Infrared pupillometry to detect the light reflex during cardiopulmonary resuscitation: A case series

Resuscitation

Volumn 83, Issue 10, 2012, Pages 1223-1228

  Behrends, Matthias ^a   Niemann, Claus U ^a   Larson, Merlin D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cardiopulmonary resuscitation; Outcome; Pupillary light reflex; Pupillometry

Indexed keywords

ADULT; AGED; ALARM MONITORING; ARTICLE; CASE STUDY; COLLAPSE; DETERIORATION; ENDOTRACHEAL INTUBATION; FEMALE; HEART ARREST; HEART ARRHYTHMIA; HUMAN; INFRARED PUPILLOMETRY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PARALYSIS; PRIORITY JOURNAL; PROGNOSIS; PULSE PRESSURE; PUPIL REFLEX; PUPILLOMETER; PUPILLOMETRY; QUALITY CONTROL; RELIABILITY; RESUSCITATION; RETURN OF SPONTANEOUS CIRCULATION; SINUS RHYTHM; SURVIVAL; UNCONSCIOUSNESS;

ADULT; AGED; AGED, 80 AND OVER; CARDIOPULMONARY RESUSCITATION; FEMALE; HUMANS; INFRARED RAYS; LIGHT; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; REFLEX, PUPILLARY; YOUNG ADULT;

EID: 84865865290     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2012.05.013     Document Type: Article

References (35)

