-
1
-
-
8844220536
-
Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series
-
Landles, C. and G. P. Bates (2004). "Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series. " EMBO Rep 5(10): 958-63.
-
(2004)
EMBO Rep
, vol.5
, Issue.10
, pp. 958-963
-
-
Landles, C.1
Bates, G.P.2
-
2
-
-
67650296271
-
Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model
-
Zhang, S., M. B. Feany, et al. (2009). "Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. " Dis Model Mech 2(5-6): 247-66.
-
(2009)
Dis Model Mech
, vol.2
, Issue.5-6
, pp. 247-266
-
-
Zhang, S.1
Feany, M.B.2
-
3
-
-
36949012566
-
Huntington disease models and human neuropathology: Similarities and differences
-
Vonsattel, J. P. (2008). "Huntington disease models and human neuropathology: similarities and differences. " Acta Neuropathol 115(1): 55-69.
-
(2008)
Acta Neuropathol
, vol.115
, Issue.1
, pp. 55-69
-
-
Vonsattel, J.P.1
-
4
-
-
42249109228
-
Rapid eye movement sleep disturbances in Huntington disease
-
Arnulf, I., J. Nielsen, et al. (2008). "Rapid eye movement sleep disturbances in Huntington disease. " Arch Neurol 65(4): 482-8.
-
(2008)
Arch Neurol
, vol.65
, Issue.4
, pp. 482-488
-
-
Arnulf, I.1
Nielsen, J.2
-
5
-
-
58949098040
-
Neurobiology of sleep disturbances in neurodegenerative disorders
-
Gagnon, J. F., D. Petit, et al. (2008). "Neurobiology of sleep disturbances in neurodegenerative disorders. " Curr Pharm Des 14(32): 3430-45.
-
(2008)
Curr Pharm Des
, vol.14
, Issue.32
, pp. 3430-3445
-
-
Gagnon, J.F.1
Petit, D.2
-
6
-
-
77954424684
-
How vital is sleep in Huntington's disease?
-
Goodman, A. O. and R. A. Barker "How vital is sleep in Huntington's disease?" J Neurol 257(6): 882-97.
-
J Neurol
, vol.257
, Issue.6
, pp. 882-897
-
-
Goodman, A.O.1
Barker, R.A.2
-
7
-
-
77954887739
-
Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease
-
Wulff, K., S. Gatti, et al. "Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease. " Nat Rev Neurosci 11(8): 589-99.
-
Nat Rev Neurosci
, vol.11
, Issue.8
, pp. 589-599
-
-
Wulff, K.1
Gatti, S.2
-
8
-
-
67649390748
-
Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease
-
Pallier, P. N. and A. J. Morton (2009). "Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease. " Brain Res 1279: 90-8.
-
(2009)
Brain Res
, vol.1279
, pp. 90-98
-
-
Pallier, P.N.1
Morton, A.J.2
-
9
-
-
67651097622
-
The genetic and molecular regulation of sleep: From fruit flies to humans
-
Cirelli, C. (2009). "The genetic and molecular regulation of sleep: from fruit flies to humans. " Nat Rev Neurosci 10(8): 549-60.
-
(2009)
Nat Rev Neurosci
, vol.10
, Issue.8
, pp. 549-560
-
-
Cirelli, C.1
-
10
-
-
77954867762
-
Circadian rhythms and memory formation
-
Gerstner, J. R. and J. C. Yin "Circadian rhythms and memory formation. " Nat Rev Neurosci 11(8): 577-88.
-
Nat Rev Neurosci
, vol.11
, Issue.8
, pp. 577-588
-
-
Gerstner, J.R.1
Yin, J.C.2
-
11
-
-
0034629130
-
Correlates of sleep and waking in Drosophila melanogaster
-
Mar 10 PubMed PMID: 10710313
-
Shaw PJ, Cirelli C, Greenspan RJ, Tononi G. Correlates of sleep and waking in Drosophila melanogaster. Science. 2000 Mar 10;287(5459):1834-7. PubMed PMID: 10710313.
-
(2000)
Science.
, vol.287
, Issue.5459
, pp. 1834-1837
-
-
Shaw, P.J.1
Cirelli, C.2
Greenspan, R.J.3
Tononi, G.4
-
12
-
-
34447530305
-
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
-
Dietzl, G., D. Chen, et al. (2007). "A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. " Nature 448(7150): 151-6.
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 151-156
-
-
Dietzl, G.1
Chen, D.2
-
13
-
-
0038601743
-
Awakening to the behavioral analysis of sleep in Drosophila
-
Feb Review. PubMed PMID: 12568240
-
Shaw P. Awakening to the behavioral analysis of sleep in Drosophila. J Biol Rhythms. 2003 Feb;18(1):4-11. Review. PubMed PMID: 12568240.
