메뉴 건너뛰기




Volumn 53, Issue 7, 2012, Pages 3766-3781

Evaluation and quantitation of intact wax esters of human meibum by gas-liquid chromatography-ion trap mass spectrometry

Author keywords

[No Author keywords available]

Indexed keywords

ESTER DERIVATIVE; HEPTADECANOIC ACID; OLEIC ACID; PALMITIC ACID; PALMITOLEIC ACID; STEARIC ACID; UNCLASSIFIED DRUG; WAX ESTER; ESTER; WAX;

EID: 84865838829     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-9333     Document Type: Article
Times cited : (52)

References (34)
  • 2
    • 79953732385 scopus 로고    scopus 로고
    • The international workshop on meibomian gland dysfunction: Report of the subcommittee on tear film lipids and lipid- protein interactions in health and disease
    • Green-Church KB, Butovich I, Willcox M, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on tear film lipids and lipid- protein interactions in health and disease. Invest Ophthalmol Vis Sci. 2011;52:1979-1993
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 1979-1993
    • Green-Church, K.B.1    Butovich, I.2    Willcox, M.3
  • 3
    • 0842288713 scopus 로고    scopus 로고
    • Evaporation from the ocular surface
    • Mathers W. Evaporation from the ocular surface. Exp Eye Res. 2004;78:389-394
    • (2004) Exp Eye Res , vol.78 , pp. 389-394
    • Mathers, W.1
  • 4
    • 73949102082 scopus 로고    scopus 로고
    • Meibomian glands. Part II: Physiology, characteristics, distribution and function of meibomian oil
    • Knop E, Knop N, Schirra F. Meibomian glands. Part II: physiology, characteristics, distribution and function of meibomian oil. Ophthalmologe. 2009;106:884-892
    • (2009) Ophthalmologe , vol.106 , pp. 884-892
    • Knop, E.1    Knop, N.2    Schirra, F.3
  • 5
    • 33646895865 scopus 로고    scopus 로고
    • Laboratory findings in tear fluid analysis
    • Ohashi Y, Dogru M, Tsubota K. Laboratory findings in tear fluid analysis. Clin Chim Acta. 2006;369:17-28
    • (2006) Clin Chim Acta , vol.369 , pp. 17-28
    • Ohashi, Y.1    Dogru, M.2    Tsubota, K.3
  • 6
    • 70350356367 scopus 로고    scopus 로고
    • The meibomian puzzle: Combining pieces together
    • Butovich IA. The meibomian puzzle: combining pieces together. Prog Retin Eye Res. 2009;28:483-498
    • (2009) Prog Retin Eye Res , vol.28 , pp. 483-498
    • Butovich, I.A.1
  • 7
    • 79957546505 scopus 로고    scopus 로고
    • Lipidomics of human meibomian gland secretions: Chemistry, biophysics, and physiological role of meibomian lipids
    • Butovich IA. Lipidomics of human meibomian gland secretions: chemistry, biophysics, and physiological role of meibomian lipids. Prog Lipid Res. 2011;50:278-301
    • (2011) Prog Lipid Res , vol.50 , pp. 278-301
    • Butovich, I.A.1
  • 8
    • 0021825098 scopus 로고
    • The di- and triesters of the lipids of steer and human meibomian glands
    • Nicolaides N, Santos EC. The di- and triesters of the lipids of steer and human meibomian glands. Lipids. 1985;20:454-467
    • (1985) Lipids , vol.20 , pp. 454-467
    • Nicolaides, N.1    Santos, E.C.2
  • 9
    • 0023112174 scopus 로고
    • Identification by combined gas chromatography-mass spectrometry of constituent long-chain fatty acids and alcohols from the meibomian glands of the rat and a comparison with human meibomian lipids
    • Harvey DJ, Tiffany JM, Duerden JM, Pandher KS, Mengher LS. Identification by combined gas chromatography-mass spectrometry of constituent long-chain fatty acids and alcohols from the meibomian glands of the rat and a comparison with human meibomian lipids. J Chromatogr. 1987;414:253-263
    • (1987) J Chromatogr , vol.414 , pp. 253-263
    • Harvey, D.J.1    Tiffany, J.M.2    Duerden, J.M.3    Pandher, K.S.4    Mengher, L.S.5
  • 10
    • 0024422998 scopus 로고
    • The role of wax and sterol esters of meibomian secretions in chronic blepharitis
    • Osgood JK, Dougherty JM, McCulley JP. The role of wax and sterol esters of meibomian secretions in chronic blepharitis. Invest Ophthalmol Vis Sci. 1989;30:1958-1961
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , pp. 1958-1961
    • Osgood, J.K.1    Dougherty, J.M.2    McCulley, J.P.3
  • 11
  • 12
    • 38349137382 scopus 로고    scopus 로고
    • Differences in meibomian fatty acid composition in patients with meibomian gland dysfunction and aqueous-deficient dry eye
