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Volumn 4, Issue 5, 2012, Pages 868-872

Mitochondrial DNA mutations in human tumor cells (Review)

Author keywords

Germline mutation; Mitochondrial DNA; Somatic mutation; Tumor

Indexed keywords

ADENINE; CYTOCHROME C OXIDASE; CYTOSINE; FREE RADICAL; GUANINE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; THYMINE;

EID: 84866071371     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.874     Document Type: Review
Times cited : (11)

References (44)
  • 1
    • 0019423856 scopus 로고
    • Sequence and organization of the human mitochondrial genome
    • Anderson S, Bankier AT, Barrell BG, et al: Sequence and organization of the human mitochondrial genome. Nature 290: 457-465, 1981.
    • (1981) Nature , vol.290 , pp. 457-465
    • Anderson, S.1    Bankier, A.T.2    Barrell, B.G.3
  • 3
    • 0030881789 scopus 로고    scopus 로고
    • Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells
    • Croteau DL and Bohr VA: Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J Biol Chem 272: 25409-25412, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 25409-25412
    • Croteau, D.L.1    Bohr, V.A.2
  • 4
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • Yakes FM and Van Houten B: Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 94: 514-519, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 514-519
    • Yakes, F.M.1    Van Houten, B.2
  • 6
    • 0033901422 scopus 로고    scopus 로고
    • MtDNA substitution rate and segregation of heteroplasmy in coding and noncoding regions
    • Cavelier L, Jazin E, Jalonen P and Gyllensten U: MtDNA substitution rate and segregation of heteroplasmy in coding and noncoding regions. Hum Genet 107: 45-50, 2000.
    • (2000) Hum Genet , vol.107 , pp. 45-50
    • Cavelier, L.1    Jazin, E.2    Jalonen, P.3    Gyllensten, U.4
  • 7
    • 0028574053 scopus 로고
    • Mitochondrial DNA sequence variation in human evolution and disease
    • Wallace DC: Mitochondrial DNA sequence variation in human evolution and disease. Proc Natl Acad Sci USA 91: 8739-8746, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8739-8746
    • Wallace, D.C.1
  • 8
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O: On the origin of cancer cells. Science 123: 309-314, 1956.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 9
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR and Reed JC: Mitochondria and apoptosis. Science 281: 1309-1312, 1998.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 10
    • 0037364314 scopus 로고    scopus 로고
    • A role for mitochondrial enzymes in inherited neoplasia and beyond
    • Eng C, Kiuru M, Fernandez MJ and Aaltonen LA: A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat Rev Cancer 3: 193-202, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 193-202
    • Eng, C.1    Kiuru, M.2    Fernandez, M.J.3    Aaltonen, L.A.4
  • 12
    • 0032729633 scopus 로고    scopus 로고
    • Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability
    • Habano W, Sugai T, Yoshida T and Nakamura S: Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability. Int J Cancer 83: 625-629, 1999.
    • (1999) Int J Cancer , vol.83 , pp. 625-629
    • Habano, W.1    Sugai, T.2    Yoshida, T.3    Nakamura, S.4
  • 13
    • 13144295901 scopus 로고    scopus 로고
    • Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma
    • Abnet CC, Huppi K, Carrera A, et al: Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma. BMC Cancer 4: 30, 2004.
    • (2004) BMC Cancer , vol.4 , pp. 30
    • Abnet, C.C.1    Huppi, K.2    Carrera, A.3
  • 14
    • 13644251906 scopus 로고    scopus 로고
    • Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression?
