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Volumn 13, Issue 9, 2012, Pages 695-706

Impairment of liver regeneration by the histone deacetylase inhibitor valproic acid in mice

Author keywords

B myc; Cell cycle; Epigenetic factors; Liver regeneration; VPA

Indexed keywords

BROXURIDINE; COMPLEMENTARY DNA; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; HISTONE DEACETYLASE; KI 67 ANTIGEN; MYC PROTEIN; VALPROIC ACID;

EID: 84866045219     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B1100362     Document Type: Article
Times cited : (14)

References (41)
  • 1
    • 0028895215 scopus 로고
    • Mouse and rat B-myc share amino acid sequence homology with the C-myc transcriptional activator domain and contain a B-myc specific carboxyl terminal region
    • Asker, C., Magnusson, K.P., Piccoli, S.P., Andersson, K., Klein, G., Cole, M.D., Wiman, K.G., 1995. Mouse and rat B-myc share amino acid sequence homology with the C-myc transcriptional activator domain and contain a B-myc specific carboxyl terminal region. Oncogene, 11(10):1963-1969.
    • (1995) Oncogene , vol.11 , Issue.10 , pp. 1963-1969
    • Asker, C.1    Magnusson, K.P.2    Piccoli, S.P.3    Andersson, K.4    Klein, G.5    Cole, M.D.6    Wiman, K.G.7
  • 2
    • 0033922278 scopus 로고    scopus 로고
    • Cell cycle control during liver development in the rat: Evidence indicating a role for cyclin D1 posttranscriptional regulation 1
    • Awad, M.M., Gruppuso, P.A., 2000. Cell cycle control during liver development in the rat: evidence indicating a role for cyclin D1 posttranscriptional regulation 1. Cell Growth Differ., 11(6):325-334.
    • (2000) Cell Growth Differ. , vol.11 , Issue.6 , pp. 325-334
    • Awad, M.M.1    Gruppuso, P.A.2
  • 4
    • 33747476839 scopus 로고    scopus 로고
    • B-myc: N-terminal recognition of myc binding proteins
    • [doi:10.1021/bi060379n]
    • Burton, R.A., Mattila, S., Taparowsky, E.J., Post, C.B., 2006. B-myc: N-terminal recognition of myc binding proteins. Biochemistry, 45(32):9857-9865. [doi:10.1021/bi060379n]
    • (2006) Biochemistry , vol.45 , Issue.32 , pp. 9857-9865
    • Burton, R.A.1    Mattila, S.2    Taparowsky, E.J.3    Post, C.B.4
  • 5
    • 0032477854 scopus 로고    scopus 로고
    • Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
    • [doi:10.1073/pnas.95.3.1091]
    • Cheng, M., Sexl, V., Sherr, C.J., Roussel, M.F., 1998. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). PNAS, 95(3):1091-1096. [doi:10.1073/pnas.95.3. 1091]
    • (1998) PNAS , vol.95 , Issue.3 , pp. 1091-1096
    • Cheng, M.1    Sexl, V.2    Sherr, C.J.3    Roussel, M.F.4
  • 6
    • 79955055539 scopus 로고    scopus 로고
    • Introduction - Epiphanies in epigenetics
    • [doi:10.1016/B978-0-12-387685-000001-000009
    • Cheng, X., Blumenthal, R.M., 2011. Introduction - epiphanies in epigenetics. Prog. Mol. Biol. Transl. Sci., 101:1-21. [doi:10.1016/B978-0-12- 387685-0.00001-9.
