A review of Titanium Zirconium (TiZr) alloys for use in endosseous dental implants

Materials

Volumn 5, Issue 8, 2012, Pages 1348-1360

  Michelle Grandin, H ^a   Berner, Simon ^b   Dard, Michel ^b,c  

^a Institut Straumann AG ^*

^b INSTITUT STRAUMANN AG   (Switzerland)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

Clinical; Endosseous dental implant; In vitro; In vivo; Reduced or small diameter implant; Titanium zirconium alloy; TiZr

Indexed keywords

CLINICAL; CLINICAL STUDY; DENTAL IMPLANT APPLICATIONS; HIGH STRENGTH; IN-VITRO; IN-VIVO; OSSEOINTEGRATION; TI-ZR ALLOYS; TITANIUM IMPLANTS; TIZR;

ANIMALS; BINARY ALLOYS; BIOCOMPATIBILITY; CORROSION RESISTANCE; DENTAL PROSTHESES; HIGH STRENGTH ALLOYS; TITANIUM; ZIRCONIUM;

TITANIUM ALLOYS;

EID: 84866178341     PISSN: None     EISSN: 19961944     Source Type: Journal    
DOI: 10.3390/ma5081348     Document Type: Article

References (47)

1. Vannoort, R. Titanium-The implant material of today. J. Mater. Sci. 1987, 22, 3801-3811.
2. Steinemann, S.G. Titanium-The material of choice? Periodontology 2000 1998, 17, 7-21.
3. Williams, D.F. Titanium for medical applications. In Titanium in Medicine; Brunette, D., Tengvall, P., Textor, M., Thomson, P., Eds.; Springer: Berlin, Germany, 2001; pp. 14-24.
4. Branemark, P.I. Osseointegration and its experimental background. J. Prosthet. Dent. 1983, 50, 399-410.
5. Odman, J.; Lekholm, U.; Jemt, T.; Branemark, P.I.; Thilander, B. Osseointegrated titanium implants-A new approach in orthodontic treatment. Eur. J. Orthodont. 1988, 10, 98-105.
6. Al-Nawas, B.; Bragger, U.; Meijer, H.J.; Naert, I.; Persson, R.; Perucchi, A.; Quirynen, M.; Raghoebar, G.M.; Reichert, T.E.; Romeo, E.; et al. A double-blind randomized controlled trial (RCT) of titanium-13zirconium versus titanium grade IV small-diameter bone level implants in edentulous mandibles-Results from a 1-year observation period. Clin. Implant. Dent. Relat. Res. 2011. doi: 10.1111/j.1708-8208.2010.00324.x. Available online: http://onlinelibrary.wiley.com/doi/10.1111/j.1708-8208.2010.00324.x/abstract (accessed on 30 July 2012).
7. Romeo, E.; Lops, D.; Amorfini, L.; Chiapasco, M.; Ghisolfi, M.; Vogel, G. Clinical and radiographic evaluation of small-diameter (3.3 mm) implants followed for 1-7 years: A longitudinal study. Clin. Oral Implants Res. 2006, 17, 139-148.
8. Zinsli, B.; Sagesser, T.; Mericske, E.; Mericske-Stern, R. Clinical evaluation of small-diameter ITI implants: A prospective study. Int. J. Oral Maxillofac. Implants 2004, 19, 92-99.
9. Allum, S.R.; Tomlinson, R.A.; Joshi, R. The impact of loads on standard diameter, small diameter and mini implants: A comparative laboratory study. Clin. Oral Implants Res. 2008, 19, 553-559.
10. Schwarz, M.S. Mechanical complications of dental implants. Clin. Oral Implants Res. 2000, 11, 156-158.
11. Parr, G.R.; Gardner, L.K.; Toth, R.W. Titanium-The mystery metal of implant dentistry-Dental materials aspects. J. Prosthet. Dent. 1985, 54, 410-414. Materials 2012, 5 1358
12. Olmedo, D.G.; Tasat, D.R.; Duffo, G.; Guglielmotti, M.B.; Cabrini, R.L. The issue of corrosion in dental implants: A review. Acta Odontol. Latinoam. 2009, 22, 3-9.
13. Khan, M.A.; Williams, R.L.; Williams, D.F. Conjoint corrosion and wear in titanium alloys. Biomaterials 1999, 20, 765-772.
14. Okazaki, Y.; Gotoh, E. Comparison of metal release from various metallic biomaterials in vitro. Biomaterials 2005, 26, 11-21.
15. Li, Y.; Wong, C.; Xiong, J.; Hodgson, P.; Wen, C. Cytotoxicity of titanium and titanium alloying elements. J. Dent. Res. 2010, 89, 493-497.
16. Kobayashi, E.; Doi, H.; Yoneyama, T.; Hamanaka, H.; Gibson, I.R.; Best, S.M.; Shelton, J.C.; Bonfield, W. Influence of aging heat treatment on mechanical properties of biomedical Ti-Zr based ternary alloys containing niobium. J. Mater. Sci. Mater. Med. 1998, 9, 625-630.
