Transjugular intrahepatic portosystemic shunt may be superior to conservative therapy for variceal rebleeding in cirrhotic patients with non-tumoral portal vein thrombosis: A hypothesis

Medical Science Monitor

Volumn 18, Issue 8, 2012, Pages

  Qi, Xingshun ^a   Han, Guohong ^a   He, Chuangye ^a   Yin, Zhanxin ^a   Zhang, Hongbo ^a   Wang, Jianhong ^a   Xia, Jielai ^b   Cai, Hongwei ^b   Yang, Zhiping ^a   Bai, Ming ^a   Wu, Kaichun ^a   Fan, Daiming ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Anticoagulation; Endoscopic therapy; Liver cirrhosis; Portal vein thrombosis; Transjugular intrahepatic portosystemic shunt; Variceal bleeding

Indexed keywords

ANTICOAGULANT AGENT;

ANTICOAGULANT THERAPY; ARTICLE; BLEEDING; CONSERVATIVE TREATMENT; ENDOSCOPIC THERAPY; ENDOVASCULAR SURGERY; HUMAN; HYPOTHESIS; LIVER CIRRHOSIS; PORTAL VEIN; PORTAL VEIN THROMBOSIS; PROGNOSIS; RECANALIZATION; RISK; SURVIVAL; TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT; VARICEAL REBLEEDING; VASCULAR PATENCY;

EID: 84866110738     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.883252     Document Type: Article

References (43)