    • Joffre C, Souchier N, Gr ́egoire S, et al. Differences in meibomian fatty acid composition in patients with meibomian gland dysfunction and aqueous-deficient dry eye. Br J Ophthalmol. 2008;92:116-119
    • (2008) Br J Ophthalmol , vol.92 , pp. 116-119
    • Joffre, C.1    Souchier, N.2    Gŕegoire, S.3
  • 13
    • 53149111576 scopus 로고    scopus 로고
    • On the lipid composition of human meibum and tears: Comparative analysis of nonpolar lipids
    • Butovich IA. On the lipid composition of human meibum and tears: comparative analysis of nonpolar lipids. Invest Ophthalmol Vis Sci. 2008;49:3779-3789
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 3779-3789
    • Butovich, I.A.1
  • 14
    • 34248220964 scopus 로고    scopus 로고
    • Electrospray mass spectrometry of human hair wax esters
    • Fitzgerald M, Murphy RC. Electrospray mass spectrometry of human hair wax esters. J Lipid Res. 2007;48:1231-1246
    • (2007) J Lipid Res , vol.48 , pp. 1231-1246
    • Fitzgerald, M.1    Murphy, R.C.2
  • 15
    • 3343003035 scopus 로고    scopus 로고
    • Acid-catalyzed intra- and intermolecular acyl exchange in mono- and diglycerides
    • Isai SV, Usol'tsev AA, Stiba EN. Acid-catalyzed intra- and intermolecular acyl exchange in mono- and diglycerides. Chem Nat Compounds. 2003;39:325-329
    • (2003) Chem Nat Compounds , vol.39 , pp. 325-329
    • Isai, S.V.1    Usol'tsev, A.A.2    Stiba, E.N.3
  • 16
    • 70849130750 scopus 로고    scopus 로고
    • Human tear film and meibum. Very long chain wax esters and (O-acyl)-omegahydroxy fatty acids of meibum
    • Butovich IA, Wojtowicz JC, Molai M. Human tear film and meibum. Very long chain wax esters and (O-acyl)-omegahydroxy fatty acids of meibum. J Lipid Res. 2009;50:2471-2485
    • (2009) J Lipid Res , vol.50 , pp. 2471-2485
    • Butovich, I.A.1    Wojtowicz, J.C.2    Molai, M.3
  • 17
    • 84878130212 scopus 로고    scopus 로고
    • Mass spectra of methyl esters of fatty acids. Part 2, Available at, Accessed November 28, 2011
    • Mass spectra of methyl esters of fatty acids. Part 2. Branchedchain fatty acids. Available at: http://lipidlibrary.aocs.org/ms/ ms03a/index.htm. Accessed November 28, 2011
    • Branchedchain Fatty Acids
  • 18
    • 0017083606 scopus 로고
    • Composition of the neutral lipids of bovine meilbomian secretions
    • Baron C, Blough HA. Composition of the neutral lipids of bovine meilbomian secretions. J Lipid Res. 1976;17:373-376
    • (1976) J Lipid Res , vol.17 , pp. 373-376
    • Baron, C.1    Blough, H.A.2
  • 19
    • 0018093663 scopus 로고
    • Individual variations in human meibomian lipid composition
    • Tiffany JM. Individual variations in human meibomian lipid composition. Exp Eye Res. 1978;27:289-300
    • (1978) Exp Eye Res , vol.27 , pp. 289-300
    • Tiffany, J.M.1
  • 20
    • 0028804366 scopus 로고
    • Physiological functions of the meibomian glands
    • Tiffany JM. Physiological functions of the meibomian glands. Prog Ret Eye Res. 1995;14:47-74
    • (1995) Prog Ret Eye Res , vol.14 , pp. 47-74
    • Tiffany, J.M.1
  • 21
    • 0031814193 scopus 로고    scopus 로고
    • Meibomian gland lipids, evaporation, and tear film stability
    • Mathers WD, Lane JA. Meibomian gland lipids, evaporation, and tear film stability. Adv Exp Med Biol. 1998;438:349-360
    • (1998) Adv Exp Med Biol , vol.438 , pp. 349-360
    • Mathers, W.D.1    Lane, J.A.2
  • 22
    • 80054736960 scopus 로고    scopus 로고
    • Meibum lipid composition in Asians with dry eye disease
    • Lam SM, Tong L, Yong SS, et al. Meibum lipid composition in Asians with dry eye disease. PLoS One. 2011;6:e24339
    • (2011) PLoS One , vol.6
    • Lam, S.M.1    Tong, L.2    Yong, S.S.3
  • 23
    • 79952467442 scopus 로고    scopus 로고
    • On the presence of (O-acyl)-omega-hydroxy fatty acids and of their esters in human meibomian gland secretions
    • Butovich IA. On the presence of (O-acyl)-omega-hydroxy fatty acids and of their esters in human meibomian gland secretions. Invest Ophthalmol Vis Sci. 2011;52:639-641
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 639-641
    • Butovich, I.A.1
  • 24
    • 79952100523 scopus 로고    scopus 로고