    • Aikhionbare FO, Khan M, Carey D, Okoli J and Go R: Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression? Mol Cancer 3: 30, 2004.
    • (2004) Mol Cancer , vol.3 , pp. 30
    • Aikhionbare, F.O.1    Khan, M.2    Carey, D.3    Okoli, J.4    Go, R.5
  • 15
    • 0031736203 scopus 로고    scopus 로고
    • Somatic mutations of the mitochondrial genome in human colorectal tumours
    • Polyak K, Li Y, Zhu H, et al: Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat Genet 20: 291-293, 1998.
    • (1998) Nat Genet , vol.20 , pp. 291-293
    • Polyak, K.1    Li, Y.2    Zhu, H.3
  • 16
    • 0039250954 scopus 로고    scopus 로고
    • Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
    • Fliss MS, Usadel H, Caballero OL, et al: Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287: 2017-2019, 2000.
    • (2000) Science , vol.287 , pp. 2017-2019
    • Fliss, M.S.1    Usadel, H.2    Caballero, O.L.3
  • 17
    • 0035501563 scopus 로고    scopus 로고
    • Detection of mitochondrial DNA alterations in primary tumors and corresponding serum of colorectal cancer patients
    • Hibi K, Nakayama H, Yamazaki T, et al: Detection of mitochondrial DNA alterations in primary tumors and corresponding serum of colorectal cancer patients. Int J Cancer 94: 429-431, 2001.
    • (2001) Int J Cancer , vol.94 , pp. 429-431
    • Hibi, K.1    Nakayama, H.2    Yamazaki, T.3
  • 18
    • 1542615082 scopus 로고    scopus 로고
    • Comprehensive scanning of somatic mitochondrial DNA alterations in acute leukemia developing from myelodysplastic syndromes
    • Linnartz B, Anglmayer R and Zanssen S: Comprehensive scanning of somatic mitochondrial DNA alterations in acute leukemia developing from myelodysplastic syndromes. Cancer Res 64: 1966-1971, 2004.
    • (2004) Cancer Res , vol.64 , pp. 1966-1971
    • Linnartz, B.1    Anglmayer, R.2    Zanssen, S.3
  • 19
    • 0347627375 scopus 로고    scopus 로고
    • Frequent somatic mutations of mitochondrial DNA in esophageal squamous cell carcinoma
    • Kumimoto H, Yamane Y, Nishimoto Y, et al: Frequent somatic mutations of mitochondrial DNA in esophageal squamous cell carcinoma. Int J Cancer 108: 228-231, 2004.
    • (2004) Int J Cancer , vol.108 , pp. 228-231
    • Kumimoto, H.1    Yamane, Y.2    Nishimoto, Y.3
  • 20
    • 79959592889 scopus 로고    scopus 로고
    • Uncovering the profile of somatic mtDNA mutations in Chinese colorectal cancer patients
    • Wang CY, Li H, Hao XD, et al: Uncovering the profile of somatic mtDNA mutations in Chinese colorectal cancer patients. PLoS One 6: e21613, 2011.
    • (2011) PLoS One , vol.6
    • Wang, C.Y.1    Li, H.2    Hao, X.D.3
  • 21
    • 34548064910 scopus 로고    scopus 로고
    • Somatic mutations of mitochondrial genome in early stage breast cancer
    • Wang CY, Wang HW, Yao YG, Kong QP and Zhang YP: Somatic mutations of mitochondrial genome in early stage breast cancer. Int J Cancer 121: 1253-1256, 2007.
    • (2007) Int J Cancer , vol.121 , pp. 1253-1256
    • Wang, C.Y.1    Wang, H.W.2    Yao, Y.G.3    Kong, Q.P.4    Zhang, Y.P.5
  • 22
    • 79954596286 scopus 로고    scopus 로고
    • Rapid identification of mtDNA somatic mutations in gastric cancer tissues based on the mtDNA phylogeny
    • Bi R, Li WL, Chen MQ, Zhu Z and Yao YG: Rapid identification of mtDNA somatic mutations in gastric cancer tissues based on the mtDNA phylogeny. Mutat Res 709-710: 15-20, 2011.
    • (2011) Mutat Res , vol.709-710 , pp. 15-20
    • Bi, R.1    Li, W.L.2    Chen, M.Q.3    Zhu, Z.4    Yao, Y.G.5
  • 23
    • 0030839865 scopus 로고    scopus 로고
    • Oxidative decay of DNA
    • Beckman KB and Ames BN: Oxidative decay of DNA. J Biol Chem 272: 19633-19636, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 19633-19636
    • Beckman, K.B.1    Ames, B.N.2
  • 24
    • 1542314426 scopus 로고    scopus 로고
