Cutting edge: A novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells

Journal of Immunology

Volumn 189, Issue 6, 2012, Pages 2712-2716

  Lee, Seung Hwan ^a,b   Fragoso, Maria F ^a   Biron, Christine A ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MEMBRANE PROTEIN; NATURAL KILLER CELL ACTIVATING RECEPTOR LY49H; STAT4 PROTEIN; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BODY COMPOSITION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS INFECTION; FLOW CYTOMETRY; INNATE IMMUNITY; LYMPHOCYTE FUNCTION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRUS NEUTRALIZATION;

ADAPTIVE IMMUNITY; ANIMALS; CELL LINE; CELLS, CULTURED; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-12; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; KILLER CELLS, NATURAL; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUROMEGALOVIRUS; PROTEIN BINDING; RECEPTORS, INTERLEUKIN-2;

EID: 84866145249     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201528     Document Type: Article

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