    • Shotgun lipidomic analysis of human meibomian gland secretions with electrospray ionization tandem mass spectrometry
    • Chen J, Green-Church KB, Nichols KK. Shotgun lipidomic analysis of human meibomian gland secretions with electrospray ionization tandem mass spectrometry. Invest Ophthalmol Vis Sci. 2010;51:6220-6231
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 6220-6231
    • Chen, J.1    Green-Church, K.B.2    Nichols, K.K.3
  • 25
    • 0028884679 scopus 로고
    • Physical properties of insect cuticular hydrocarbons: The effects of chain length, methyl-branching and unsaturation
    • Gibbs A, Pomonis JG. Physical properties of insect cuticular hydrocarbons: the effects of chain length, methyl-branching and unsaturation. Comp Biochem Physiol B. 1995;112:243-249
    • (1995) Comp Biochem Physiol B , vol.112 , pp. 243-249
    • Gibbs, A.1    Pomonis, J.G.2
  • 26
    • 0014439936 scopus 로고
    • Melting points of synthetic wax esters
    • Iyengar BTR, Schlenk H. Melting points of synthetic wax esters. Lipids. 1969;4:28-30
    • (1969) Lipids , vol.4 , pp. 28-30
    • Iyengar, B.T.R.1    Schlenk, H.2
  • 28
    • 84856400748 scopus 로고    scopus 로고
    • Analysis of the composition of lipid in human meibum from normal infants, children, adolescents, adults, and adults with meibomian gland dysfunction using 1H-NMR spectroscopy
    • Shrestha RK, Borchman D, Foulks GN, Yappert MC, Milliner SE. Analysis of the composition of lipid in human meibum from normal infants, children, adolescents, adults, and adults with meibomian gland dysfunction using 1H-NMR spectroscopy. Invest Ophthalmol Vis Sci. 2011;52:7350-7358
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 7350-7358
    • Shrestha, R.K.1    Borchman, D.2    Foulks, G.N.3    Yappert, M.C.4    Milliner, S.E.5
  • 29
    • 33748616243 scopus 로고    scopus 로고
    • Influence of aging on the polar and neutral lipid profiles in human meibomian gland secretions
    • Sullivan BD, Evans JE, Dana MR, Sullivan DA. Influence of aging on the polar and neutral lipid profiles in human meibomian gland secretions. Arch Ophthalmol. 2006;124: 1286-1292
    • (2006) Arch Ophthalmol , vol.124 , pp. 1286-1292
    • Sullivan, B.D.1    Evans, J.E.2    Dana, M.R.3    Sullivan, D.A.4
  • 30
    • 34548244536 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometric analysis of lipids present in meibomian gland secretions
    • Butovich IA, Uchiyama E, Di Pascuale MA, McCulley JP. Liquid chromatography-mass spectrometric analysis of lipids present in meibomian gland secretions. Lipids. 2007;42:765-776
    • (2007) Lipids , vol.42 , pp. 765-776
    • Butovich, I.A.1    Uchiyama, E.2    Di Pascuale, M.A.3    McCulley, J.P.4
  • 31
    • 79951771809 scopus 로고    scopus 로고
    • Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye
    • Wojtowicz JC, Butovich IA, Uchiyama E, Aronowicz J, Agee S, McCulley JP. Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye. Cornea. 2011;30:308-314
    • (2011) Cornea , vol.30 , pp. 308-314
    • Wojtowicz, J.C.1    Butovich, I.A.2    Uchiyama, E.3    Aronowicz, J.4    Agee, S.5    McCulley, J.P.6
  • 32
    • 64349094606 scopus 로고    scopus 로고
    • Cholesteryl esters as a depot for very long chain fatty acids in human meibum
    • Butovich IA. Cholesteryl esters as a depot for very long chain fatty acids in human meibum. Lipid Res. 2009;50:501-513
    • (2009) Lipid Res , vol.50 , pp. 501-513
    • Butovich, I.A.1
  • 33
    • 77954310059 scopus 로고    scopus 로고
    • Fatty acid composition of cholesteryl esters of human meibomian gland secretions
    • Butovich IA. Fatty acid composition of cholesteryl esters of human meibomian gland secretions. Steroids. 2010;75:726-733
    • (2010) Steroids , vol.75 , pp. 726-733
    • Butovich, I.A.1
  • 34
    • 84455188797 scopus 로고    scopus 로고
    • Structural characterization of wax esters by electron ionization mass spectrometry
    • Urbanova K, Vrkoslav V, Valterova I, Hakova M, Cvacka J. Structural characterization of wax esters by electron ionization mass spectrometry. J Lipid Res. 2012;53:204-213.
    • (2012) J Lipid Res , vol.53 , pp. 204-213
    • Urbanova, K.1    Vrkoslav, V.2    Valterova, I.3    Hakova, M.4    Cvacka, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.