Borna Disease Virus Infection Perturbs Energy Metabolites and Amino Acids in Cultured Human Oligodendroglia Cells

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Huang, Rongzhong ^a,c   Gao, Hongchang ^b   Zhang, Liang ^a,c   Jia, Jianmin ^b   Liu, Xia ^a,c   Zheng, Peng ^a,c   Ma, Lihua ^a,c   Li, Wenjuan ^a,c   Deng, Jing ^a,c   Wang, Xiao ^a,c   Yang, Liu ^a,c   Wang, Mingju ^a,c   Xie, Peng ^a,c  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c CHONGQING KEY LABORATORY OF NEUROBIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ADENINE NUCLEOTIDE; ALPHA GLUCOSE; ASPARTIC ACID; CHOLINE; CREATINE; FORMIC ACID; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HISTIDINE; INOSITOL; ISOLEUCINE; NICOTINAMIDE; PHENYLALANINE; PYRUVIC ACID; SUCCINIC ACID; THREONINE; TYROSINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID ANALYSIS; ARTICLE; BORNA DISEASE; BORNA DISEASE VIRUS; CELL CULTURE; CONTROLLED STUDY; ENERGY METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; METABOLITE; METABOLOMICS; METABONOMICS; NONHUMAN; OLIGODENDROGLIA; PROTON NUCLEAR MAGNETIC RESONANCE; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS STRAIN;

AMINO ACIDS; BORNA DISEASE; CELLS, CULTURED; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; OLIGODENDROGLIA;

BORNA DISEASE VIRUS;

EID: 84866126852     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044665     Document Type: Article

References (46)

