Hyperoxia resensitizes chemoresistant human glioblastoma cells to Temozolomide

Journal of Neuro-Oncology

Volumn 109, Issue 3, 2012, Pages 467-475

  Sun, Stella ^a   Lee, Derek ^a   Lee, Nikki P ^a   Pu, Jenny K S ^a   Wong, Stanley T S ^a   Lui, W M ^a   Fung, C F ^a   Leung, Gilberto K K ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Chemoresistance; Glioma; Hypoxia; MAPK; Temozolomide

Indexed keywords

CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYGEN; TEMOZOLOMIDE;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL DEATH; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HYPEROXIA; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINE, TUMOR; DACARBAZINE; DRUG RESISTANCE, NEOPLASM; GLIOBLASTOMA; HUMANS; HYPEROXIA; MITOGEN-ACTIVATED PROTEIN KINASE KINASES;

EID: 84866053232     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-012-0923-3     Document Type: Article

References (50)

1. Norden AD, Wen PY (2006) Glioma therapy in adults. Neurologist 12:279-292 (Pubitemid 44813664)
2. Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, Hau P, Brandes AA, Gijtenbeek J, Marosi C, Vecht CJ, Mokhtari K, Wesseling P, Villa S, Eisenhauer E, Gorlia T, Weller M, Lacombe D, Cairncross JG, Mirimanoff RO (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10:459-466
3. Auger N, Thillet J, Wanherdrick K, Idbaih A, Legrier ME, Dutrillaux B, Sanson M, Poupon MF (2006) Genetic alterations associated with acquired temozolomide resistance in SNB-19, a human glioma cell line. Mol Cancer Ther 5:2182-2192 (Pubitemid 44530454)
4. de Saldanha da Gama Fischer J, Costa Carvalho P, da Fonseca CO, Liao L, Degrave WM, da Gloria da Costa Carvalho M, Yates JR, Domont GB (2011) Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol. J Proteome Res 10:153-160
5. Chakravarti A, Palanichamy K (2008) Overcoming therapeutic resistance in malignant gliomas: current practices and future directions. Cancer Treat Res 139:173-189
6. Chinot OL, de La Motte Rouge T, Moore N, Zeaiter A, Das A, Phillips H, Modrusan Z, Cloughesy T (2011) AVAglio: phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme. Adv Ther 28:334-340
7. Singhal AB (2007) A review of oxygen therapy in ischemic stroke. Neurol Res 29:173-183 (Pubitemid 46685270)
8. Kumaria A, Tolias CM (2009) Normobaric hyperoxia therapy for traumatic brain injury and stroke: a review. Br J Neurosurg 23:576-584
9. Tolias CM, Kumaria A, Bullock MR (2009) Hyperoxia and traumatic brain injury. J Neurosurg 110:607-609; author reply 609-611
10. Tatarkova Z, Engler I, Calkovska A, Mokra D, Drgova A, Hodas P, Lehotsky J, Dobrota D, Kaplan P (2011) Effect of long-term normobaric hyperoxia on oxidative stress in mitochondria of the guinea pig brain. Neurochem Res 36:1475-1481
11. Konsavage WM, Zhang L, Wu Y, Shenberger JS (2012) Hyperoxiainduced activation of the integrated stress response in the newborn rat lung. Am J Physiol Lung Cell Mol Physiol 302:L27-L35
12. Amberger-Murphy V (2009) Hypoxia helps glioma to fight therapy. Curr Cancer Drug Targets 9:381-390
13. Brat DJ, Mapstone TB (2003) Malignant glioma physiology: cellular response to hypoxia and its role in tumor progression. Ann Intern Med 138:659-668 (Pubitemid 38124658)
14. Stuhr LE, Iversen VV, Straume O, Maehle BO, Reed RK (2004) Hyperbaric oxygen alone or combined with 5-FU attenuates growth of DMBA-induced rat mammary tumors. Cancer Lett 210:35-40 (Pubitemid 38692585)