1. Gazmuri R.J., Nadkarni V.M., Nolan J.P., et al. Scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care identified during the 2005 International Consensus Conference on ECC [corrected] and CPR science with treatment recommendations: a consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian Resuscitation Council, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, and the New Zealand Resuscitation Council); the American Heart Association Emergency Cardiovascular Care Committee; the Stroke Council; and the Cardiovascular Nursing Council. Circulation 2007, 116:2501-2512.
2. Levine R.L., Wayne M.A., Miller C.C. End-tidal carbon dioxide and outcome of out-of-hospital cardiac arrest. N Engl J Med 1997, 337:301-306.
3. Fatovich D.M., Jacobs I.G., Celenza A., Paech M.J. An observational study of bispectral index monitoring for out of hospital cardiac arrest. Resuscitation 2006, 69:207-212.
4. Azim N., Wang C.Y. The use of bispectral index during a cardiopulmonary arrest: a potential predictor of cerebral perfusion. Anaesthesia 2004, 59:610-612.
5. Steen-Hansen J.E., Hansen N.N., Vaagenes P., Schreiner B. Pupil size and light reactivity during cardiopulmonary resuscitation: a clinical study. Crit Care Med 1988, 16:69-70.
6. Larson M.D., Muhiudeen I. Pupillometric analysis of the 'absent light reflex'. Arch Neurol 1995, 52:369-372.
7. Zhao D., Weil M.H., Tang W., et al. Pupil diameter and light reaction during cardiac arrest and resuscitation. Crit Care Med 2001, 29:825-828.
8. Levy D.E., Caronna J.J., Singer B.H., et al. Predicting outcome from hypoxic-ischemic coma. JAMA 1985, 253:1420-1426.
9. van Hoeyweghen R.M.A., Bossaert L. Decision making to cease or to continue cardiopulmonary resuscitation. Resuscitation 1989, 17S:S137-S147.
10. Longstreth W.T., Diehr P., Inui T.S., Jorgensen E.O., Malchow-Moller A.M. Prediction of awakening after out-of-hospital cardiac arrest cerebral prognostic signs during cardiopulmonary resuscitation. N Engl J Med 1983, 308:1378-1382.
11. Condemi A., Donatiello G., Mauro M., et al. Importance of pupillary and photomotor reflexes in cardiac resuscitation. Minerva Anestesiol 1981, 47:885-890.
12. Du R., Meeker M., Bacchetti P., et al. Evaluation of the portable infrared pupillometer. Neurosurgery 2005, 57:198-203. discussion 198-203.
13. Meeker M., Du R., Bacchetti P., et al. Pupil examination: validity and clinical utility of an automated pupillometer. J Neurosci Nurs 2005, 37:34-40.
14. Larson M.D.M.I. Pupillometric analysis of the "absent light reflex" Arch Neurol 1995, 52:369-372.
15. Okada K., Ohde S., Otani N., et al. Prediction protocol for neurological outcome for survivors of out-of-hospital cardiac arrest treated with targeted temperature management. Resuscitation 2012, 83:734-739.
16. Peberdy M.A., Kaye W., Ornato J.P., et al. Cardiopulmonary resuscitation of adults in the hospital: a report of 14720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation. Resuscitation 2003, 58:297-308.
17. Siesjo B.K. Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. (1992). J Neurosurg 2008, 108:616-631.
18. 2+] in hypoxia and ischemia in rat brain in vivo. J Gen Physiol 1990, 95:837-866.
19. Heuser D., Guggenberger H. Ionic changes in brain ischaemia and alterations produced by drugs. Br J Anaesth 1985, 57:23-33.
20. Mehta C.R., H J.F. Exact power of conditional and unconditional tests: going beyond the 2×2 contingency table. Am Stat 1993, 47:91-98.
21. Trujillo-Ortiz A, Hernandez-Walls A, Castro-Perez L, et al. Barnardexactest: Barnard's Exact Probability Test. A MATLAB file. A MATLAB file; 2004. http://www.mathworks.com/mathlabcentral/fileexchange/loadFile.
22. Yang L.L., Niemann C.U., Larson M.D. Mechanism of pupillary reflex dilation in awake volunteers and in organ donors. Anesthesiology 2003, 99:1281-1286.
23. Whytt R. An essay on the vital and other involuntary motions of animals 1751, T Beckert, Auld and Smellie, Edinburgh.
24. Jorgensen E.O., Malchow-Moller A.M. Cerebral prognostic signs during cardiopulmonary resuscitation. Resuscitation 1978, 6:217-225.
25. Jorgensen E.O. Course of neurological recovery and cerebral prognostic signs during cardio-pulmonary resuscitation. Resuscitation 1997, 35:9-16.
26. Loewenfeld I.E. The pupil: anatomy, physiology and clinical applications 1993, Wayne State University Press, Detroit.
27. Gamlin P.D., McDougal D.H., Pokorny J., et al. Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells. Vision Res 2007, 47:946-954.
28. Kardon R., Anderson S.C., Damarjian T.G., et al. Chromatic pupil responses: preferential activation of the melanopsin-mediated versus outer photoreceptor-mediated pupil light reflex. Ophthalmology 2009, 116:1564-1573.
29. Park J.C., Moura A.L., Raza A.S., et al. Toward a clinical protocol for assessing rod, cone, and melanopsin contributions to the human pupil response. Invest Ophthalmol Vis Sci 2011, 52:6624-6635.
30. Xue T., Do M.T.H., Riccio A., et al. Melanopsin signalling in mammalian iris and retina. Nature 2011, 479:67-73.
31. Bender M., Weinstein E. Actions of adrenaline and acetylcholine on the denervated iris of the cat and monkey. Am J Physiol 1940, 130:268-275.
32. Gray A.T., Krejci S.T., Larson M.D. Neuromuscular blocking drugs do not alter the pupillary light reflex of anesthetized humans. Arch Neurol 1997, 54:579-584.
33. Neumar R.W., Otto C.W., Link M.S., et al. Part 8: adult advanced cardiovascular life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2010, 122:S729-S767.
34. Goetting M.G., Contreras E. Systemic atropine administration during cardiac arrest does not cause fixed and dilated pupils. Ann Emerg Med 1991, 20:55-57.
35. Bremner F.D., Smith S.E. Bilateral tonic pupils: Holmes Adie syndrome or generalised neuropathy?. Br J Ophthalmol 2007, 91:1620-1623.