    • (2011) Prog. Mol. Biol. Transl. Sci. , vol.101 , pp. 1-21
    • Cheng, X.1    Blumenthal, R.M.2
  • 7
    • 0035011306 scopus 로고    scopus 로고
    • B-myc, a proximal caput epididymal protein, is dependent on androgens and testicular factors for expression
    • [doi:10.1095/biolreprod64.6.1600]
    • Cornwall, G.A., Collis, R., Xiao, Q., Hsia, N., Hann, S.R., 2001. B-myc, a proximal caput epididymal protein, is dependent on androgens and testicular factors for expression. Biol. Reprod., 64(6):1600-1607. [doi:10.1095/ biolreprod64.6.1600]
    • (2001) Biol. Reprod. , vol.64 , Issue.6 , pp. 1600-1607
    • Cornwall, G.A.1    Collis, R.2    Xiao, Q.3    Hsia, N.4    Hann, S.R.5
  • 8
    • 0031806044 scopus 로고    scopus 로고
    • The molecular role of myc in growth and transformation: Recent discoveries lead to new insights
    • Facchini, L.M., Penn, L.Z., 1998. The molecular role of myc in growth and transformation: recent discoveries lead to new insights. FASEB J., 12(9):633-651.
    • (1998) FASEB J. , vol.12 , Issue.9 , pp. 633-651
    • Facchini, L.M.1    Penn, L.Z.2
  • 9
    • 0034007745 scopus 로고    scopus 로고
    • Liver regeneration
    • [doi101016/S0168-82780080412-80412
    • Fausto, N., 2000. Liver regeneration. J. Hepatol., 32(1 Suppl.): 19-31. [doi:10.1016/S0168-8278(00)80412-2.
    • (2000) J. Hepatol. , vol.32 , Issue.1 SUPPL. , pp. 19-31
    • Fausto, N.1
  • 10
    • 79957791258 scopus 로고    scopus 로고
    • Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases
    • [doi:10.1007/s00534-010-0304-0312
    • Fujiyoshi, M., Ozaki, M., 2011. Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases. J. Hepatobilliary Pancreat. Sci., 18(1):13-22. [doi:10.1007/s00534-010-0304-2.
    • (2011) J. Hepatobilliary Pancreat. Sci. , vol.18 , Issue.1 , pp. 13-22
    • Fujiyoshi, M.1    Ozaki, M.2
  • 11
    • 0034609752 scopus 로고    scopus 로고
    • B-myc is preferentially expressed in hormonally-controlled tissues and inhibits cellular proliferation
    • [doi:10.1038/sj. onc.1203851]
    • Gregory, M.A., Xiao, Q., Cornwall, G.A., Lutterbach, B., Hann, S.R., 2000. B-myc is preferentially expressed in hormonally-controlled tissues and inhibits cellular proliferation. Oncogene, 19(42):4886-4895. [doi:10.1038/sj. onc.1203851]
    • (2000) Oncogene , vol.19 , Issue.42 , pp. 4886-4895
    • Gregory, M.A.1    Xiao, Q.2    Cornwall, G.A.3    Lutterbach, B.4    Hann, S.R.5
  • 12
    • 0842325787 scopus 로고    scopus 로고
    • Histone deacetylase is a target of valproic acid-mediated cellular differentiation
    • [doi101158/0008-5472CAN-03-0799
    • Gurvich, N., Tsygankova, O.M., Meinkoth, J.L., Klein, P.S., 2004. Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res., 64(3):1079-1086. [doi:10.1158/0008-5472.CAN-03-0799.
    • (2004) Cancer Res. , vol.64 , Issue.3 , pp. 1079-1086
    • Gurvich, N.1    Tsygankova, O.M.2    Meinkoth, J.L.3    Klein, P.S.4
  • 13
    • 0001276586 scopus 로고
    • Experimental pathology of the liver: Restoration of the liver of the white rat following partial surgical removal
    • Higgins, G.M., Anderson, R.M., 1931. Experimental pathology of the liver: restoration of the liver of the white rat following partial surgical removal. Arch. Pathol., 12:186-202.