17. Bernhard, N.; Berner, S.; De Wild, M.; Wieland, M. The binary TiZr alloy-A newly developed Ti alloy for use in dental implants. Forum Implantol. 2009, 5, 30-39.
18. Kim, T.I.; Han, J.H.; Lee, I.S.; Lee, K.H.; Shin, M.C.; Choi, B.B. New titanium alloys for biomaterials: a study of mechanical and corrosion properties and cytotoxicity. Biomed. Mater. Eng. 1997, 7, 253-263.
19. Zhang, Y.M.; Chai, F.; Hornez, J.C.; Li, C.L.; Zhao, Y.M.; Traisnel, M.; Hildebrand, H.F. The corrosion and biological behaviour of titanium alloys in the presence of human lymphoid cells and MC3T3-E1 osteoblasts. Biomed. Mater. 2009, 4, doi: 10.1088/1748-6041/4/1/015004.
20. Naganawa, T.; Ishihara, Y.; Iwata, T.; Koide, A.; Ohguchi, M.; Ohguchi, Y.; Murase, Y.; Kamei, H.; Sato, N.; Mizuno, M.; Noguchi, T. In vitro biocompatibility of a new titanium-29niobium-13tantalum-4.6zirconium alloy with osteoblast-like MG63 cells. J. Periodontol. 2004, 75, 1701-1707.
21. Ikarashi, Y.; Toyoda, K.; Kobayashi, E.; Doi, H.; Yoneyama, T.; Hamanaka, H.; Tsuchiya, T. Improved biocompatibility of titanium-zirconium (Ti-Zr) alloy: Tissue reaction and sensitization to Ti-Zr alloy compared with pure Ti and Zr in rat implantation study. Mater. Trans. 2005, 46, 2260-2267.
22. Buser, D. Titanium for dental applications (II): Implants with roughened surfaces. In Titanium in Medicine; Brunette, D., Tengvall, P., Textor, M., Thomson, P., Eds.; Springer: Berlin, Germany, 2001; pp. 232-239.
23. Cochran, D.L.; Nummikoski, P.V.; Higginbottom, F.L.; Hermann, J.S.; Makins, S.R.; Buser, D. Evaluation of an endosseous titanium implant with a sandblasted and acid-etched surface in the canine mandible: Radiographic results. Clin. Oral Implants Res. 1996, 7, 240-252.
24. Buser, D.; Nydegger, T.; Oxland, T.; Cochran, D.L.; Schenk, R.K.; Hirt, H.P.; Snetivy, D.; Nolte, L.P. Interface shear strength of titanium implants with a sandblasted and acid-etched surface: A biomechanical study in the maxilla of miniature pigs. J. Biomed. Mater. Res. 1999, 45, 75-83.
25. Roccuzzo, M.; Bunino, M.; Prioglio, F.; Bianchi, S.D. Early loading of sandblasted and acid-etched (SLA) implants: A prospective split-mouth comparative study-One-year results. Clin. Oral Implants Res. 2001, 12, 572-578.
26. Bornstein, M.M.; Lussi, A.; Schmid, B.; Belser, U.C.; Buser, D. Early loading of nonsubmerged titanium implants with a sandblasted and acid-etched (SLA) surface: 3-Year results of a Materials 2012, 5 1359 prospective study in partially edentulous patients. Int. J. Oral Maxillofac. Implants 2003, 18, 659-666.
27. Fischer, K.; Stenberg, T. Prospective 10-year cohort study based on a randomized controlled trial (RCT) on implant-supported full-arch maxillary prostheses. Part 1: Sandblasted and acid-etched implants and mucosal tissue. Clin. Implant. Dent. Relat. Res. 2011, doi: 10.1111/j.1708-8208.2011.00389.x. Available online: http://onlinelibrary.wiley.com/doi/10.1111/j.1708-8208.2011.00389.x/abstract (accessed on 30 July 2012)
28. Zhao, G.; Schwartz, Z.; Wieland, M.; Rupp, F.; Geis-Gerstorfer, J.; Cochran, D.L.; Boyan, B.D. High surface energy enhances cell response to titanium substrate microstructure. J. Biomed. Mater. Res. 2005, 74A, 49-58.
29. Sista, S.; Wen, C.; Hodgson, P.D.; Pande, G. The influence of surface energy of titanium-zirconium alloy on osteoblast cell functions in vitro. J. Biomed. Mater. Res. 2011, 97A, 27-36.
30. Rupp, F.; Scheideler, L.; Olshanska, N.; De Wild, M.; Wieland, M.; Geis-Gerstorfer, J. Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces. J. Biomed. Mater. Res. 2006, 76A, 323-334.
31. Buser, D.; Broggini, N.; Wieland, M.; Schenk, R.K.; Denzer, A.J.; Cochran, D.L.; Hoffmann, B.; Lussi, A.; Steinemann, S.G. Enhanced bone apposition to a chemically modified SLA titanium surface. J. Dent. Res. 2004, 83, 529-533.
