Evaluation of in vivo wound healing activity of methanol extract of Achyranthes aspera L.

Journal of Ethnopharmacology

Volumn 143, Issue 2, 2012, Pages 469-474

  Fikru, Abraham ^a   Makonnen, Eyasu ^b   Eguale, Tadesse ^c   Debella, Asfaw ^d   Abie Mekonnen, Getinet ^e  

^a UNIVERSITY OF GONDAR   (Ethiopia)

^b ADDIS ABABA UNIVERSITY   (Ethiopia)

^c ADDIS ABABA UNIVERSITY   (Ethiopia)

^d ETHIOPIAN PUBLIC HEALTH INSTITUTE   (Ethiopia)

^e National Animal Health Diagnostic and Investigation Center   (Ethiopia)

Author keywords

Achyranthes aspera L.; In vivo; Methanol; Rats; Wound healing

Indexed keywords

ACHYRANTHES ASPERA EXTRACT; ETHER; SULFADIAZINE SILVER; WOUND HEALING PROMOTING AGENT;

ACHYRANTHES ASPERA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA CONTENT; EPIDERMIS; EPITHELIZATION; EXCISION; FEMALE; IN VIVO STUDY; INCISION; MALE; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; RAT; WOUND CONTRACTION; WOUND HEALING;

ACHYRANTHES; ANIMALS; DNA; ETHIOPIA; FEMALE; MALE; MEDICINE, AFRICAN TRADITIONAL; METHANOL; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; SKIN; SOLVENTS; WOUND HEALING;

ACHYRANTHES ASPERA; ANIMALIA; RATTUS;

EID: 84866050827     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.06.049     Document Type: Article

References (36)

