Immunomodulatory effects of poly (Ethylene glycol) microspheres adsorbed with cortisol on activity of colostrum phagocytes

International Journal of Pharmacology

Volumn 8, Issue 6, 2012, Pages 510-518

  Fagundes, Danny Laura Gomes ^a   França, Eduardo Luzía ^a   Hara, Cristiane de Castro Pernet ^a   Honorio França, Adenilda Cristina ^a  

^a FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

Author keywords

Colostrum; Cortisol; PEG microsphere; Phagocytes

Indexed keywords

HYDROCORTISONE; MACROGOL MICROSPHERE; POLY(METHYL METHACRYLATE); POLYMER; SUPEROXIDE; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; BACTERICIDAL ACTIVITY; CALCIUM TRANSPORT; CELL FUNCTION; CELL VIABILITY; COLOSTRUM; CONTROLLED STUDY; DRUG ACTIVITY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOMODULATORY EFFECT; IMMUNOSTIMULATORY EFFECT; INFECTION; MICROBICIDAL ACTIVITY; MONONUCLEAR PHAGOCYTE; PHAGOCYTOSIS;

EID: 84866109476     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2012.510.518     Document Type: Article

References (38)

1. Ackermann, K., K.N. Ballantyne and M. Kayser, 2010. Estimating trace deposition time with circadian biomarkers: A prospective and versatile too for crime scene reconstruction. Int. J. Legal Med., 124: 387-395.
2. Allen, T.M., 2005. Ligand-targeted therapeutics in anticancer therapy. Nature Rev. Cancer, 2: 750-763.
3. Bernt, K.M. and W.A. Walker, 2009. Human milk as cariier of biochemical messages. Acta Pediat., 430: 27-41.
4. Carneiro-Sampaio, M.M.S., M.L. da Silva, S.B. Carbonare, P. Palmeira, M.T. Delneri, A.C. Honorio and L.R. Trabulsi, 1996. Breast-feeding protection against enteropathogenic Escherichia coli. Rev. Microbiol., 27: 120-125.
5. Carrichon, L., A. Picciocchi, F. Debeurme, A. Defendi and S. Beaumel et al., 2011. Characterization of superoxide overproduction by the D-LoopNox4-Nox2 cytochrome b558 in phagocytes-differential sensitivity to calcium and phosphorylation events. Bioch. Biophys. Acta, 1808: 78-90.
6. Caspari, G.R., 1993. The influence of colostral leukocytes on the couse of an experimental Escherichia coli infection and serum antibodies in neonatal calves. Vet. Immunol. Immunopathol., 35: 275-288.
7. Davis, F.F., 2002. The origin of pegnology. Adv. Drug Deliv. Rev., 54: 457-458.
8. Ferrari, C.K.B., E.L. Franca and A.C. Honorio-Franca, 2009. Nitric oxide, health and disease. J. Applied Biomed., 7: 163-173.
9. Franca, E., A. Pereira-Junior, S.L. Oliveira and A.C. Honorio-Franca, 2009. Chronoimmunomodulation of melatonin on bactericidal activity of human blood phagocytes. Int. J. Microbiol., 6: 1-13.
10. Franca, E.L., G. Morceli, D.L.G. Fagundes, M.V.C. Rugde, I.M.P. Calderon and A.C. Honorio-Franca, 2011. Secretory IgA-Fca Receptor interaction modulating phagocytosis and microbicidal activity by phagocytes in human colostrum of diabetics. APMIS., 119: 710-719.
11. Franca, E.L., J.C. Maynie, V.S.C. Correa, U.C.R. Pereira, C. Batalini, C.K.B. Ferrari and A.C. Honorio-Franca, 2010. Immunomodulatory effects of herbal plants plus melatonin on human blood phagocytes. Int. J. Phytomed., 2: 354-362.
12. Franca, E.L., N.D. Feliciano, K.A. Silva, C.K.B. Ferrari and A.C. Honorio-Franca, 2009. Modulatory role of melatonin on superoxide release by spleen macrophages isolated from alloxan-induced diabetic rats. Bratisl. Med. J., 110: 517-522.
13. Franca, E.L., R.V. Bitencourt, M. Fujimori, T.C. de Morais, I.M.P. Calderon and A.C. Honorio-Franca, 2011. Human colostral phagocytes eliminate enterotoxigenic Eschechia coli opsonized by colostrum supernatant. J. Microbiol. Immunol. Infect., 44: 1-7.
14. Franca-Botelho, A.C., J.L. Franca, F.M. Oliveira, E.L. Franca, A.C. Honorio-Franca, M.V. Caliari and M.A. Gomes, 2011. Melatonin reduces the severity of experimental amoebiasis. Parasites Vectors, vol 4,
15. Freiberg, S. and X.X. Zhu, 2004. Polymer microspheres for controlled drug release. Int. J. Pharm., 282: 1-18.
16. Gardner, J.P. and L. Zhang, 1999. Glucocorticoid modulation of Ca2+ homeostasis in humn B lymphoblasts. J. Physiol., 514: 385-396.