1. Ludwig H, Bode L, Gosztonyi G, (1988) Borna disease: a persistent virus infection of the central nervous system. Prog Med Virol 35: 107-151.
2. de la Torre JC,Bode L, Carbone KM, Dietzschold B, Ikuta K, et al. (2000) Family Bornaviridae. In: Virus taxonomy. (MHV van Regenmortel, CM Fauquet, DHL Bishop eds.), London: Academic Press, 531-538.
3. Li Q, Wang Z, Zhu D, Xu M, Chen X, et al. (2009) Detection and analysis of Borna disease virus in Chinese patients with neurological disorders. Eur J Neurol 16: 399-403.
4. Solbrig MV, Koob GF, (2003) Neuropharmacological sequelae of persistent CNS viral infections: lessons from Borna disease virus. Pharmacol Biochem Behav 74: 777-787.
5. Pletnikov MV, Rubin SA, Schwartz GJ, Carbone KM, Moran TH, (2000) Effects of neonatal rat Borna disease virus (BDV) infection on the postnatal development of the brain monoaminergic systems. Brain Res Dev Brain Res 119: 179-185.
6. Gosztonyi G, Ludwig H, (2001) Interactions of viral proteins with neurotransmitter receptors may protect or destroy neurons. Curr Top Microbiol Immunol 253: 121-144.
7. Dittrich W, Bode L, Ludwig H, Kao M, Schneider K, (1989) Learning deficiencies in Borna disease virus-infected but clinically healthy rats. Biol Psychiatry 26: 818-828.
8. Beckonert O, Keun HC, Ebbels TM, Bundy J, Holmes E, et al. (2007) Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat Protoc 2: 2692-2703.
9. Nicholson JK, Lindon JC, Holmes E, (1999) 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29: 1181-1189.
10. Sripadi P, Shrestha B, Easley RL, Carpio L, Kehn-Hall K, et al. (2010) Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry. PLoS One 5: e12590.
11. Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD, (2006) Dynamics of the cellular metabolome during human cytomegalovirus infection. PLoS Pathog 2: e132.
12. Akhtar SN, Singh RK, Jadegoud Y, Dhole TN, Ayyagari A, et al. (2007) In vitro (1)H NMR studies of RD human cell infection with echovirus 11. NMR Biomed 20: 422-428.
13. Bode L, Durrwald R, Rantam FA, Ferszt R, Ludwig H, (1996) First isolates of infectious human Borna disease virus from patients with mood disorders. Mol Psychiatry 1: 200-212.
14. Muller CF, Fatzer RS, Beck K, Vandevelde M, Zurbriggen A, (1995) Studies on canine distemper virus persistence in the central nervous system. Acta Neuropathol 89: 438-445.
15. Baczko K, Liebert UG, Cattaneo R, Billeter MA, Roos RP, et al. (1988) Restriction of measles virus gene expression in measles inclusion body encephalitis. J Infect Dis 158: 144-150.
16. Qian J, Zhai A, Kao W, Li Y, Song W, et al. (2010) Modulation of miR-122 on persistently Borna disease virus infected human oligodendroglial cells. Antiviral Res 87: 249-256.
17. Ibrahim MS, Watanabe M, Palacios JA, Kamitani W, Komoto S, et al. (2002) Varied persistent life cycles of Borna disease virus in a human oligodendroglioma cell line. J Virol 76: 3873-3880.
18. Horie M, Honda T, Suzuki Y, Kobayashi Y, Daito T, et al. (2010) Endogenous non-retroviral RNA virus elements in mammalian genomes. Nature 463: 84-87.
19. Feschotte C, (2010) Virology: Bornavirus enters the genome. Nature 463: 39-40.
20. Bode L, Ludwig H, (2003) Borna disease virus infection, a human mental-health risk. Clin Microbiol Rev 16: 534-545.
21. Hornig M, Briese T, Licinio J, Khabbaz RF, Altshuler LL, et al. (2012) Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder. Mol Psychiatry 17: 486-493.
22. Hornig M, Solbrig M, Horscroft N, Weissenbock H, Lipkin WI, (2001) Borna disease virus infection of adult and neonatal rats: models for neuropsychiatric disease. Curr Top Microbiol Immunol 253: 157-177.
23. Utrilla J, Gosset G, Martinez A, (2009) ATP limitation in a pyruvate formate lyase mutant of Escherichia coli MG1655 increases glycolytic flux to D-lactate. J Ind Microbiol Biotechnol 36: 1057-1062.
24. Feron O, (2009) Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Radiother Oncol 92: 329-333.
25. Schurr A, Payne RS, (2007) Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. Neuroscience 147: 613-619.
26. Fernie AR, Carrari F, Sweetlove LJ, (2004) Respiratory metabolism: glycolysis, the TCA cycle and mitochondrial electron transport. Curr Opin Plant Biol 7: 254-261.
27. Tilton WM, Seaman C, Carriero D, Piomelli S, (1991) Regulation of glycolysis in the erythrocyte: role of the lactate/pyruvate and NAD/NADH ratios. J Lab Clin Med 118: 146-152.
28. Mason GF, Gruetter R, Rothman DL, Behar KL, Shulman RG, et al. (1995) Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR. J Cereb Blood Flow Metab 15: 12-25.
29. Mason GF, Rothman DL, Behar KL, Shulman RG, (1992) NMR determination of the TCA cycle rate and alpha-ketoglutarate/glutamate exchange rate in rat brain. J Cereb Blood Flow Metab 12: 434-447.
30. Rich PR, (2003) The molecular machinery of Keilin's respiratory chain. Biochem Soc Trans 31: 1095-1105.
31. Ritter JB, Wahl AS, Freund S, Genzel Y, Reichl U, (2010) Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling. BMC Syst Biol 4: 61.
32. Kohno T, Goto T, Takasaki T, Morita C, Nakaya T, et al. (1999) Fine structure and morphogenesis of Borna disease virus. J Virol 73: 760-766.
33. Pauli G, Ludwig H, (1985) Increase of virus yields and releases of Borna disease virus from persistently infected cells. Virus Res 2: 29-33.
34. Liu ST, Sharon-Friling R, Ivanova P, Milne SB, Myers DS, et al. (2011) Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress. Proc Natl Acad Sci U S A 108: 12869-12874.
35. Clemente R, de Parseval A, Perez M, de la Torre JC, (2009) Borna disease virus requires cholesterol in both cellular membrane and viral envelope for efficient cell entry. J Virol 83: 2655-2662.
36. Lou HC, (1994) Dopamine precursors and brain function in phenylalanine hydroxylase deficiency. Acta Paediatr Suppl 407: 86-88.
37. Zhang CX, Ofiyai H, He M, Bu X, Wen Y, et al. (2005) Neuronal activity regulates viral replication of herpes simplex virus type 1 in the nervous system. J Neurovirol 11: 256-264.
38. Aguilar E, Tena-Sempere M, Pinilla L, (2005) Role of excitatory amino acids in the control of growth hormone secretion. Endocrine 28: 295-302.
39. Legendre P, (2001) The glycinergic inhibitory synapse. Cell Mol Life Sci 58: 760-793.
40. Li YH, Han TZ, (2008) Glycine modulates synaptic NR2A- and NR2B-containing NMDA receptor-mediated responses in the rat visual cortex. Brain Res 1190: 49-55.
41. Fleck MW, Henze DA, Barrionuevo G, Palmer AM, (1993) Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus. J Neurosci 13: 3944-3955.
42. Ovanesov MV, Vogel MW, Moran TH, Pletnikov MV, (2007) Neonatal Borna disease virus infection in rats is associated with increased extracellular levels of glutamate and neurodegeneration in the striatum. J Neurovirol 13: 185-194.
43. Ludwig H, Furuya K, Bode L, Klein N, Durrwald R, et al. (1993) Biology and neurobiology of Borna disease viruses (BDV), defined by antibodies, neutralizability and their pathogenic potential. Arch Virol Suppl 7: 111-133.
44. de la Torre JC, Bode L, Durrwald R, Cubitt B, Ludwig H, (1996) Sequence characterization of human Borna disease virus. Virus Res 44: 33-44.
45. Y Benjamini Y, Yekutieli D, (2001) The control of the false discovery rate in multiple testing under dependency. Ann.Statist 29: 1165-1188.
46. Mashego MR, Rumbold K, De Mey M, Vandamme E, Soetaert W, et al. (2007) Microbial metabolomics: past, present and future methodologies. Biotechnol Lett 29: 1-16.