Transdermal delivery of the anti-rheumatic agent methotrexate using a solid-in-oil nanocarrier

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 1, 2012, Pages 158-163

  Yang, Fan ^a   Kamiya, Noriho ^a   Goto, Masahiro ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Methotrexate; Solid in oil (S O) nanotechnique; Sugar ester; Surfactant complex; Transdermal drug delivery system (TDDS)

Indexed keywords

METHOTREXATE; NANOCARRIER; SOLID IN OIL NANOCARRIER; UNCLASSIFIED DRUG; UREA;

ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG PENETRATION; DRUG RELEASE; DRUG STABILITY; FEMALE; NONHUMAN; PARTICLE SIZE; SKIN PENETRATION; STRATUM CORNEUM; SWINE; TRANSDERMAL DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; AMINO ACIDS; ANIMALS; ANTIRHEUMATIC AGENTS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FEMALE; METHOTREXATE; MYRISTATES; NANOSTRUCTURES; PARTICLE SIZE; PERMEABILITY; SKIN ABSORPTION; SOLVENTS; SURFACE-ACTIVE AGENTS; SWINE; SWINE, MINIATURE; UREA;

EID: 84866008222     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.05.016     Document Type: Article

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