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Volumn 55, Issue 10, 2012, Pages 2551-2554

Revisiting the connection between intramyocellular lipids and insulin resistance: A long and winding road

Author keywords

Diabetes; Fatty acids; Insulin resistance; Intramyocellular triacylglycerol; Lipid droplet; Muscle; NMR; Obesity

Indexed keywords

FAT DROPLET; GLUCOSE; INTRAMYOCELLULAR LIPID; LIPID; UNCLASSIFIED DRUG; INSULIN;

EID: 84866105830     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2597-y     Document Type: Article
Times cited : (36)

References (13)
  • 1
    • 0018602501 scopus 로고
    • Changes in lipoprotein-lipase activity and lipid stores in human skeletal muscle with prolonged heavy exercise
    • Lithell H, Orlander J, Schele R, Sjodin B, Karlsson J (1979) Changes in lipoprotein-lipase activity and lipid stores in human skeletal muscle with prolonged heavy exercise. Acta Physiol Scand 107:257-261 (Pubitemid 10172575)
    • (1979) Acta Physiologica Scandinavica , vol.107 , Issue.3 , pp. 257-261
    • Lithell, H.1    Orlander, J.2    Schele, R.3
  • 3
    • 76049118432 scopus 로고    scopus 로고
    • Intramuscular triacylglycerol and insulin resistance: Guilty as charged or wrongly accused?
    • 19958841 10.1016/j.bbalip.2009.11.007 1:CAS:528:DC%2BC3cXitVejtLk%3D
    • Muoio DM (2010) Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused? Biochim Biophys Acta 1801:281-288
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 281-288
    • Muoio, D.M.1
  • 4
    • 39749147110 scopus 로고    scopus 로고
    • Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
    • DOI 10.1038/nrm2327, PII NRM2327
    • Muoio DM, Newgard CB (2008) Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol 9:193-205 (Pubitemid 351301824)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.3 , pp. 193-205
    • Muoio, D.M.1    Newgard, C.B.2
  • 5
    • 0036092239 scopus 로고    scopus 로고
    • Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
    • 11756317 10.2337/diabetes.51.1.7 1:CAS:528:DC%2BD38Xlt1ejsQ%3D%3D
    • McGarry JD (2002) Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 51:7-18
    • (2002) Diabetes , vol.51 , pp. 7-18
    • McGarry, J.D.1
  • 6
    • 0032452225 scopus 로고    scopus 로고
    • Regulatory interactions between lipids and carbohydrates: The glucose fatty acid cycle after 35 years
    • DOI 10.1002/(SICI)1099-0895(199812)14:4<263::AID-DMR233>3.0.CO;2-C
    • Randle PJ (1998) Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years. Diabetes Metab Rev 14:263-283 (Review) (Pubitemid 29110250)
    • (1998) Diabetes/Metabolism Reviews , vol.14 , Issue.4 , pp. 263-283
    • Randle, P.J.1
  • 8
    • 0345374579 scopus 로고    scopus 로고
    • Minireview: Weapons of Lean Body Mass Destruction: The Role of Ectopic Lipids in the Metabolic Syndrome
    • DOI 10.1210/en.2003-0870
    • Unger RH (2003) Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome. Endocrinology 144:5159-5165 (Pubitemid 37476041)
    • (2003) Endocrinology , vol.144 , Issue.12 , pp. 5159-5165
    • Unger, R.H.1
  • 9
    • 0035217707 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurance-trained athletes
    • DOI 10.1210/jc.86.12.5755
    • Goodpaster BH, He J, Watkins S, Kelley DE (2001) Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J Clin Endocrinol Metab 86:5755-5761 (Pubitemid 33152620)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.12 , pp. 5755-5761
    • Goodpaster, B.H.1    He, J.2    Watkins, S.3    Kelley, D.E.4
  • 10
    • 34249915334 scopus 로고    scopus 로고
    • Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance
    • DOI 10.1172/JCI30566
    • Schenk S, Horowitz JF (2007) Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance. J Clin Invest 117:1690-1698 (Pubitemid 46871353)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.6 , pp. 1690-1698
    • Schenk, S.1    Horowitz, J.F.2
  • 11
    • 34249894505 scopus 로고    scopus 로고
    • Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
    • DOI 10.1172/JCI30565
    • Liu L, Zhang Y, Chen N, Shi X, Tsang B, Yu YH (2007) Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance. J Clin Invest 117:1679-1689 (Pubitemid 46871352)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.6 , pp. 1679-1689
    • Liu, L.1    Zhang, Y.2    Chen, N.3    Shi, X.4    Tsang, B.5    Yu, Y.-H.6
  • 12
    • 79960636348 scopus 로고    scopus 로고
    • Not just fat: The structure and function of the lipid droplet
    • pii:a004838
    • Fujimoto T, Parton RG (2011) Not just fat: the structure and function of the lipid droplet. Cold Spring Harb Perspect Biol 3:pii:a004838
    • (2011) Cold Spring Harb Perspect Biol , vol.3
    • Fujimoto, T.1    Parton, R.G.2
  • 13
    • 80052454265 scopus 로고    scopus 로고
    • ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1
    • 21857651 10.1038/nm.2439 1:CAS:528:DC%2BC3MXhtVGksr%2FP
    • Haemmerle G, Moustafa T, Woelkart G et al (2011) ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat Med 17:1076-1085
    • (2011) Nat Med , vol.17 , pp. 1076-1085
    • Haemmerle, G.1    Moustafa, T.2    Woelkart, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.