    • (1931) Arch. Pathol. , vol.12 , pp. 186-202
    • Higgins, G.M.1    Anderson, R.M.2
  • 14
    • 0023812164 scopus 로고
    • Structure and expression of B-myc, a new member of the myc gene family
    • [doi:10.1128/MCB.8.8.3168]
    • Ingvarsson, S., Asker, C., Acelson, H., Klein, G., Sumegi, J., 1988. Structure and expression of B-myc, a new member of the myc gene family. Mol. Cell. Biol., 8(8):3168-3174. [doi:10.1128/MCB.8.8.3168]
    • (1988) Mol. Cell. Biol. , vol.8 , Issue.8 , pp. 3168-3174
    • Ingvarsson, S.1    Asker, C.2    Acelson, H.3    Klein, G.4    Sumegi, J.5
  • 15
    • 33644554220 scopus 로고    scopus 로고
    • The effects of the histone deacetylase inhibitor valproic acid on cell cycle, growth suppression and apoptosis in multiple myeloma
    • Kaiser, M., Zavrski, I., Sterz, J., Jakob, C., Fleissner, C., Kloetzel, P.M., Sezer, O., Heider, U., 2006. The effects of the histone deacetylase inhibitor valproic acid on cell cycle, growth suppression and apoptosis in multiple myeloma. Haematologica, 91(2):248-251.
    • (2006) Haematologica , vol.91 , Issue.2 , pp. 248-251
    • Kaiser, M.1    Zavrski, I.2    Sterz, J.3    Jakob, C.4    Fleissner, C.5    Kloetzel, P.M.6    Sezer, O.7    Heider, U.8
  • 16
    • 79957561752 scopus 로고    scopus 로고
    • Epigenetic reprogramming during tissue regeneration
    • [doi:10.1016/j.febslet.2011.05.010]
    • Katsuyama, T., Paro, R., 2011. Epigenetic reprogramming during tissue regeneration. FEBS Lett., 585(11):1617-1624. [doi:10.1016/j.febslet.2011.05.010]
    • (2011) FEBS Lett. , vol.585 , Issue.11 , pp. 1617-1624
    • Katsuyama, T.1    Paro, R.2
  • 17
    • 34249774867 scopus 로고    scopus 로고
    • Clinicopathologic features of pleomorphic hyalinizing angiectatic tumor of soft parts
    • Ke, Q., Erbolat, Zhang, H.Y., Bu, H., Li, S., Shi, D.N., Yang, G.H., Chen, H.J., Wei, B., 2007. Clinicopathologic features of pleomorphic hyalinizing angiectatic tumor of soft parts. Chin. Med. J., 120(10):876-881.
    • (2007) Chin. Med. J. , vol.120 , Issue.10 , pp. 876-881
    • Ke, Q.1    Erbolat Zhang, H.Y.2    Bu, H.3    Li, S.4    Shi, D.N.5    Yang, G.H.6    Chen, H.J.7    Wei, B.8
  • 18
    • 79958292800 scopus 로고    scopus 로고
    • Profiling epigenetic alterations in disease
    • [doi:10.1007/978-1-4419-8216-2-12]
    • Martín-Subero, J.I., Esteller, M., 2011. Profiling epigenetic alterations in disease. Adv. Exp. Med. Biol., 711:162-177. [doi:10.1007/978-1- 4419-8216-2-12]
    • (2011) Adv. Exp. Med. Biol. , Issue.711 , pp. 162-177
    • Martín-Subero, J.I.1    Esteller, M.2
  • 19
    • 77958155198 scopus 로고    scopus 로고
    • Current status and future of liver transplantation
    • [doi:10. 1055/s-0030-1267541
    • Merion, R.M., 2010. Current status and future of liver transplantation. Semin. Liver Dis., 30(4):411-421. [doi:10. 1055/s-0030-1267541.
    • (2010) Semin. Liver Dis. , vol.30 , Issue.4 , pp. 411-421
    • Merion, R.M.1
  • 21
    • 50249150340 scopus 로고    scopus 로고
    • A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice
    • [doi:10.1038/nprot.2008.80]
    • Mitchell, C., Willenbring, H., 2008. A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice. Nat. Protoc., 3(7):1167-1170. [doi:10.1038/nprot.2008.80]
    • (2008) Nat. Protoc. , vol.3 , Issue.7 , pp. 1167-1170
    • Mitchell, C.1    Willenbring, H.2
  • 22
    • 15944406847 scopus 로고    scopus 로고
    • Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'- deoxycytidine, restores expression of silenced RARβ2 in breast cancer cells
    • [doi101158/1535-7163MCT-04-0079
    • Mongan, N.P., Gudas, L.J., 2005. Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'- deoxycytidine, restores expression of silenced RARβ2 in breast cancer cells. Mol. Cancer Ther., 4(3):477-486. [doi:10.1158/1535-7163.MCT-04-0079.
