Nitro-L-Arginine Methylester Ameliorates Myocardial Toxicity Induced by Doxorubicin. Journal of Biochemistry and Molecular Biology 2003 36 6 593 596 2-s2.0-0942289825 (Pubitemid 38142684)
31. Bolaman Z., Cicek C., Kadikoylu G., Barutca S., Serter M., Yenisey C., Alper G., The protective effects of amifostine on adriamycin-induced acute cardiotoxicity in rats. Tohoku Journal of Experimental Medicine 2005 207 4 249 253 2-s2.0-29144449476 10.1620/tjem.207.249 (Pubitemid 41799998)
32. Sun X., Kang Y. J., Prior increase in metallothionein levels is required to prevent doxorubicin cardiotoxicity. Experimental Biology and Medicine 2002 227 8 652 657 2-s2.0-0036735062
33. Li T., Danelisen I., Singal P. K., Early changes in myocardial antioxidant enzymes in rats treated with adriamycin. Molecular and Cellular Biochemistry 2002 232 1-2 19 26 2-s2.0-0036010747 10.1023/A:1014862912783 (Pubitemid 34413877)
34. Grune T., Reinheckel T., Davies K. J. A., Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. Journal of Biological Chemistry 1996 271 26 15504 15509 2-s2.0-0029984892 10.1074/jbc.271.26.15504 (Pubitemid 26225322)
35. Grune T., Reinheckel T., Joshi M., Davies K. J. A., Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome. Journal of Biological Chemistry 1995 270 5 2344 2351 2-s2.0-0028912676 10.1074/jbc.270.5.2344
36. Siems W. G., Zollner H., Grune T., Esterbauer H., Metabolic fate of 4-hydroxynonenal in hepatocytes: 1,4-dihydroxynonene is not the main product. Journal of Lipid Research 1997 38 3 612 622 2-s2.0-0030986162 (Pubitemid 27166704)
37. Przybyszewski W. M., Kasperczyk J., Stoklosa K., Bkhiyan A., DNA damage induced by products of lipid peroxidation. Postepy Higieny i Medycyny Dowiadczalnej 2005 59 75 81
38. Marnett L. J., Riggins J. N., West J. D., Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. Journal of Clinical Investigation 2003 111 5 583 593 2-s2.0-0037373455 10.1172/JCI200318022 (Pubitemid 36278574)
39. Marnett L. J., Lipid peroxidation-DNA damage by malondialdehyde. Mutation Research 1999 424 1-2 83 95 2-s2.0-0033535371 10.1016/S0027-5107(99)00010-X (Pubitemid 29101610)
40. Moller P., Wallin H., Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation product. Mutation Research 1998 410 3 271 290 2-s2.0-0032101840 10.1016/S1383-5742(97)00041-0 (Pubitemid 28267163)
41. Dalle-Donne I., Rossi R., Giustarini D., Milzani A., Colombo R., Protein carbonyl groups as biomarkers of oxidative stress. Clinica Chimica Acta 2003 329 1-2 23 38 2-s2.0-0037363715 10.1016/S0009-8981(03)00003-2 (Pubitemid 36187411)
42. Flores-Morales A., Gullberg H., Fernandez L., Ståhlberg N., Lee N. H., Vennström B., Norstedt G., Patterns of liver gene expression governed by TR β Molecular Endocrinology 2002 16 6 1257 1268 2-s2.0-0035989243 10.1210/me.16.6.1257 (Pubitemid 34621074)