17. Goldblum, R.M. and A.S. Goldman, 1994. Immunological Components of Milk: Formation and Function. In: Handbook Mucosal Immunology, Ogra, P.L., M.E. Lamm, J.R. McGhee, J. Mestecky, W. Strober and J. Bienenstock (Eds.). Academic Press, New York, pp: 643-652.
18. Henning, T., 2002. Polyethyleneglycols (PEGs) and the pharmaceutical industry. Fine Special Perform. Chem., 1: 57-59.
19. Honorio-Franca, A.C., M.P. Carvalho, L. Isaac, L.R. Trabulsi and M.M.S. Carneiro-Sampaio, 1997. Colostral mononuclear phagocytes are able to kill enteropathogenic Escherichia coli opsonized with colostral IgA. Scand. J. Immunol., 46: 59-66.
20. Hugaes, A., J.H. Brock, D.M.V. Parrott and F. Cockburn, 1988. The interaction of infant formula with macrophages: Effect on phagocytic activity, relationship to expression of class II MHC antigen and survival of orally administered macrophages in the neonatal gut. Immunology, 64: 213-218.
21. Jevsevar, S., J.M. Kunstel and V.G. Porekar, 2010. PEGylation of therapeutic proteins. Biotechnol. J., 5: 113-128.
22. Kiick, K.L., 2007. Polymer therapeutics. Science, 317: 1182-1183.
23. Kohut, M.L., A.E. Martin, D.S. Senchina and W. Lee, 2005. Glucocorticoids produced during exercise may be necessary for optimal virus-induced IL-2 and cell proliferation whereas both catecholamines and glucocorticoids may be required for adequate immune defense to viral infection. Brain Behav. Immunol., 19: 423-435.
24. Lim, H.Y., N. Muller, M.J. Herold, J. van den Brandt and T.H.M. Reichardt, 2007. Glucocorticoids exert opposing effects on macrophage function dependent on their concentration. Immunology, 122: 47-53.
25. Long, F., Y.X. Wang, L. Liu, J. Zhou, R.Y. Cui and C.L. Jiang, 2005. Rapid nongenomic inhibitory effects of glucocorticoids on phagocytosis and superoxide anion production by macrophages. Steroids, 70: 55-61.
26. Novelli, E.L.B., N.L. Rodrigues, E.L. Franca, L.M.M. Gebra and B.O. Ribas, 1993. High dietary carbohydrate and pancreatic lesion. Braz. J. Med. Biol. Res., 26: 31-36.
27. Park, J., M. Ye and K. Park, 2005. Biodegradable polymers for microencapsulation of drugs. Molecules, 10: 146-161.
28. Pick, E. and D. Mizel, 1981. Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader. J. Immunol. Methods, 46: 211-226.
29. Rady, M.Y., D.J. Johnson, B. Patel, J. Larson and R. Helmers, 2006. Corticosteroids influence the mortality and morbidity of acute critical illness. Crit. Care, vol 10,
30. Reul, J.M.H.M. and Y. Chandramohan, 2007. Epigenetic mechanisms in stress related. Psychoneuroendocrinology, 32: S21-S25.
31. Sauter, S.N., B. Roffler, C. Philipona, C. Morel and V. Rome et al., 2004. Intestinal development in neonatal calves: Effects of glucocorticoids and dependence on colostrum feeding. Biol. Neonate, 85: 94-104.
32. Scherer, E.F., A.C. Honorio-Franca, C.C.P. Hara, A.P.B. Reinaque, M.A. Cortes and E.L. Franca, 2011. Immunomodulatory effects of poly (ethylene glycol) microspheres adsorbed with nanofractions of Momordica charantia L. on diabetic human blood phagocytes. Sci. Adv. Mater., 3: 687-694.
33. Scott, E.A., M.D. Nichols, R. Kuntz-Willits and D.L. Elbert, 2010. Modular scaffolds assembled around living cells using poly (ethylene glycol) microspheres with macroporation via a non-cytotoxic porogen. Acta Biomater., 6: 29-38.
34. Stadler, B., A.D. Price and A.N. Zelikin, 2011. A critical look at multilayered polymer capsules in biomedicine: Drug carriers, Arti? cial organelles and cell mimics. Adv. Funct. Mater., 21: 14-28.
35. Wang, X.Q., E. Wenk, Z.H. Zhang, L. Mennel, G. Vunjak-Novakovic and D.L. Kaplan, 2009. Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. J. Control Release, 134: 81-90.
36. Watts, N.B. and G.T. Tindall, 1988. Rapis assessment of corticotrophin reserve after pituitary surgery. JAMA., 259: 708-712.
37. Zanettil, B.G., V. Soldi and E. Lemos-Senna, 2002. Effect of polyethylene glycols addition in microsphere formulations of cellullose acetate butyrate on efficacy carbamazepine and particles morphology encapsulation. Braz. J. Pharma. Sci., 38: 229-236.
38. Zar, J.H., 1984. Bioestatical Analysis. Prentice-Hall, Englewood cliffs, NJ, USA.