32. Schwarz, F.; Herten, M.; Sager, M.; Wieland, M.; Dard, M.; Becker, J. Bone regeneration in dehiscence-type defects at chemically modified (SLActive((R))) and conventional SLA titanium implants: A pilot study in dogs. J. Clin. Periodontol. 2007, 34, 78-86.
33. Zollner, A.; Ganeles, J.; Korostoff, J.; Guerra, F.; Krafft, T.; Bragger, U. Immediate and early non-occlusal loading of Straumann implants with a chemically modified surface (SLActive) in the posterior mandible and maxilla: Interim results from a prospective multicenter randomized-controlled study. Clin. Oral Implants Res. 2008, 19, 442-450.
34. Wennerberg, A.; Svanborg, L.M.; Berner, S.; Andersson, M. Spontaneously formed nanostructures on titanium surfaces. Clin. Oral Implants Res. 2012, doi: 10.1111/j.1600-0501.2012.02429.x. Avaliable online: http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0501.2012.02429.x/abstract (accessed on 30 July 2012).
35. Kobayashi, E.; Matsumoto, S.; Doi, H.; Yoneyama, T.; Hamanaka, H. Mechanical properties of the binary titanium-zirconium alloys and their potential for biomedical materials. J. Biomed. Mater. Res. 1995, 29, 943-950.
36. Gottlow, J.; Dard, M.; Kjellson, F.; Obrecht, M.; Sennerby, L. Evaluation of a new titanium-zirconium dental implant: A biomechanical and histological comparative study in the mini pig. Clin. Implant Dent. Relat. Res. 2012, 14, 538-545.
37. Saulacic, N.; Bosshardt, D.D.; Bornstein, M.M.; Berner, S.; Buser, D. Bone apposition to a titanium-zirconium alloy implant, as compared to two other titanium-containing implants. Eur. Cells Mater. 2012, 23, 273-288.
38. Shibata, N.; Okuno, O. Bone and fibrous tissue ingrowth into the porous Zr-Ti implants. Dent. Mater. J. 1987, 6, 185-200. Materials 2012, 5 1360
39. Thoma, D.S.; Jones, A.A.; Dard, M.; Grize, L.; Obrecht, M.; Cochran, D.L. Tissue integration of a new titanium-zirconium dental implant: A comparative histologic and radiographic study in the canine. J. Periodontol. 2011, 82, 1453-1461.
40. Barter, S.; Stone, P.; Bragger, U. A pilot study to evaluate the success and survival rate of titanium-zirconium implants in partially edentulous patients: Results after 24 months of follow-up. Clin. Oral Implants Res. 2012, 23, 873-881.
41. Chiapasco, M.; Casentini, P.; Zaniboni, M.; Corsi, E.; Anello, T. Titanium-zirconium alloy narrow-diameter implants (Straumann Roxolid®) for the rehabilitation of horizontally deficient edentulous ridges: Prospective study on 18 consecutive patients. Clin. Oral Implants Res. 2011, doi: 10.1111/j.1600-0501.2011.02296.x. Avaliable online: http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0501.2011.02296.x/abstract (accessed on 30 July 2012).
42. Steinemann, S. Binary titanium-zirconium alloy for surgical implants and a suitable manufacturing process. US Patent 8,168,012, 1 May 2012.
43. Implants for surgery-Metallic materials-Part 2: Unalloyed titanium (ISO 5832-2:1999); DIN ISO 5832-2:2012-08; International Organization for Standardization: Geneva, The Switzerland, 2012
44. Implants for surgery-Metallic materials-Part 3: Wrought titanium 6-aluminium 4-vanadium alloy (ISO 5832-3:1996); DIN EN ISO 5832-3:2012-08; International Organization for Standardization: Geneva, The Switzerland, 2012
45. Implants for surgery-Metallic materials-Part 11: Wrought titanium 6-aluminium 7-niobium alloy (ISO 5832-11:1994); DIN ISO 5832-11:2001-04; International Organization for Standardization: Geneva, The Switzerland, 2001
46. Chen, X.; Nouri, A.; Li, Y.; Lin, J.; Hodgson, P.D.; Wen, C. Effect of surface roughness of Ti, Zr, and TiZr on apatite precipitation from simulated body fluid. Biotechnol. Bioeng. 2008, 101, 378-387.
47. Freilich, M.; Wen, B.; Shafer, D.; Schleier, P.; Dard, M.; Pendrys, D.; Ortiz, D.; Kuhn, L. Implant-guided vertical bone growth in the mini-pig. Clin. Oral Implants Res. 2012, 23, 751-757.