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Volumn 107, Issue 6, 2012, Pages 956-960

Predictive value of HER2 serum levels in patients treated with lapatinib or trastuzumab-a translational project in the neoadjuvant GeparQuinto trial

(21)  Witzel, I a   Loibl, S b   Von Minckwitz, G b   Eidtmann, H c   Fehm, T d   Khandan, F e   Schmatloch, S f   Hauschild, M g   Bischoff, J h   Fasching, P A i   Mau, C j   Schem, C c   Rack, B k   Meinhold Heerlein, I l   Liedtke, C m   Karn, T n   Huober, J o   Zu Eulenburg, C a   Issa Nummer, Y b   Untch, M j   more..


Author keywords

breast cancer; HER2; lapatinib; neoadjuvant therapy; serum; trastuzumab

Indexed keywords

CYCLOPHOSPHAMIDE; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; LAPATINIB; TRASTUZUMAB;

EID: 84865864129     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.353     Document Type: Article
Times cited : (29)

References (27)
  • 2
    • 0034808379 scopus 로고    scopus 로고
    • Is circulating HER-2 more than just a tumor marker?
    • Baselga J (2001) Is circulating HER-2 more than just a tumor marker? Clin Cancer Res 7: 2605-2607
    • (2001) Clin Cancer Res , vol.7 , pp. 2605-2607
    • Baselga, J.1
  • 5
    • 0033559210 scopus 로고    scopus 로고
    • Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells
    • Codony-Servat J, Albanell J, Lopez-Talavera JC, Arribas J, Baselga J (1999) Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells. Cancer Res 59: 1196-1201
    • (1999) Cancer Res , vol.59 , pp. 1196-1201
    • Codony-Servat, J.1    Albanell, J.2    Lopez-Talavera, J.C.3    Arribas, J.4    Baselga, J.5
  • 7
    • 73949125361 scopus 로고    scopus 로고
    • Prognostic and predictive value of HER2 extracellular domain in metastatic breast cancer treated with lapatinib and paclitaxel in a randomized phase III study
    • Finn RS, Gagnon R, Di Leo A, Press MF, Arbushites M, Koehler M (2009) Prognostic and predictive value of HER2 extracellular domain in metastatic breast cancer treated with lapatinib and paclitaxel in a randomized phase III study. J Clin Oncol 27: 5552-5558
    • (2009) J Clin Oncol , vol.27 , pp. 5552-5558
    • Finn, R.S.1    Gagnon, R.2    Di Leo, A.3    Press, M.F.4    Arbushites, M.5    Koehler, M.6
  • 9
    • 33750313576 scopus 로고    scopus 로고
    • New guidelines for reporting of tumor marker studies in breast cancer research and treatment: REMARK
    • Hayes DF, Ethier S, Lippman ME (2006) New guidelines for reporting of tumor marker studies in breast cancer research and treatment: REMARK. Breast Cancer Res Treat 100: 237-238
    • (2006) Breast Cancer Res Treat , vol.100 , pp. 237-238
    • Hayes, D.F.1    Ethier, S.2    Lippman, M.E.3
  • 10
    • 0141956319 scopus 로고    scopus 로고
    • Her-2/neu-triggered intracellular tyrosine kinase activation: In vivo relevance of ligandindependent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment
    • Hudelist G, Kostler WJ, Attems J, Czerwenka K, Muller R, Manavi M, Steger GG, Kubista E, Zielinski CC, Singer CF (2003) Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligandindependent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment. Br J Cancer 89: 983-991
    • (2003) Br J Cancer , vol.89 , pp. 983-991
    • Hudelist, G.1    Kostler, W.J.2    Attems, J.3    Czerwenka, K.4    Muller, R.5    Manavi, M.6    Steger, G.G.7    Kubista, E.8    Zielinski, C.C.9    Singer, C.F.10
  • 13
    • 80054817785 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor 2 (HER2) extracellular domain levels are associated with progression-free survival in patients with HER2-positive metastatic breast cancer receiving lapatinib monotherapy
    • Lipton A, Leitzel K, Ali SM, Carney W, Platek G, Steplewski K, Westlund R, Gagnon R, Martin AM, Maltzman J (2011) Human epidermal growth factor receptor 2 (HER2) extracellular domain levels are associated with progression-free survival in patients with HER2-positive metastatic breast cancer receiving lapatinib monotherapy. Cancer 117: 5013-5020
    • (2011) Cancer , vol.117 , pp. 5013-5020
    • Lipton, A.1    Leitzel, K.2    Ali, S.M.3    Carney, W.4    Platek, G.5    Steplewski, K.6    Westlund, R.7    Gagnon, R.8    Martin, A.M.9    Maltzman, J.10
  • 14
    • 78650492709 scopus 로고    scopus 로고
    • Lapatinib for breast cancer: A review of the current literature
    • MacFarlane RJ, Gelmon KA (2011) Lapatinib for breast cancer: a review of the current literature. Expert Opin Drug Saf 10: 109-121
    • (2011) Expert Opin Drug Saf , vol.10 , pp. 109-121
    • MacFarlane, R.J.1    Gelmon, K.A.2
  • 17
    • 0035874981 scopus 로고    scopus 로고
    • Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells
    • Molina MA, Codony-Servat J, Albanell J, Rojo F, Arribas J, Baselga J (2001) Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res 61: 4744-4749
    • (2001) Cancer Res , vol.61 , pp. 4744-4749
    • Molina, M.A.1    Codony-Servat, J.2    Albanell, J.3    Rojo, F.4    Arribas, J.5    Baselga, J.6
  • 21
    • 84856340091 scopus 로고    scopus 로고
    • HER2 shedding and serum HER2 extracellular domain: Biology and clinical utility in breast cancer
    • Tse C, Gauchez AS, Jacot W, Lamy PJ (2011) HER2 shedding and serum HER2 extracellular domain: biology and clinical utility in breast cancer. Cancer Treat Rev 38: 133-142
    • (2011) Cancer Treat Rev , vol.38 , pp. 133-142
    • Tse, C.1    Gauchez, A.S.2    Jacot, W.3    Lamy, P.J.4
  • 25
    • 78049309932 scopus 로고    scopus 로고
    • Lapatinib, a dual HER1/HER2 tyrosine kinase inhibitor, augments basal cleavage of HER2 extracellular domain (ECD) to inhibit HER2-driven cancer cell growth
    • Vazquez-Martin A, Oliveras-Ferraros C, Cufi S, Del Barco S, Martin-Castillo B, Menendez JA (2011) Lapatinib, a dual HER1/HER2 tyrosine kinase inhibitor, augments basal cleavage of HER2 extracellular domain (ECD) to inhibit HER2-driven cancer cell growth. J Cell Physiol 226: 52-57
    • (2011) J Cell Physiol , vol.226 , pp. 52-57
    • Vazquez-Martin, A.1    Oliveras-Ferraros, C.2    Cufi, S.3    Del Barco, S.4    Martin-Castillo, B.5    Menendez, J.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.