    • Mitochondrial DNA D-loop hypervariable regions: Czech population data
    • Vanecek T, Vorel F and Sip M: Mitochondrial DNA D-loop hypervariable regions: Czech population data. Int J Legal Med 118: 14-18, 2004.
    • (2004) Int J Legal Med , vol.118 , pp. 14-18
    • Vanecek, T.1    Vorel, F.2    Sip, M.3
  • 25
    • 0031910489 scopus 로고    scopus 로고
    • Location and frequency of polymorphic positions in the mtDNA control region of individuals from Germany
    • Lutz S, Weisser HJ, Heizmann J and Pollak S: Location and frequency of polymorphic positions in the mtDNA control region of individuals from Germany. Int J Legal Med 111: 67-77, 1998.
    • (1998) Int J Legal Med , vol.111 , pp. 67-77
    • Lutz, S.1    Weisser, H.J.2    Heizmann, J.3    Pollak, S.4
  • 26
    • 0033804530 scopus 로고    scopus 로고
    • Hypervariable sites in the mtDNA control region are mutational hotspots
    • Stoneking M: Hypervariable sites in the mtDNA control region are mutational hotspots. Am J Hum Genet 67: 1029-1032, 2000.
    • (2000) Am J Hum Genet , vol.67 , pp. 1029-1032
    • Stoneking, M.1
  • 27
    • 0034972303 scopus 로고    scopus 로고
    • High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection
    • Coller HA, Khrapko K, Bodyak ND, Nekhaeva E, Herrero-Jimenez P and Thilly WG: High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat Genet 28: 147-150, 2001.
    • (2001) Nat Genet , vol.28 , pp. 147-150
    • Coller, H.A.1    Khrapko, K.2    Bodyak, N.D.3    Nekhaeva, E.4    Herrero-Jimenez, P.5    Thilly, W.G.6
  • 28
    • 0035866352 scopus 로고    scopus 로고
    • Detection of mitochondrial DNA mutations in pancreatic cancer offers a 'mass'-ive advantage over detection of nuclear DNA mutations
    • Jones JB, Song JJ, Hempen PM, Parmigiani G, Hruban RH and Kern SE: Detection of mitochondrial DNA mutations in pancreatic cancer offers a 'mass'-ive advantage over detection of nuclear DNA mutations. Cancer Res 61: 1299-1304, 2001.
    • (2001) Cancer Res , vol.61 , pp. 1299-1304
    • Jones, J.B.1    Song, J.J.2    Hempen, P.M.3    Parmigiani, G.4    Hruban, R.H.5    Kern, S.E.6
  • 29
    • 0037180245 scopus 로고    scopus 로고
    • Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: Is there a common mechanism?
    • Chinnery PF, Samuels DC, Elson J and Turnbull DM: Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism? Lancet 360: 1323-1325, 2002.
    • (2002) Lancet , vol.360 , pp. 1323-1325
    • Chinnery, P.F.1    Samuels, D.C.2    Elson, J.3    Turnbull, D.M.4
  • 30
    • 1442303118 scopus 로고    scopus 로고
    • mtDNA mutations in tumors of the central nervous system reflect the neutral evolution of mtDNA in populations
    • Vega A, Salas A, Gamborino E, Sobrido MJ, Macaulay V and Carracedo A: mtDNA mutations in tumors of the central nervous system reflect the neutral evolution of mtDNA in populations. Oncogene 23: 1314-1320, 2004.
    • (2004) Oncogene , vol.23 , pp. 1314-1320
    • Vega, A.1    Salas, A.2    Gamborino, E.3    Sobrido, M.J.4    McAulay, V.5    Carracedo, A.6
  • 31
    • 78649794554 scopus 로고    scopus 로고
    • Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients
    • Kloss-Brandstätter A, Schäfer G, Erhart G, et al: Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients. Am J Hum Genet 87: 802-812, 2011.
    • (2011) Am J Hum Genet , vol.87 , pp. 802-812
    • Kloss-Brandstätter, A.1    Schäfer, G.2    Erhart, G.3
  • 32
    • 80051570214 scopus 로고    scopus 로고
    • Somatic mutations of the mitochondrial genome in human breast cancers
    • Tseng LM, Yin PH, Yang CW, et al: Somatic mutations of the mitochondrial genome in human breast cancers. Genes Chromosomes Cancer 50: 800-811, 2011.
    • (2011) Genes Chromosomes Cancer , vol.50 , pp. 800-811
