Low vitamin D levels, prediabetes and prehypertension in healthy African American adults

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 22, Issue 10, 2012, Pages 877-882

  Gupta, A K ^a   Brashear, M M ^a   Johnson, W D ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

CVD risk; Fasting blood sugar; Preclinical; Preventive medicine; Resting blood pressure

Indexed keywords

VITAMIN D;

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; BLOOD; BLOOD PRESSURE; CAUCASIAN; COMORBIDITY; CROSS-SECTIONAL STUDY; DIET SUPPLEMENTATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; MALE; MIDDLE AGED; NUTRITION; PATHOPHYSIOLOGY; PREHYPERTENSION; PREVALENCE; RISK FACTOR; STATISTICAL MODEL; VITAMIN D DEFICIENCY;

ADULT; AFRICAN AMERICANS; AGED; BLOOD GLUCOSE; BLOOD PRESSURE; COMORBIDITY; CROSS-SECTIONAL STUDIES; DIETARY SUPPLEMENTS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NUTRITION SURVEYS; PREDIABETIC STATE; PREHYPERTENSION; PREVALENCE; RISK FACTORS; VITAMIN D; VITAMIN D DEFICIENCY; YOUNG ADULT;

EID: 84866021042     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2012.01.006     Document Type: Article

References (21)

1. Florentin M., Elisaf M.S., Mikhailidis D.P., Liberopoulos E.N. Vitamin D and metabolic syndrome: is there a link?. Curr Pharm Des 2010, 16(30):3417-3434. [Review].
2. Boucher B.J. Vitamin D insufficiency and diabetes risks. Curr Drug Targets 2010, 12(1):61-87. [Review].
3. Pilz S., Tomaschitz A., Ritz E., Pieber T.R. Vitamin D status and arterial hypertension: a systematic review. Nat Rev Cardiol 2009, 6(10):621-630. [Review].
4. Forman J.P., Williams J.S., Fisher N.D. Plasma 25-hydroxyvitamin D and regulation of the renin-angiotensin system in humans. Hypertension 2010, 55(5):1283-1288.
5. Dobnig H., Pilz S., Scharnagl H., Renner W., Seelhorst U., Wellnitz B., et al. Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality. Arch Intern Med 2008, 168(12):1340-1349.
6. Gupta A.K., Brashear M.M., Johnson W.D. Prediabetes and prehypertension in healthy adults are associated with low vitamin D levels. Diabetes Care 2011, 34(3):658-660. [Epub 2011 Jan 31].
7. Grant W.B., Peiris A.N. Possible role of serum 25-hydroxyvitamin D in black-white health disparities in the United States. J Am Med Dir Assoc 2010, 11(9):617-628.
8. Fiscella K., Franks P. Vitamin D, race, and cardiovascular mortality: findings from a national US sample. Ann Fam Med 2010, 8(1):11-18.
9. Melamed M.L., Astor B., Michos E.D., Hostetter T.H., Powe N.R., Muntner P. 25-Hydroxyvitamin D levels, race, and the progression of kidney disease. J Am Soc Nephrol 2009, 20(12):2631-2639. [Epub 2009 Oct 29].
10. Bodnar L.M., Simhan H.N. Vitamin D may be a link to black-white disparities in adverse birth outcomes. Obstet Gynecol Surv 2010, 65(4):273-284.
11. Reis J.P., Michos E.D., von Mühlen D., Miller E.R. Differences in vitamin D status as a possible contributor to the racial disparity in peripheral arterial disease. Am J Clin Nutr 2008, 88(6):1469-1477.
12. Wright N.C., Chen L., Niu J., Neogi T., Javiad K., Nevitt M.A., et al. Defining physiologically "normal" vitamin D in African Americans. Osteoporos Int 2011 Dec 22, [Epub ahead of print].
13. United States Department of Health and Human Services. The national health and nutrition examination survey, [accessed August 2009]. http://www.cdc.gov/nchs/nhanes.htm.
14. Centers for Disease Control and Prevention NHANES 2005-2006 public data general release file documentation Available from:, [accessed 29.06.11]. http://www.cdc.gov/nchs/data/nhanes/nhanes_05_06/general_data_release_doc_05_06.pdf.
15. Yetley E.A., Pfeiffer C.M., Schleicher R.L., Phinney K.W., Lacher D.A., Christakos S., et al. Vitamin D roundtable on the NHANES monitoring of serum 25(OH)D: assay challenges and options for resolving them. NHANES monitoring of serum 25-hydroxyvitamin D: a roundtable summary. J Nutr 2010, 140:2030S-2045S.
16. National Center for Health Statistics Revised analytical note for NHANES 2000-2006 and NHANES III (1988-1994) 25-hydroxyvitamin D analysis (revised November 2010) Available from:, [accessed 29.06.11]. http://www.cdc.gov/nchs/data/nhanes/nhanes3/VitaminD_analyticnote.pdf.
17. Gupta A.K., Johnson W.D. Prediabetes and prehypertension in disease free obese adults correlate with an exacerbated systemic proinflammatory milieu. J Inflamm 2010 Jul 26, 7:36.
18. Gupta A.K., McGlone M.M., Greenway F.L., Johnson W.D. Prehypertension in disease-free adults: a marker for an adverse cardiometabolic risk profile. Hypertens Res 2010, 33(9):905-910. [Epub 2010 Jun 10].
19. Gupta A.K., McGlone M.M., Johnson W.D. Apparently healthy U.S. adults with coexisting prehypertension and prediabetes are on a pathway with potential for early cardiovascular events. Hypertens Res 2011, 34(4):456-461. [Epub 2011 Jan 13].
20. Pillai D.K., Iqbal S.F., Benton A.S., Lerner J., Wiles A., Foerster M., et al. Associations between genetic variants in vitamin d metabolism and asthma characteristics in young African Americans: a pilot study. J Investig Med 2011, 59(6):938-946.
21. Fiscella K., Winters P., Tancredi D., Franks P. Racial disparity in blood pressure: is vitamin D a factor?. J Gen Intern Med 2011, 26(10):1105-1111.