15. Alagoz T, Buller RE, Anderson B, Terrell KL, Squatrito RC, Niemann TH, Tatman DJ, Jebson P (1995) Evaluation of hyperbaric oxygen as a chemosensitizer in the treatment of epithelial ovarian cancer in xenografts in mice. Cancer 75:2313-2322
16. Stuhr LE, Raa A, Oyan AM, Kalland KH, Sakariassen PO, Petersen K, Bjerkvig R, Reed RK (2007) Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats. J Neurooncol 85:191-202 (Pubitemid 47629400)
17. D'Agostino DP, Olson JE, Dean JB (2009) Acute hyperoxia increases lipid peroxidation and induces plasma membrane blebbing in human U87 glioblastoma cells. Neuroscience 159:1011-1022
18. Sun S, Wong TS, Zhang XQ, Pu JK, Lee NP, Day PJ, Ng GK, Lui WM, Leung GK (2012) Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines. J Neurooncol 107:89-100
19. Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG (1999) Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 59:793-797 (Pubitemid 29086728)
20. Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352:997-1003 (Pubitemid 40349502)
21. Bocangel DB, Finkelstein S, Schold SC, Bhakat KK, Mitra S, Kokkinakis DM (2002) Multifaceted resistance of gliomas to temozolomide. Clin Cancer Res 8:2725-2734 (Pubitemid 34856362)
22. Oliva CR, Nozell SE, Diers A, McClugage SG 3rd, Sarkaria JN, Markert JM, Darley-Usmar VM, Bailey SM, Gillespie GY, Landar A, Griguer CE (2010) Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. J Biol Chem 285:39759-39767
23. Le Calve B, Rynkowski M, Le Mercier M, Bruyere C, Lonez C, Gras T, Haibe-Kains B, Bontempi G, Decaestecker C, Ruysschaert JM, Kiss R, Lefranc F (2010) Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression. Neoplasia 12:727-739
24. Quinn JA, Jiang SX, Reardon DA, Desjardins A, Vredenburgh JJ, Rich JN, Gururangan S, Friedman AH, Bigner DD, Sampson JH, McLendon RE, Herndon JE 2nd, Walker A, Friedman HS (2009) Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. J Clin Oncol 27:1262-1267
25. Bar EE, Lin A, Mahairaki V, Matsui W, Eberhart CG (2010) Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. Am J Pathol 177:1491-1502
26. Pistollato F, Abbadi S, Rampazzo E, Persano L, Della Puppa A, Frasson C, Sarto E, Scienza R, D'Avella D, Basso G (2010) Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. Stem Cells 28:851-862
27. Li L, Lin X, Staver M, Shoemaker A, Semizarov D, Fesik SW, Shen Y (2005) Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo. Cancer Res 65:7249-7258 (Pubitemid 41161256)
28. Semenza GL (2003) Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3:721-732 (Pubitemid 37328811)
29. Lu Y, Li X, Lu H, Fan Z (2010) 1, 9-Pyrazoloanthrones downregulate HIF-1alpha and sensitize cancer cells to cetuximabmediated anti-EGFR therapy. PLoS One 5:e15823
30. Pourgholami MH, Cai ZY, Badar S, Wangoo K, Poruchynsky MS, Morris DL (2010) Potent inhibition of tumoral hypoxiainducible factor 1alpha by albendazole. BMC Cancer 10:143
31. Li L, Lin X, Shoemaker AR, Albert DH, Fesik SW, Shen Y (2006) Hypoxia-inducible factor-1 inhibition in combination with temozolomide treatment exhibits robust antitumor efficacy in vivo. Clin Cancer Res 12:4747-4754 (Pubitemid 44297829)
32. Granowitz EV, Tonomura N, Benson RM, Katz DM, Band V, Makari-Judson GP, Osborne BA (2005) Hyperbaric oxygen inhibits benign and malignant human mammary epithelial cell proliferation. Anticancer Res 25:3833-3842 (Pubitemid 41665152)
33. Takiguchi N, Saito N, Nunomura M, Kouda K, Oda K, Furuyama N, Nakajima N (2001) Use of 5-FU plus hyperbaric oxygen for treating malignant tumors: evaluation of antitumor effect and measurement of 5-FU in individual organs. Cancer Chemother Pharmacol 47:11-14 (Pubitemid 32664506)
