Necroptosis contributes to the cyclosporin A-induced cytotoxicity in NRK-52E cells

Pharmazie

Volumn 67, Issue 8, 2012, Pages 725-732

  Ouyang, Zizhang ^a   Zhu, Shaohua ^a   Jin, Jing ^a   Li, Jia ^a   Qiu, Yuwen ^a   Huang, Min ^a,b   Huang, Zhiying ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Qingyuan People's Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; REACTIVE OXYGEN METABOLITE; RECEPTOR; RECEPTOR INTERACTION PROTEIN 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL DEATH; CELL LINE; DRUG CYTOTOXICITY; FLOW CYTOMETRY; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; INCUBATION TIME; KIDNEY TUBULE CELL; NECROPTOSIS; NRK 52E CELL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; BENZIMIDAZOLES; BLOTTING, WESTERN; CELL DEATH; CELL LINE; CYCLOSPORINE; FLOW CYTOMETRY; IMIDAZOLES; IMMUNOSUPPRESSIVE AGENTS; INDOLES; KIDNEY TUBULAR NECROSIS, ACUTE; L-LACTATE DEHYDROGENASE; NECROSIS; RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

EID: 84866086929     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2012.1837     Document Type: Article

References (29)

1. Bakker RC, van Kooten C, van de Lagemaat-Paape ME, Daha MR, Paul LC (2002) Renal tubular epithelial cell death and cyclosporin A. Nephrol Dial Transplant 17: 1181-1188.
2. Borel JF, Baumann G, Chapman I, Donatsch P, Fahr A, Mueller EA, Vigouret JM (1996) In vivo pharmacological effects of ciclosporin and some analogues. Adv Pharmacol 35: 115-246.
3. Burdmann EA, Andoh TF, Yu L, Bennett WM (2003) Cyclosporine nephrotoxicity. Semin Nephrol 23: 465-476.
4. Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, Chan FK (2009) Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137: 1112-1123.
5. Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J (2005) Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1: 112-119.
6. Han W, Xie J, Li L, Liu Z, Hu X (2009) Necrostatin-1 reverts shikonininduced necroptosis to apoptosis. Apoptosis 14: 674-686.
7. He S, Wang L, Miao L, Wang T, Du F, Zhao L, Wang X (2009) Receptor interacting protein kinase-3 determines cellular necrotic response to TNFalpha. Cell 137: 1100-1111.
8. Healy E, Dempsey M, Lally C, Ryan MP (1998) Apoptosis and necrosis: mechanisms of cell death induced by cyclosporine A in a renal proximal tubular cell line. Kidney Int 54: 1955-1966.
9. Justo P, Lorz C, Sanz A, Egido J, Ortiz A (2003) Intracellular mechanisms of cyclosporin A-induced tubular cell apoptosis. J Am Soc Nephrol 14: 3072-3080.
10. Kahan BD (1992) Immunosuppressive therapy. Curr Opin Immunol 4: 553-560.
11. Lee SY, Jo SK, Cho WY, Kim HK, Won NH (2004) The effect of alpha-melanocyte- stimulating hormone on renal tubular cell apoptosis and tubulointerstitial fibrosis in cyclosporine A nephrotoxicity. Transplantation 78: 1756-1764.
12. Li C, Lim SW, Sun BK Choi BS, GLowacka S, Cox A, Kelly D, Kim YS, Kim J, Bang BK, Yang CW (2004) Expression of apoptosis-related factors in chronic cyclosporine nephrotoxicity after cyclosporine withdrawal. Acta Pharmacol Sin 25: 401-411.
13. Majno G, Joris I (1995) Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 146: 3-15.
14. Mihatsch MJ, Ryffel B, Hermle M, Brunner FP, Thiel G. (1986) Morphology of cyclosporine nephrotoxicity in the rat. Clin Nephrol 25 Suppl 1: S2-8.
15. Myers BD, Sibley R, Newton L, Tomlanovich SJ, Boshkos C, Stinson E, Luetscher JA, Whitney DJ, Krasny D, Coplon NS et al. (1988) The longterm course of cyclosporine-associated chronic nephropathy. Kidney Int 33: 590-600.
16. Nakamura T, Nozu K, Iijima K, Yoshikawa N, Moriya Y, Yamamori M, Kako A, Matsuo M, Sakurai A, Okamura N, Ishikawa T, Okumura K, Sakaeda T (2007) Association of cumulative cyclosporine dose with its irreversible nephrotoxicity in Japanese patients with pediatric-onset autoimmune diseases. Biol Pharm Bull 30: 2371-2375.
17. Nickeleit V, Zeiler M, Gudat F, Thiel G, Mihatsch MJ (1998) Histological characteristics of interstitial renal allograft rejection. Kidney Blood Press Res 21: 230-232.
18. Niu Q, Zhang QL, Zheng JP, Liu CY, Wang L (2009) [Role of necroptosis in aluminum induced SH-SY5Y cell death]. Zhonghua Yu Fang Yi Xue Za Zhi 43: 132-136.
19. Racusen LC (1993) Tubular injury in human kidneys: pathologic findings and pathogenic mechanisms. Clin Investig 71: 858-860.
20. Shihab FS, Bennett WM, Yi H, Andoh TF (2005) Effect of pirfenidone on apoptosis-regulatory genes in chronic cyclosporine nephrotoxicity. Transplantation 79: 419-426.
21. Song KJ, Jang YS, Lee YA, Kim KA, Lee SK, Shin MH (2011) ROS-dependent necroptosis in Jurkat T cells induced by pathogenic free-living Naegleria fowleri. Parasite Immunol 33: 390-400.
22. Teng X, Degterev A, Jagtap P, Xing X, Choi S, Denu R, Yuan J, Cuny GD (2005) Structure-activity relationship study of novel necroptosis inhibitors. Bioorg Med Chem Lett 15: 5039-5044.
23. Thapa RJ, Basagoudanavar S, Nogusa S, Irrinki K, Mallilankaraman K, Slifker MJ, Beg AA, Madesh M, Balachandran S (2011) NF-{kappa}B protects cells from interferon-{gamma}-induced RIP1- dependent necroptosis. Mol Cell Biol 31: 2934-2946.
24. Vandenabeele P, Galluzzi L,Vanden Berghe T, Kroemer G (2010) Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 11: 700-714.
25. Wroblewski F, Ladue JS (1955) Lactic dehydrogenase activity in blood. Proc Soc Exp Biol Med 90: 210-213.
26. Xu X, Chua CC, Kong J, Kostrzewa RM, Kumaraguru U, Hamdy RC, Chua BH (2007) Necrostatin-1 protects against glutamate-induced glutathione depletion and caspase-independent cell death in HT-22 cells. J Neurochem 103: 2004-2014.
27. Yang CW, Faulkner GR, Wahba IM, Christianson TA, Bagby GC, Jin DC, Abboud HE, Andoh TF, Bennett WM (2002) Expression of apoptosisrelated genes in chronic cyclosporine nephrotoxicity in mice. Am J Transplant 2: 391-399.
28. Yu PW, Huang BC, Shen M, Quast J, Chan E, Xu X, Nolan GP, Payan DG, Luo Y (1999) Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB. Curr Biol 9: 539-542.
29. Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J (2009) RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325: 332-336.