    • Tseng, L.M.1    Yin, P.H.2    Yang, C.W.3
  • 33
    • 16644383274 scopus 로고    scopus 로고
    • Less deltamtDNA4977 than normal in various types of tumors suggests that cancer cells are essentially free of this mutation
    • Dani MA, Dani SU, Lima SP, et al: Less deltamtDNA4977 than normal in various types of tumors suggests that cancer cells are essentially free of this mutation. Genet Mol Res 3: 395-409, 2004.
    • (2004) Genet Mol Res , vol.3 , pp. 395-409
    • Dani, M.A.1    Dani, S.U.2    Lima, S.P.3
  • 34
    • 84855275503 scopus 로고    scopus 로고
    • Mitochondrial DNA content varies with pathological characteristics of breast cancer
    • Bai RK, Chang J, Yeh KT, et al: Mitochondrial DNA content varies with pathological characteristics of breast cancer. J Oncol 2011: 496189, 2011.
    • (2011) J Oncol , vol.2011 , pp. 496189
    • Bai, R.K.1    Chang, J.2    Yeh, K.T.3
  • 35
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks PC, Montgomery AM, Rosenfeld M, et al: Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79: 1157-1164, 1994.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3
  • 36
    • 0017341618 scopus 로고
    • Avascular and vascular phases of tumour growth in the chick embryo
    • Knighton D, Ausprunk D, Tapper D and Folkman J: Avascular and vascular phases of tumour growth in the chick embryo. Br J Cancer 35: 347-356, 1977.
    • (1977) Br J Cancer , vol.35 , pp. 347-356
    • Knighton, D.1    Ausprunk, D.2    Tapper, D.3    Folkman, J.4
  • 37
    • 0026697079 scopus 로고
    • Recovery of the missing tumorigenicity in mitochondrial DNA-less HeLa cells by introduction of mitochondrial DNA from normal human cells
    • Hayashi J, Takemitsu M and Nonaka I: Recovery of the missing tumorigenicity in mitochondrial DNA-less HeLa cells by introduction of mitochondrial DNA from normal human cells. Somat Cell Mol Genet 18: 123-129, 1992.
    • (1992) Somat Cell Mol Genet , vol.18 , pp. 123-129
    • Hayashi, J.1    Takemitsu, M.2    Nonaka, I.3
  • 38
    • 0034213186 scopus 로고    scopus 로고
    • The evolution of free radicals and oxidative stress
    • McCord JM: The evolution of free radicals and oxidative stress. Am J Med 108: 652-659, 2000.
    • (2000) Am J Med , vol.108 , pp. 652-659
    • McCord, J.M.1
  • 39
    • 0030764341 scopus 로고    scopus 로고
    • Expression of antioxidant enzymes in human prostatic adenocarcinoma
    • Baker AM, Oberley LW and Cohen MB: Expression of antioxidant enzymes in human prostatic adenocarcinoma. Prostate 32: 229-233, 1997.
    • (1997) Prostate , vol.32 , pp. 229-233
    • Baker, A.M.1    Oberley, L.W.2    Cohen, M.B.3
  • 40
    • 0034234580 scopus 로고    scopus 로고
    • Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer
    • Bostwick DG, Alexander EE, Singh R, et al: Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer. Cancer 89: 123-134, 2000.
    • (2000) Cancer , vol.89 , pp. 123-134
    • Bostwick, D.G.1    Alexander, E.E.2    Singh, R.3
  • 42
    • 20044364344 scopus 로고    scopus 로고
    • mtDNA mutations increase tumorigenicity in prostate cancer
    • Petros JA, Baumann AK, Ruiz-Pesini E, et al: mtDNA mutations increase tumorigenicity in prostate cancer. Proc Natl Acad Sci USA 102: 719-724, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 719-724
    • Petros, J.A.1    Baumann, A.K.2    Ruiz-Pesini, E.3
  • 43
    • 16444386967 scopus 로고    scopus 로고
    • Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis
    • Shidara Y, Yamagata K, Kanamori T, et al: Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Res 65: 1655-1663, 2005.
    • (2005) Cancer Res , vol.65 , pp. 1655-1663
    • Shidara, Y.1    Yamagata, K.2    Kanamori, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.