    • (2005) Mol. Cancer Ther. , vol.4 , Issue.3 , pp. 477-486
    • Mongan, N.P.1    Gudas, L.J.2
  • 23
    • 0035045456 scopus 로고    scopus 로고
    • Participation of histones and histone-modifying enzymes in cell functions through alterations in chromatin structure
    • [doi:10.1093/oxfordjournals.jbchem.a002882]
    • Nakayama, T., Takami, Y., 2001. Participation of histones and histone-modifying enzymes in cell functions through alterations in chromatin structure. J. Biochem., 129(4): 491-499. [doi:10.1093/oxfordjournals.jbchem. a002882]
    • (2001) J. Biochem. , vol.129 , Issue.4 , pp. 491-499
    • Nakayama, T.1    Takami, Y.2
  • 24
    • 0035576813 scopus 로고    scopus 로고
    • Transient expression of cyclin D1 is sufficient to promote hepatocyte replication and liver growth in vivo
    • Nelsen, C.J., Rickheim, D.G., Timchenko, N.A., Stanley, M.W., Albrecht, J.H., 2001. Transient expression of cyclin D1 is sufficient to promote hepatocyte replication and liver growth in vivo. Cancer Res., 61(23):8564-8568.
    • (2001) Cancer Res. , vol.61 , Issue.23 , pp. 8564-8568
    • Nelsen, C.J.1    Rickheim, D.G.2    Timchenko, N.A.3    Stanley, M.W.4    Albrecht, J.H.5
  • 25
    • 58249117627 scopus 로고    scopus 로고
    • Role of cyclin D1 as a mediator of c-Met- and β-catenin-induced hepatocarcinogenesis
    • [doi101158/0008-5472CAN-08-2514
    • Patil, M.A., Lee, S.A., Macias, E., Lam, E.T., Xu, C.R., Jones, K.D., Ho, C., Rodriguez-Puebla, M., Chen, X., 2009. Role of cyclin D1 as a mediator of c-Met- and β-catenin-induced hepatocarcinogenesis. Cancer Res., 69(1):253-261. [doi:10.1158/0008-5472.CAN-08-2514.
    • (2009) Cancer Res. , vol.69 , Issue.1 , pp. 253-261
    • Patil, M.A.1    Lee, S.A.2    MacIas, E.3    Lam, E.T.4    Xu, C.R.5    Jones, K.D.6    Ho, C.7    Rodriguez-Puebla, M.8    Chen, X.9
  • 26
    • 0027389019 scopus 로고
    • B-myc inhibits neoplastic transformation and transcriptional activation by c-myc
    • [doi:10.1128/MCB.13.2.1130]
    • Resar, L.M., Dolde, C., Barret, J.F., Dang, C.V., 1993. B-myc inhibits neoplastic transformation and transcriptional activation by c-myc. Mol. Cell. Biol., 13(2):1130-1136. [doi:10.1128/MCB.13.2.1130]
    • (1993) Mol. Cell. Biol. , vol.13 , Issue.2 , pp. 1130-1136
    • Resar, L.M.1    Dolde, C.2    Barret, J.F.3    Dang, C.V.4
  • 27
    • 78650774491 scopus 로고    scopus 로고
    • New concepts in liver regeneration
    • [doi:10.1111/j.1440-1746.2010.06539.x]
    • Riehle, K.J., Dan, Y.Y., Campbell, J.S., Fausto, N., 2011. New concepts in liver regeneration. J. Gastroenterol. Hepatol., 26(7):1218. [doi:10.1111/j.1440-1746.2010.06539.x]
    • (2011) J. Gastroenterol. Hepatol. , vol.26 , Issue.7 , pp. 1218
    • Riehle, K.J.1    Dan, Y.Y.2    Campbell, J.S.3    Fausto, N.4
  • 29
    • 0033551388 scopus 로고    scopus 로고
    • New myc-interacting proteins: A second myc network emerges
    • [doi:10.1038/sj.onc.1202725]
    • Sakamuro, D., Prendergast, G., 1999. New myc-interacting proteins: A second myc network emerges. Oncogene, 18(19):2942-2954. [doi:10.1038/sj.onc. 1202725]
