A column-switching liquid chromatography-tandem mass spectrometry method for quantitation of 2-cyanoethylmercapturic acid and 2-hydroxyethylmercapturic acid in Chinese smokers

Analytical Biochemistry

Volumn 430, Issue 1, 2012, Pages 75-82

  Hou, Hongwei ^a   Xiong, Wei ^a   Gao, Na ^b   Zhang, Xiaotao ^a   Tang, Gangling ^a   Hu, Qingyuan ^a  

^a ZHENGZHOU TOBACCO RESEARCH INSTITUTE OF CNTC   (China)

^b ZHENGZHOU UNIVERSITY   (China)

Author keywords

2 Hydroxyethylmercapturic acid; 2 Cyanoethylmercapturic acid; Column switching; LC MS MS; Urine

Indexed keywords

COLUMN CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; TOBACCO;

COLUMN SWITCHING; DOSE RESPONSE RELATIONSHIPS; LC-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; METABOLITE CONCENTRATIONS; RELATIVE STANDARD DEVIATIONS; RESTRICTED ACCESS MATERIALS; URINE;

SMOKE;

2 CYANOETHYLMERCAPTURIC ACID; 2 HYDROXYETHYLACETYLCYSTEINE; ACETYLCYSTEINE DERIVATIVE; ACRYLONITRILE; BIOLOGICAL MARKER; COTININE; UNCLASSIFIED DRUG;

ACCURACY; ADULT; ARTICLE; CHINESE; COLUMN SWITCHING LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HUMAN; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SMOKING; TANDEM MASS SPECTROMETRY; URINALYSIS; URINARY EXCRETION;

EID: 84866000271     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.07.026     Document Type: Article

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