34. Moen I, Tronstad KJ, Kolmannskog O, Salvesen GS, Reed RK, Stuhr LE (2009) Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma. BMC Cancer 9:446
35. Kawasoe Y, Yokouchi M, Ueno Y, Iwaya H, Yoshida H, Komiya S (2009) Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of osteosarcoma. Oncol Rep 22:1045-1050
36. Kalns J, Krock L, Piepmeier E Jr (1998) The effect of hyperbaric oxygen on growth and chemosensitivity of metastatic prostate cancer. Anticancer Res 18:363-367 (Pubitemid 28174733)
37. Petre PM, Baciewicz FA Jr, Tigan S, Spears JR (2003) Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of metastatic lung tumors in a rat model. J Thorac Cardiovasc Surg 125:85-95; discussion 95 (Pubitemid 36120272)
38. Beppu T, Kamada K, Yoshida Y, Arai H, Ogasawara K, Ogawa A (2002) Change of oxygen pressure in glioblastoma tissue under various conditions. J Neurooncol 58:47-52 (Pubitemid 34711970)
39. Moen I, Oyan AM, Kalland KH, Tronstad KJ, Akslen LA, Chekenya M, Sakariassen PO, Reed RK, Stuhr LE (2009) Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model. PLoS One 4:e6381
40. Al-Waili NS, Butler GJ (2007) A combination of radiotherapy, nitric oxide and a hyperoxygenation sensitizing protocol for brain malignant tumor treatment. Med Hypotheses 68:528-537 (Pubitemid 46037982)
41. Beppu T, Kamada K, Nakamura R, Oikawa H, Takeda M, Fukuda T, Arai H, Ogasawara K, Ogawa A (2003) A phase II study of radiotherapy after hyperbaric oxygenation combined with interferon-beta and nimustine hydrochloride to treat supratentorial malignant gliomas. J Neurooncol 61:161-170 (Pubitemid 36258337)
42. Perez-Espejo MA, Garcia-Fernandez R, Tobarra-Gonzalez BM, Palma-Copete JD, Gonzalez-Lopez A, De la Fuente-Munoz I, Salinas-Ramos J, Felipe-Murcia M, Martinez-Lage JF, Fernandez-Perez J, Romero JM (2009) Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema after LINAC radiosurgery. Neurocirugia (Astur) 20:449-453
43. Zaher TE, Miller EJ, Morrow DM, Javdan M, Mantell LL (2007) Hyperoxia-induced signal transduction pathways in pulmonary epithelial cells. Free Radic Biol Med 42:897-908 (Pubitemid 46356904)
44. Zhang XF, Foda HD (2004) Pulmonary apoptosis and necrosis in hyperoxia-induced acute mouse lung injury. Zhonghua Jie He He Hu Xi Za Zhi 27:465-468
45. Tateda K, Deng JC, Moore TA, Newstead MW, Paine R 3rd, Kobayashi N, Yamaguchi K, Standiford TJ (2003) Hyperoxia mediates acute lung injury and increased lethality in murine Legionella pneumonia: the role of apoptosis. J Immunol 170:4209-4216 (Pubitemid 36428187)
46. O'Reilly MA, Staversky RJ, Huyck HL, Watkins RH, LoMonaco MB, D'Angio CT, Baggs RB, Maniscalco WM, Pryhuber GS (2000) Bcl-2 family gene expression during severe hyperoxia induced lung injury. Lab Invest 80:1845-1854 (Pubitemid 32012753)
47. Romashko J 3rd, Horowitz S, Franek WR, Palaia T, Miller EJ, Lin A, Birrer MJ, Scott W, Mantell LL (2003) MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells. Free Radic Biol Med 35:978-993 (Pubitemid 37211452)
48. Seger R, Krebs EG (1995) The MAPK signaling cascade. FASEB J 9:726-735
49. Buckley S, Driscoll B, Barsky L, Weinberg K, Anderson K, Warburton D (1999) ERK activation protects against DNA damage and apoptosis in hyperoxic rat AEC2. Am J Physiol 277:L159-L166 (Pubitemid 29356763)
50. Petrache I, Choi ME, Otterbein LE, Chin BY, Mantell LL, Horowitz S, Choi AM (1999) Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells. Am J Physiol 277:L589-L595 (Pubitemid 29459679)