    • (1999) Oncogene , vol.18 , Issue.19 , pp. 2942-2954
    • Sakamuro, D.1    Prendergast, G.2
  • 30
    • 69249230769 scopus 로고    scopus 로고
    • Mammalian cell-cycle regulation: Several Cdks, numerous cyclins and diverse compensatory mechanisms
    • [doi:10.1038/onc.2009.170]
    • Satyanarayana, A., Kaldis, P., 2009. Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene, 28(33):2925-2939. [doi:10.1038/onc.2009.170]
    • (2009) Oncogene , vol.28 , Issue.33 , pp. 2925-2939
    • Satyanarayana, A.1    Kaldis, P.2
  • 31
    • 50249167673 scopus 로고    scopus 로고
    • Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
    • [doi:10.1038/nn.2172]
    • Shen, S., Sandoval, J., Swiss, V.A., Li, J., Dupree, J., Franklin, R.J.M., Casaccia-Bonnefil, P., 2008. Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat. Neurosci., 11(9): 1024-1034. [doi:10.1038/nn.2172]
    • (2008) Nat. Neurosci. , vol.11 , Issue.9 , pp. 1024-1034
    • Shen, S.1    Sandoval, J.2    Swiss, V.A.3    Li, J.4    Dupree, J.5    Franklin, R.J.M.6    Casaccia-Bonnefil, P.7
  • 32
    • 0029071657 scopus 로고
    • D-type cyclins
    • [doi101016/S0968-0004(00) 89005-89012
    • Sherr, C.J., 1995. D-type cyclins. Trends Biochem. Sci., 20(5):187-190. [doi:10.1016/S0968-0004(00)89005-2.
    • (1995) Trends Biochem. Sci. , vol.20 , Issue.5 , pp. 187-190
    • Sherr, C.J.1
  • 33
    • 0034660892 scopus 로고    scopus 로고
    • The Pezcoller lecture: Cancer cell cycles revisited
    • Sherr, C.J., 2000. The Pezcoller lecture: cancer cell cycles revisited. Cancer Res., 60(14):3689-3695.
    • (2000) Cancer Res. , vol.60 , Issue.14 , pp. 3689-3695
    • Sherr, C.J.1
  • 34
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • [doi:10.1101/gad.13.12.1501]
    • Sherr, C.J., Roberts, J.M., 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev., 13(12):1501-1512. [doi:10.1101/gad.13.12.1501]
    • (1999) Genes Dev. , vol.13 , Issue.12 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 35
    • 12144291647 scopus 로고    scopus 로고
    • Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells
    • [doi:10.1093/carcin/bgh014]
    • Simile, M.M., de Miglio, M.R., Muroni, M.R., Frau, M., Asara, G., Serra, S., Muntoni, M.D., Seddaiu, M.A., Daino, L., Feo, F., et al., 2004. Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells. Carcinogenesis, 25(3): 333-341. [doi:10.1093/carcin/bgh014]
    • (2004) Carcinogenesis , vol.25 , Issue.3 , pp. 333-341
    • Simile, M.M.1    De Miglio, M.R.2    Muroni, M.R.3    Frau, M.4    Asara, G.5    Serra, S.6    Muntoni, M.D.7    Seddaiu, M.A.8    Daino, L.9    Feo, F.10
  • 36
    • 1042267223 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells
    • [doi101158/1078-0432CCR-03-0100
    • Takai, N., Desmond, J.C., Kumagai, T., Gui, D., Said, J.W., Whittaker, S., Miyakawa, I., Koeffler, H.P., 2004. Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells. Clin. Cancer Res., 10(3):1141-1149. [doi:10.1158/1078-0432.CCR-03-0100.