1. M. Balick, and P.A. Cox Plants, People and Culture: The Science of Ethnobotany 1996 Scientific American Library, W.H. Freeman and Company New York pp. 124-147
2. C.C. Barua, A. Talukdar, S.A. Begum, L.C. Lahon, D.K. Sarma, D.K. Patha, and P. Borah Antinociceptive activity of methanolic extract of leaves of Achyranthes aspera Linn. (Amaranthaceae) in animal models of nociception Indian Journal of Experimental Biology 48 2010 817 821
3. N.K. Basu, N.C. Neogi, and V.P. Srivastava Biological investigation of Achyranthes aspera Linn. and its constituent achyranthine Journal and Proceedings of the Institute of Chemistry of Great Britain 29 1957 161 165
4. P. Chithra, G.B. Sajithlal, and G. Chandrakasan Influence of Aloe vera on the healing of dermal wounds in diabetic rats Journal of Ethnopharmacology 59 1998 195 201
5. P. Chithra, G.B. Sajithlal, and G. Chandrakasan Influence of Aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats Journal of Ethnopharmacology 59 1998 179 186
6. R.A.F. Clark Wound repair: overview and general consideration R.A. Clark, P.M. Henson, Molecular and Cellular Biology of Wound Repair 1996 The Plenum Press New York 473 488
7. A. Debella Manual for phytochemical screening of medicinal plants. Department of drug research 2002 Ethiopian Health and Nutrition Research Institute (EHNRI) Ethiopia pp. 15-24
8. C.O. Esimone, C.S. Nworu, and C.L. Jackson Cutaneous wound healing activity of a herbal ointment containing the leaf extract of Jatropha curcas L. (Euphorbiaceae) International Journal of Applied Research in Natural Products 1 2008 1 4
9. European Community guidelines (EEC Directive of 1986; 86/609/EEC). Council directive of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes (86/609/EEC).
10. M. Fisseha, D. Sebsebe, and T. Tilahun An ethnobotanical study of medicinal plants in Wonago Woreda, SNNPR, Ethiopia Journal of Ethnobiology and Ethnomedicine 5 2009 1 18
11. Gaur, R.; Azizi, M.; Gan, J.; Hansal, P.; Harper, K.; Mannan, R.; Panchal, A.; Patel, K.; Patel, M.; Patel, N.; Rana, J.; Rogowska, A.; 2009. Simple ointment: formulated preparations. British Pharmacopoeia, Crown, Inc. London, vol. 3. pp. 9983.
12. M. George, P.R. Venkataraman, and K.M. Pandalai Investigations on plant antibiotics: Part II. A search for antibiotic substances in some Indian medicinal plants Journal of Scientific and Industrial Research 6B 1947 42 46
13. M. Giday, Z. Asfaw, T. Elmqvist, and Z. Woldu An ethnobotanical study of medicinal plants used by the Zay people in Ethiopia Journal of Ethnopharmacology 85 2003 43 52
14. M. Giday, T. Teklehaymanot, A. Animut, and Y. Mekonnen Medicinal plants of the Shinasha, Agew-awi and Amhara peoples in northwest Ethiopia Journal of Ethnopharmacology 110 2007 516 525
15. R.A. Govindarajan, P. Pushpangadan, B. Kumara, and M. Vijayakumar Ethnopharmacological approaches to wound healing - exploring medicinal plants of India Journal of Ethnopharmacology 114 2007 103 113
16. B.P. Latha, R.M. Reddy, S.M. Ismail, and T. Vijaya Medicinal plants and their derivatives as potential source in treatment of obesity Asian Journal of Experimental Biological Sciences 1 2010 719 727
17. K.H. Lee Studies on mechanism of action of salicylates: retardation of wound healing by aspirin Journal of Pharmaceutical Sciences 57 1968 1042 1043
18. M.G. Letts, L.F. Villegas, A. Marcalo, A.J. Vaisberg, and G.B. Hammond In vivo wound healing activity of olanolic acid derived from the acid hydrolysis of Andredera diffusa Journal of Natural Products 69 2006 978 979
19. Z.Q. Lin, T. Kondo, Y. Ishida, T. Takayasu, and N. Mukaida Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing Journal of Leukocyte Biology 73 2003 713 772
20. A.A. Martin The use of antioxidants in healing Dermatological Surgery 22 1996 156 160
21. C. Muthu, M. Ayyanar, N. Raja, and S. Ignacimuthu Medicinal plants used by traditional healers in Kancheepuram district of Tamil Nadu, India Journal of Ethnobiology and Ethnomedicine 2 2006 1 10
22. J.Y. Nehete, V.N. Deshmukh, V.V. Shewale, M.R. Narkhede, and V.M. Aurangabadkar In vitro antioxidant activity of Achyranthes aspera L Journal of Pharmacy Research 2 2009 1402 1403
23. G.N. Njoroge, and R.W. Bussmann Ethnotherapeautic management of skin diseases among the Kikuyus of Central Kenya Journal of Ethnopharmacology 111 2007 303 307
24. I. Pesin Suntar, E. Kupeli Akkol, D. Ylmazer, T. Baykal, H. Kirmizibekmez, M. Alper, and E. Yesilada Investigations on the in vivo wound healing potential of Hypericum perforatum L Journal of Ethnopharmacology 127 2010 468 477
25. M.P. Rosa, and V.S. Rosario Anti-inflammatory and wound healing potential of Prosthechea michuacana in rats Pharmacognosy Magazine 5 2009 219 222
26. M. Scortichini, and R.M. Pia Preliminary in vitro evaluation of the antimicrobial activity of terpenes and terpenoids towards Erwinia amylovora (Burrill) Journal of Applied Bacteriology 71 1991 109 112
27. R.R. Shenoy, A.T. Sudheendra, P.G. Nayak, P. Paul, N.G. Kutty, and C.M. Rao Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats Journal of Ethnopharmacology 133 2011 608 612
28. A. Sirak, and G. Abie Manual of standard operating procedure (SOP) for tissue processing 2009 National Animal Health and Investigation Center (NAHDIC) Ethiopia pp. 8-32
29. W.M. Strauss Preparation of genomic DNA from mammalian tissue F.M. Ausubel, R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, Current Protocols in Molecular Biology 2003 John Wiley and Sons Inc. 198 220
30. D. Sumeet, D. Raghvendra, and M. Kushagra Achyranthes aspera Linn. (Chirchira): a magic herb in folk medicine Ethnobotanical Leaflets 12 2008 670 676
31. K. Sushil, G.D. Bagchi, and M.P. Darokar Antibacterial activity observed in the seeds of some coprophilous plants International Journal of Pharmacognosy 35 1997 179 184
32. T. Teklehaymanot, and M. Giday Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia Journal of Ethnobiology and Ethnomedicine 3 2007 1 11
33. T. Teklehaymanot, M. Giday, G. Medhin, and Y. Mekonnen Knowledge and use of medicinal plants by people around Debre Libanos monastery in Ethiopia Journal of Ethnopharmacology 111 2007 271 283
34. A.L. Udupa, D.R. Kulkarni, and S.L. Udupa Effect of Tridax procumbens extracts on wound healing International Journal of Pharmacognosy 33 1995 37 40
35. R. Valsaraj, P. Pushpangadan, U.W. Smitt, A. Andersen, and U. Nyman Antimicrobial screening of selected medicinal plants from India Journal of Ethnopharmacology 58 1997 75 83
36. ®, increases macrophage phagocytosis and nitric oxide production and increases circulating human lymphocytes levels Medical Science Monitor 15 2009 43 46