Coexisting prehypertension and prediabetes in healthy adults: A pathway for accelerated cardiovascular events

Hypertension Research

Volumn 34, Issue 4, 2011, Pages 456-461

  Gupta, Alok K ^a   Brashear, Meghan M ^a   Johnson, William D ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

blood pressure; central adiposity; fasting serum glucose; insulin resistance; systemic inflammation

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; COMORBIDITY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DIET RESTRICTION; FEMALE; GLUCOSE BLOOD LEVEL; GROUPS BY AGE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INFLAMMATION; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; OBESITY; PREHYPERTENSION; PREVALENCE; RACE DIFFERENCE; RISK FACTOR; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; UNITED STATES; WAIST CIRCUMFERENCE;

ADIPOSITY; ADULT; AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; COMORBIDITY; FEMALE; HUMANS; INSULIN RESISTANCE; LIPIDS; MALE; MIDDLE AGED; NUTRITION SURVEYS; PREDIABETIC STATE; PREHYPERTENSION; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; UNITED STATES;

EID: 79953726750     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2010.267     Document Type: Article

References (25)

1. Lee DE, Cooper RS. Recommendations for global hypertension monitoring and prevention. Curr Hypertens Rep 2009; 11: 444-449.
2. Juutilainen A, Lehto S, Ronnemaa T, Pyorala K, Laakso M. Type 2 diabetes as a "coronary heart disease equivalent": an 18-year prospective population-based study in Finnish subjects. Diabetes Care 2005; 28: 2901-2907. (Pubitemid 43942922)
3. Whiteley L, Padmanabhan S, Hole D, Isles C. Should diabetes be considered a coronary heart disease risk equivalent?: results from 25 years of follow-up in the Renfrew and Paisley survey. Diabetes Care 2005; 28: 1588-1593. (Pubitemid 40923069)
4. Vasan RS, Larson MG, Leip EP, Kannel WB, Levy D. Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study. Lancet 2001; 358: 1682-1686. (Pubitemid 33124327)
5. De Marco M, de Simone G, Roman MJ, Chinali M, Lee ET, Russell M, Howard BV, Devereux RB. Cardiovascular and metabolic predictors of progression of prehypertension into hypertension. The Strong Heart Study. Hypertension 2009; 54: 974-980.
6. Edelstein SL, Knowler WC, Bain RP, Andres R, Barrett-Connor EL, Dowse GK. Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies. Diabetes 1997; 46: 701-710. (Pubitemid 27143390)
7. Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001; 344: 1343-1350. (Pubitemid 32378388)
8. Buchanan TA, Xiang AH, Peters RK, Kjos SL, Marroquin A, Goico J. Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk Hispanic women. Diabetes 2002; 51: 2796-2803. (Pubitemid 34970933)
9. Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393-403.
10. 00 phenotype to earlier manifestations of coronary artery disease in patients with glucose intolerance and type 2 diabetes mellitus. Am J Cardiol 2007; 99: 369-373. (Pubitemid 46157216)
11. Castelli WP, Doyle JT, Gordon T, Hames CG, Hjortland MC, Hulley SB. HDL cholesterol and other lipids in coronary heart disease. Circulation 1977; 55: 767-772.
12. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Prospective studies collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903-1913. (Pubitemid 35472129)
13. Nielson C, Lange T, Hadjokas N. Blood glucose and coronary artery disease in nondiabetic patients. Diabetes Care 2006; 29: 998-1001. (Pubitemid 44115234)
14. Saito I, Iso H, Kokubo Y, Inoue M, Tsugane S. Metabolic syndrome and all-cause and cardiovascular disease mortality: Japan Public Health Center-based Prospective (JPHC) Study. Circ J 2009; 73: 878-884.
15. Gupta A K, McGlone M, Greenway FL, Johnson WD. Prehypertension in diseasfree adults: a marker for an adverse cardiometabolic risk profile. Hypertension Research. Hypertens Res 2010; 33: 905-910.
16. United States Department of Health and Human Services. The National Health and Nutrition Examination Survey. http://www.cdc.gov/nchs/nhanes.htm. Accessed. August 2009.
17. Jensen M D. Role of Body Fat Distribution and the Metabolic Complications of Obesity. J Clin Endocrinol Metab 2008; 93: S57-S63.
18. Blüher M. Adipose tissue dysfunction in obesity. Exp Clin Endocrinol Diabetes 2009; 117: 241-250.
19. Bakhai A. Adipokines-targeting a root cause of cardiometabolic risk. QJM 2008; 101: 767-776.
20. Gupta AK, Johnson WD. Prediabetes and prehypertension in disease-free obese adults correlate with an exacerbated systemic proinflammatory milieu. J Inflamm (Lond) 2010; 7: 36.
21. Barr EL, Cameron AJ, Balkau B, Zimmet PZ, Welborn TA, Tonkin AM. HOMA insulin sensitivity index and the risk of all-cause mortality and cardiovascular disease events in the general population: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab) study. Diabetologia 2010; 53: 79-88.
22. Tamada M, Makita S, Abiko A, Naganuma Y, Nagai M, Nakamura M. Low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio as a useful marker for early-stage carotid atherosclerosis. Metabolism 2010; 59: 653-657.
23. Toth PP. Reverse cholesterol transport: high-density lipoprotein's magnificent mile. Curr Atheroscler Rep 2003; 5: 386-393 (Review). (Pubitemid 38898898)
24. Gupta AK, Ross EA, Myers JN, Kashyap ML. Increased reverse cholesterol transport in athletes. Metabolism 1993; 42: 684-690. (Pubitemid 23173405)
25. Malone DC, Boudreau DM, Nichols GA, Raebel MA, Fishman PA, Feldstein AC. Association of Cardiometabolic Risk Factors and Prevalent Cardiovascular Events. Metab Syndr Relat Disord 2009; 7: 585-593.