    • (2004) Clin. Cancer Res. , vol.10 , Issue.3 , pp. 1141-1149
    • Takai, N.1    Desmond, J.C.2    Kumagai, T.3    Gui, D.4    Said, J.W.5    Whittaker, S.6    Miyakawa, I.7    Koeffler, H.P.8
  • 37
    • 0344407016 scopus 로고    scopus 로고
    • Histone deacetylases: Unique players in shaping the epigenetic histone code
    • [doi:10.1111/j.1749-6632.2003.tb05964.x]
    • Thiaqalinqam, S., Cheng, K.H., Lee, H.J., Mineva, N., Thiaqalingam, A., Ponte, J.F., 2003. Histone deacetylases: unique players in shaping the epigenetic histone code. Ann. N. Y. Acad. Sci., 983(1):84-100. [doi:10.1111/j.1749-6632.2003.tb05964.x]
    • (2003) Ann. N. Y. Acad. Sci. , vol.983 , Issue.1 , pp. 84-100
    • Thiaqalinqam, S.1    Cheng, K.H.2    Lee, H.J.3    Mineva, N.4    Thiaqalingam, A.5    Ponte, J.F.6
  • 38
    • 0033848849 scopus 로고    scopus 로고
    • Histone acetylation and epigenetic code
    • [doi101002/1521-1878(200 009229<836AID-BIES9>30CO2-O]
    • Turner, B.M., 2000. Histone acetylation and epigenetic code. Bioessays, 22(9):836-845. [doi:10.1002/1521-1878(200 009)22:9<836::AID-BIES9>3.0. CO;2-O]
    • (2000) Bioessays , vol.22 , Issue.9 , pp. 836-845
    • Turner, B.M.1
  • 39
    • 54449086844 scopus 로고    scopus 로고
    • HDAC1 cooperates with C/EBPα in the inhibition of liver proliferation in old mice
    • [doi:10.1074/jbc.M803544200]
    • Wang, G.L., Salisbury, E., Shi, X.R., Timchenko, L., Medrano, E.E., Timchenko, N.A., 2008a. HDAC1 cooperates with C/EBPα in the inhibition of liver proliferation in old mice. J. Biol. Chem., 283(38):26169-26178. [doi:10.1074/jbc. M803544200]
    • (2008) J. Biol. Chem. , vol.283 , Issue.38 , pp. 26169-26178
    • Wang, G.L.1    Salisbury, E.2    Shi, X.R.3    Timchenko, L.4    Medrano, E.E.5    Timchenko, N.A.6
  • 40
    • 54449099274 scopus 로고    scopus 로고
    • HDAC1 promotes liver proliferation in young mice via interactions with C/EBPβ
    • [doi:10.1074/jbc.M803545200]
    • Wang, G.L., Salisbury, E., Shi, X.R., Timchenko, L., Medrano, E.E., Timchenko, N.A., 2008b. HDAC1 promotes liver proliferation in young mice via interactions with C/EBPβ. J. Biol. Chem., 283(38):26179-26187. [doi:10.1074/jbc. M803545200]
    • (2008) J. Biol. Chem. , vol.283 , Issue.38 , pp. 26179-26187
    • Wang, G.L.1    Salisbury, E.2    Shi, X.R.3    Timchenko, L.4    Medrano, E.E.5    Timchenko, N.A.6
  • 41
    • 4344624078 scopus 로고    scopus 로고
    • Regulation of liver regeneration
    • [doi:10.1093/ndt/gfh1034]
    • Zimmermann, A., 2004. Regulation of liver regeneration. Nephrol. Dial. Transplant., 19(Suppl. 4):iv6-iv10. [doi:10.1093/ndt/gfh1034]
    • (2004) Nephrol. Dial. Transplant. , vol.19 , Issue.SUPPL. 4
    • Zimmermann, A.1


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