1. Valla DC, Condat B: Portal vein thrombosis in adults: pathophysiology, pathogenesis and management. J Hepatol, 2000; 32: 865-71
2. Primignani M: Portal vein thrombosis, revisited. Dig Liver Dis, 2010; 42: 163-70
3. Fimognari FL, Violi F: Portal vein thrombosis in liver cirrhosis. Intern Emerg Med, 2008; 3: 213-18
4. Tsochatzis EA, Senzolo M, Germani G et al: Systematic review: portal vein thrombosis in cirrhosis. Aliment Pharmacol Ther, 2010; 31: 366-74
5. Amitrano L, Brancaccio V, Guardascione MA et al: Portal vein thrombosis after variceal endoscopic sclerotherapy in cirrhotic patients: role of genetic thrombophilia. Endoscopy, 2002; 34: 535-38
6. Francoz C, Belghiti J, Vilgrain V et al: Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation. Gut, 2005; 54: 691-97
7. Zocco MA, Di Stasio E, De Cristofaro R et al: Thrombotic risk factors in patients with liver cirrhosis: correlation with MELD scoring system and portal vein thrombosis development. J Hepatol, 2009; 51: 682-89
8. Amitrano L, Brancaccio V, Guardascione MA et al: Inherited coagulation disorders in cirrhotic patients with portal vein thrombosis. Hepatology, 2000; 31: 345-48
9. Tripodi A, Primignani M, Chantarangkul V et al: An imbalance of pro-vs anti-coagulation factors in plasma from patients with cirrhosis. Gastroenterology, 2009;137: 2105-11
10. Martinelli I, Primignani M, Aghemo A et al: High levels of factor VIII and risk of extra-hepatic portal vein obstruction. J Hepatol, 2009; 50: 916-22
11. Garcia-Pagan JC, Valla DC: Portal vein thrombosis: A predictable milestone in cirrhosis? J Hepatol, 2009; 51: 632-34
12. Qi X, Bai M, Yang Z et al: Occlusive portal vein thrombosis as a new marker of decompensated cirrhosis. Med Hypotheses, 2011; 76: 522-26
13. D'Amico G, de Franchis R: Upper digestive bleeding in cirrhosis. Posttherapeutic outcome and prognostic indicators. Hepatology, 2003; 38: 599-612
14. Englesbe MJ, Kubus J, Muhammad W et al: Portal vein thrombosis and survival in patients with cirrhosis. Liver Transpl, 2010; 16: 83-90
15. DeLeve LD, Valla DC, Garcia-Tsao G: Vascular disorders of the liver. Hepatology, 2009; 49: 1729-64
16. de Franchis R: Revising consensus in portal hypertension: Report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol, 2010; 53: 762-68
17. Amitrano L, Guardascione MA, Menchise A et al: Safety and Efficacy of Anticoagulation Therapy With Low Molecular Weight Heparin for Portal Vein Thrombosis in Patients With Liver Cirrhosis. J Clin Gastroenterol, 2010; 44: 448-51
18. Senzolo M, Ferronato C, Burra P, Sartori MT: Anticoagulation for portal vein thrombosis in cirrhotic patients should be always considered. Intern Emerg Med, 2009; 4: 161-62; author reply 163-64
19. Delgado MG, Seijo S, Yepes I et al: Efficacy and safety of anticoagulation on patients with cirrhosis and portal vein thrombosis. Clin Gastroenterol Hepatol 2012 [Epub ahead of print]
20. Qi X, Han G, Wu K, Fan D: Anticoagulation for portal vein thrombosis in cirrhosis. Am J Med, 2010; 123: e19-20; author reply e21
21. Valla DC: Anticoagulation in cirrhosis. International Liver Congress 2011. Berlin, Germany
22. Qi X, Han G, Bai M, Fan D: Stage of portal vein thrombosis. J Hepatol, 2011; 54: 1080-82
23. Qi X, Han G, Wang J et al: Degree of portal vein thrombosis. Hepatology, 2010; 51: 1089-90
24. Han G, Qi X, He C et al: Transjugular intrahepatic portosystemic shunt for portal vein thrombosis with symptomatic portal hypertension in liver cirrhosis. J Hepatol, 2011; 54: 78-88
25. O'Leary JG, Lepe R, Davis GL: Indications for liver transplantation. Gastroenterology, 2008; 134: 1764-76
26. Thatipelli MR, McBane RD, Hodge DO, Wysokinski WE: Survival and recurrence in patients with splanchnic vein thromboses. Clin Gastroenterol Hepatol, 2010; 8: 200-5
27. Qi X, Han G, Fan D: The preferable treatment for cirrhotic portal vein thrombosis: anticoagulation or transjugular intrahepatic portosystemic shunt? Hepatology, 2010; 51: 713-14
28. Blum U, Haag K, Rossle M et al: Noncavernomatous portal vein thrombosis in hepatic cirrhosis: treatment with transjugular intrahepatic portosystemic shunt and local thrombolysis. Radiology, 1995; 195: 153-57
29. Van Ha TG, Hodge J, Funaki B et al: Transjugular intrahepatic portosystemic shunt placement in patients with cirrhosis and concomitant portal vein thrombosis. Cardiovasc Intervent Radiol, 2006; 29: 785-90
30. Luca A, Miraglia R, Caruso S et al: Short-and long-term effects of the transjugular intrahepatic portosystemic shunt on portal vein thrombosis in patients with cirrhosis. Gut, 2011; 60: 846-52
31. Perarnau JM, Baju A, D'Alteroche L et al: Feasibility and long-term evolution of TIPS in cirrhotic patients with portal thrombosis. Eur J Gastroenterol Hepatol, 2010; 22: 1093-98
32. Qi X, Han G: Transjugular intrahepatic portosystemic shunt in the treatment of portal vein thrombosis: a critical review of literature. Hepatol Int, 2012; 6: 576-90
33. Garcia-Tsao G, Sanyal AJ et al: Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology, 2007; 46: 922-38
34. Luca A, D'Amico G, La Galla R et al: TIPS for prevention of recurrent bleeding in patients with cirrhosis: meta-analysis of randomized clinical trials. Radiology, 1999; 212: 411-21
35. Zheng M, Chen Y, Bai J et al: Transjugular Intrahepatic Portosystemic Shunt Versus Endoscopic Therapy in the Secondary Prophylaxis of Variceal Rebleeding in Cirrhotic Patients: Meta-analysis Update. J Clin Gastroenterol, 2008; 42: 507-16
36. Garcia-Tsao G, Lim JK: Management and treatment of patients with cirrhosis and portal hypertension: recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program. Am J Gastroenterol, 2009; 104: 1802-29
37. Korula J, Ralls P: The effects of chronic endoscopic variceal sclerotherapy on portal pressure in cirrhotics. Gastroenterology, 1991; 101: 800-5
38. Lo GH, Liang HL, Lai KH et al: The impact of endoscopic variceal ligation on the pressure of the portal venous system. J Hepatol, 1996; 24: 74-80
39. D'Amico G, Garcia-Tsao G, Pagliaro L: Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies. J Hepatol, 2006; 44: 217-31
40. Bureau C, Pagan JC, Layrargues GP et al: Patency of stents covered with polytetrafluoroethylene in patients treated by transjugular intrahepatic portosystemic shunts: long-term results of a randomized multicentre study. Liver Int, 2007; 27: 742-47
41. Yang Z, Han G, Wu Q et al: Patency and clinical outcomes of transjugular intrahepatic portosystemic shunt with polytetrafluoroethylene-covered stents versus bare stents: a meta-analysis. J Gastroenterol Hepatol, 2010; 25: 1718-25
42. Garcia-Pagan JC, Caca K, Bureau C et al: Early use of TIPS in patients with cirrhosis and variceal bleeding. N Engl J Med, 2010; 362: 2370-79
43. Afdhal NH, Curry MP: Early TIPS to improve survival in acute variceal bleeding. N Engl J Med, 2010; 362: 2421-22