Biofilm formation in long-term central venous catheters in children with cancer: A randomized controlled open-labelled trial of taurolidine versus heparin

APMIS

Volumn 120, Issue 10, 2012, Pages 794-801

  Handrup, Mette Møller ^a   Fuursted, Kurt ^a   Funch, Peter ^b   Møller, Jens Kjølseth ^a   Schrøder, Henrik ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Bacteraemia; Biofilm; Catheter related infection; Paediatric; Taurolidine

Indexed keywords

HEPARIN; TAUROLIDINE;

ADOLESCENT; ADULT; ARTICLE; BIOFILM; BLOODSTREAM INFECTION; CATHETER INFECTION; CENTRAL VENOUS CATHETER; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INFANT; MALE; NEOPLASM; NEWBORN; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SCHOOL CHILD;

EID: 84866162907     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2012.02910.x     Document Type: Article

References (29)

1. Flynn PM Diagnosis and management of central venous catheter-related bloodstream infections in pediatric patients. Pediatr Infect Dis J 2009;28:1016-7.
2. Raad I, Hanna H, Maki D Intravascular catheter-related infections: advances in diagnosis, prevention, and management. Lancet Infect Dis 2007;7:645-57.
3. Raad I, Costerton W, Sabharwal U, Sacilowski M, Anaissie E, Bodey GP Ultrastructural analysis of indwelling vascular catheters: a quantitative relationship between luminal colonization and duration of placement. J Infect Dis 1993;168:400-7.
4. Costerton JW, Stewart PS, Greenberg EP Bacterial biofilms: a common cause of persistent infections. Science 1999;284:1318-22.
5. Donlan RM Biofilms: microbial life on surfaces. Emerg Infect Dis 2002;8:881-90.
6. Rupp ME, Lisco SJ, Lipsett PA, Perl TM, Keating K, Civetta JM, et al. Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial. Ann Intern Med 2005;143:570-80.
7. Bong JJ, Kite P, Wilco MH, McMahon MJ Prevention of catheter related bloodstream infection by silver iontophoretic central venous catheters: a randomised controlled trial. J Clin Pathol 2003;56:731-5.
8. Darouiche RO, Raad II, Heard SO, Thornby JI, Wenker OC, Gabrielli A, et al. A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group. N Engl J Med 1999;340:1-8.
9. Simon A, Ammann RA, Wiszniewsky G, Bode U, Fleischhack G, Besuden MM Taurolidine-citrate lock solution (TauroLock) significantly reduces CVAD-associated grampositive infections in pediatric cancer patients. BMC Infect Dis 2008;8:102.
10. Henrickson KJ, Axtell RA, Hoover SM, Kuhn SM, Pritchett J, Kehl SC, et al. Prevention of central venous catheter-related infections and thrombotic events in immunocompromised children by the use of vancomycin/ciprofloxacin/heparin flush solution: A randomized, multicenter, double-blind trial. J Clin Oncol 2000;18:1269-78.
11. Sanders J, Pithie A, Ganly P, Surgenor L, Wilson R, Merriman E, et al. A prospective double-blind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients. J Antimicrob Chemother 2008;62:809-15.
12. Torres-Viera C, Thauvin-Eliopoulos C, Souli M, DeGirolami P, Farris MG, Wennersten CB, et al. Activities of taurolidine in vitro and in experimental enterococcal endocarditis. Antimicrob Agents Chemother 2000;44:1720-4.
13. Shah CB, Mittelman MW, Costerton JW, Parenteau S, Pelak M, Arsenault R, et al. Antimicrobial activity of a novel catheter lock solution. Antimicrob Agents Chemother 2002;46:1674-9.
14. Watson RW, Redmond HP, Mc CJ, Bouchier-Hayes D Taurolidine, an antilipopolysaccharide agent, has immunoregulatory properties that are mediated by the amino acid taurine. J Leukoc Biol 1995;58:299-306.
15. Allon M Prophylaxis against dialysis catheter-related bacteremia with a novel antimicrobial lock solution. Clin Infect Dis 2003;36:1539-44.
16. Bisseling TM, Willems MC, Versleijen MW, Hendriks JC, Vissers RK, Wanten GJ Taurolidine lock is highly effective in preventing catheter-related bloodstream infections in patients on home parenteral nutrition: A heparin-controlled prospective trial. Clin Nutr 2010;29:464-8.
17. Taylor C, Cahill J, Gerrish M, Little J A new haemodialysis catheter-locking agent reduces infections in haemodialysis patients. J Ren Care 2008;34:116-20.
18. Betjes MG, van AM Prevention of dialysis catheter-related sepsis with a citrate-taurolidine-containing lock solution. Nephrol Dial Transplant 2004;19:1546-51.
19. Solomon LR, Cheesbrough JS, Ebah L, Al-Sayed T, Heap M, Millband N, et al. A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis. Am J Kidney Dis 2010;55:1060-8.
20. Kanaa M, Wright MJ, Sandoe JA Examination of tunnelled haemodialysis catheters using scanning electron microscopy. Clin Microbiol Infect 2009;16:780-6.
21. Bosma JW, Siegert CE, Peerbooms PG, Weijmer MC Reduction of biofilm formation with trisodium citrate in haemodialysis catheters: a randomized controlled trial. Nephrol Dial Transplant 2009;25:1213-7.
22. Maki DG, Weise CE, Sarafin HW A semiquantitative culture method for identifying intravenous-catheter-related infection. N Engl J Med 1977;296:1305-9.
23. Sherertz RJ, Raad II, Belani A, Koo LC, Rand KH, Pickett DL, et al. Three-year experience with sonicated vascular catheter cultures in a clinical microbiology laboratory. J Clin Microbiol 1990;28:76-82.
24. Branger B, Marion K, Bergeron E, Perret C, Zabadani B, Reboul P, et al. Using detachment-promoting agents for the prevention of chronic peritoneal dialysis-associated infections. Artif Organs 2008;32:918-24.
25. Droste JC, Jeraj HA, MacDonald A, Farrington K Stability and in vitro efficacy of antibiotic-heparin lock solutions potentially useful for treatment of central venous catheter-related sepsis. J Antimicrob Chemother 2003;51:849-55.
26. Beenken KE, Dunman PM, McAleese F, Macapagal D, Murphy E, Projan SJ, et al. Global gene expression in Staphylococcus aureus biofilms. J Bacteriol 2004;186:4665-84.
27. Siegman-Igra Y, Anglim AM, Shapiro DE, Adal KA, Strain BA, Farr BM Diagnosis of vascular catheter-related bloodstream infection: a meta-analysis. J Clin Microbiol 1997;35:928-36.
28. Slobbe L, El BA, Boersma E, Rijnders BJ Comparison of the roll plate method to the sonication method to diagnose catheter colonization and bacteremia in patients with long-term tunnelled catheters: a randomized prospective study. J Clin Microbiol 2009;47:885-8.
29. Jones GR, Konsler GK, Dunaway RP, Pusek SN Infection risk factors in febrile, neutropenic children and adolescents. Pediatr Hematol Oncol 1996;13:217-29.