New mixed-mode adsorbent and its application for separation of bovine colostrum immunoglobulin

Huagong Xuebao/CIESC Journal

Volumn 63, Issue 8, 2012, Pages 2453-2459

  Chen, Zhenming ^a   Lin, Dongqiang ^a   Yao, Shanjing ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

2 mercaptoimidazole; Bovine colostrums; Divinylsulfone activation; Immunoglobulin; Mixed mode chromatography

Indexed keywords

2-MERCAPTOIMIDAZOLE; ADSORPTION BEHAVIOR; ADSORPTION CHROMATOGRAPHY; AGAROSE BEADS; BOVINE COLOSTRUMS; CHROMATOGRAPHIC CONDITIONS; FUNCTIONAL LIGANDS; HIGH CAPACITY; IMMUNOGLOBULIN; LIGAND COUPLING; LIGAND DENSITY; MIXED MODE; MIXED-MODE CHROMATOGRAPHY; PH ADJUSTMENT; PRODUCT PURITY; THIOPHILIC;

ADSORPTION; CHROMATOGRAPHY; LIGANDS; OPTIMIZATION; SEPARATION;

MAMMALS;

EID: 84866020609     PISSN: 04381157     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.0438-1157.2012.08.017     Document Type: Article

References (17)

1. Yao Shanjing, Gao Dong, Lin Dongqiang. Novel technology in bioseparation process-mixed-mode chromatography [J]. Journal of Chemical Industry and Engineering(China), 2007, 58(9): 2169-2177
2. Ghose S, Hubbard B, Cramer S M. Protein interactions in hydrophobic charge induction chromatography(HCIC) [J]. Biotechnology Progress, 2005, 21(2): 498-508
3. Burton S C, Harding D R K. Hydrophobic charge induction chromatography: salt independent protein adsorption and facile elution with aqueous buffers [J]. Journal of Chromatography A, 1998, 814: 71-81
4. Guerrier L, Girot P, Schwartz W, Boschetti E. New method for the selective capture of antibodies under physiological conditions [J]. Bioseparation, 2000, 9(4): 211-221
5. Mowry M C, Meagher M, Smith L, Marks J, Subramanian A. Production and purification of a chimeric monoclonal antibody against botulinum neurotoxin serotype A [J]. Protein Expression and Purification, 2004, 37(2): 399-408
6. Xia H F, Lin D Q, Wang L P, Chen Z J, Yao S J. Preparation and evaluation of cellulose adsorbents for hydrophobic charge induction chromatography [J]. Industrial & Engineering Chemistry Research, 2008, 47(23): 9566-9572
7. Xia H F, Lin D Q, Chen Z M, Yao S J. Influences of ligand structure and pH on the adsorption with hydrophobic charge induction adsorbents: a case study of antibody IgY [J]. Separation Science and Technology, 2011, 46(12): 1957-1965
8. Zhuang Tiantian, Xia Haifeng, Lin Dongqiang, Yao Shanjing. Separation of immunoglobulin from porcine plasma with mixed-mode adsorption chromatography [J]. CIESC Journal, 2010, 61(2): 336-341
9. Tong Hongfei, Lin Dongqiang, Yao Shanjing. Purification of immunoglobulin IgY with hydrophobic charge induction chromatography [J]. CIESC Journal, 2011, 62(6): 1574-1580
10. Tong H F, Lin D Q, Pan Y, Yao S J. A new purification process for goose immunoglobulin IgY(Δ Fc)with hydrophobic charge-induction chromatography [J]. Biochemical Engineering Journal, 2011, 56(3): 205-211
11. Pakkanen R, Aalto J. Growth factors and antimicrobial factors of bovine colostrum [J]. International Dairy Journal, 1997, 7(5): 285-291
12. Gao Lixia, Guo Aiping, Luo Yazhou. The active substances and the development of bovine colostrum [J]. Academic Periodical of Farm Products Processing, 2010, 4: 45-47
13. Cao Jinsong, Wang Xiaoqin. The development and prospect of bovine colostrums-based products [J]. Food Science, 1999, 5: 14-17
14. Zhong Kai. The study on preparing immunoglobulin G from bovine colostrums by ultrafiltration [D]. Zhengzhou: Henan Agricultural University, 2002: 18-20
15. Xu Y, Sleigh R, Hourigan J, Johnson R. Separation of bovine immunoglobulin G and glycomacropeptide from dairy whey [J]. Process Biochemistry, 2000, 36(5): 393-399
16. Alwan S, Mashikhi A L, Nakai S. Isolation of bovine immunoglobulins and lactoferrin from whey proteins by gel filtration techniques [J]. Journal of Dairy Science, 1987, 70(12): 2486-2492
17. Boschetti E. The use of thiophilic chromatography for antibody purification: a review [J]. Journal of Biochemical and Biophysical Methods, 2001, 49: 361-389