Prior increase in metallothionein levels is required to prevent doxorubicin cardiotoxicity

Experimental Biology and Medicine

Volumn 227, Issue 8, 2002, Pages 652-657

  Sun, Xiuhua ^a   James Kang, Y ^a,b  

^a University of Louisville School of Medicine   (United States)

^b JEWISH HOSPITAL   (United States)

Author keywords

Cardiomyopathy; Creatine phosphokinase; Doxorubicin; Transgenic mice; Ultrastructural alterations

Indexed keywords

CREATINE KINASE; DOXORUBICIN; GLUTATHIONE; METALLOTHIONEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; ELECTRON MICROSCOPY; HEART PROTECTION; LIPID PEROXIDATION; MALE; NONHUMAN; PATHOPHYSIOLOGY; RAT; TRANSGENIC MOUSE;

ANIMALS; CARDIOMYOPATHIES; CREATINE KINASE; CREATINE KINASE, MB FORM; DOXORUBICIN; DRUG ADMINISTRATION SCHEDULE; GENE EXPRESSION; GENES, SYNTHETIC; GLUTATHIONE; HUMANS; ISOENZYMES; LIPID PEROXIDATION; MALE; METALLOTHIONEIN; MICE; MICE, TRANSGENIC; ORGAN SPECIFICITY; OXIDATIVE STRESS; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; TIME FACTORS;

ANIMALIA; MUS MUSCULUS;

EID: 0036735062     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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