-
(2003)
J Biol Rhythms.
, vol.18
, Issue.1
, pp. 4-11
-
-
Shaw, P.1
-
14
-
-
16844367444
-
Essentials of sleep recordings in Drosophila: Moving beyond sleep time
-
Andretic, R. and P. J. Shaw (2005). "Essentials of sleep recordings in Drosophila: moving beyond sleep time. " Methods Enzymol 393: 759-72.
-
(2005)
Methods Enzymol
, vol.393
, pp. 759-772
-
-
Andretic, R.1
Shaw, P.J.2
-
15
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand, A. H. and N. Perrimon (1993). "Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. " Development 118(2): 401-15.
-
(1993)
Development
, vol.118
, Issue.2
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
16
-
-
84873396288
-
-
The Huntington's Disease Collaborative Research Group
-
The Huntington's Disease Collaborative Research Group, 1993.
-
(1993)
-
-
-
17
-
-
54149098124
-
Large ventral lateral neurons modulate arousal and sleep in Drosophila
-
Sheeba, V., K. J. Fogle, et al. (2008). "Large ventral lateral neurons modulate arousal and sleep in Drosophila. " Curr Biol 18(20): 1537-45.
-
(2008)
Curr Biol
, vol.18
, Issue.20
, pp. 1537-1545
-
-
Sheeba, V.1
Fogle, K.J.2
-
18
-
-
37549004790
-
Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm
-
Romero, E., G. H. Cha, et al. (2008). "Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm. " Neuron 57(1): 27-40.
-
(2008)
Neuron
, vol.57
, Issue.1
, pp. 27-40
-
-
Romero, E.1
Cha, G.H.2
-
19
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Aug 8 PubMed PMID: 9267033
-
Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, Scherzinger E, Wanker EE, Mangiarini L, Bates GP. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell. 1997 Aug 8;90(3):537-48. PubMed PMID: 9267033.
-
(1997)
Cell.
, vol.90
, Issue.3
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
20
-
-
0036533795
-
Lessons from animal models of Huntington's disease
-
Apr Review. PubMed PMID: 11932021
-
Rubinsztein DC. Lessons from animal models of Huntington's disease. Trends Genet. 2002 Apr;18(4):202-9. Review. PubMed PMID: 11932021.
-
(2002)
Trends Genet.
, vol.18
, Issue.4
, pp. 202-209
-
-
Rubinsztein, D.C.1
-
21
-
-
0036165417
-
Mouse models of Huntington's disease
-
Jan Review. PubMed PMID: 11804649
-
Menalled LB, Chesselet MF. Mouse models of Huntington's disease. Trends Pharmacol Sci. 2002 Jan;23(1):32-9. Review. PubMed PMID: 11804649.
-
(2002)
Trends Pharmacol Sci.
, vol.23
, Issue.1
, pp. 32-39
-
-
Menalled, L.B.1
Chesselet, M.F.2
-
22
-
-
0033757718
-
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
-
Nov PubMed PMID: 11062468
-
Dragatsis I, Levine MS, Zeitlin S. Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nat Genet. 2000 Nov;26(3):300-6. PubMed PMID: 11062468.
-
(2000)
Nat Genet.
, vol.26
, Issue.3
, pp. 300-306
-
-
Dragatsis, I.1
Levine, M.S.2
Zeitlin, S.3
-
23
-
-
2642646258
-
Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues
-
Apr PubMed PMID: 9502734
-
Dragatsis I, Efstratiadis A, Zeitlin S. Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues. Development. 1998 Apr;125(8):1529-39. PubMed PMID: 9502734.
-
(1998)
Development.
, vol.125
, Issue.8
, pp. 1529-1539
-
-
Dragatsis, I.1
Efstratiadis, A.2
Zeitlin, S.3
-
24
-
-
72249116078
-
Normal and mutant HTT interact to affect clinical severity and progression in Huntington disease
-
Aziz, N. A., C. K. Jurgens, et al. (2009). "Normal and mutant HTT interact to affect clinical severity and progression in Huntington disease. " Neurology 73(16): 1280-5.
-
(2009)
Neurology
, vol.73
, Issue.16
, pp. 1280-1285
-
-
Aziz, N.A.1
Jurgens, C.K.2
-
25
-
-
28644433087
-
Normal huntingtin function: An alternative approach to Huntington's disease
-
Cattaneo, E., C. Zuccato, et al. (2005). "Normal huntingtin function: an alternative approach to Huntington's disease. " Nat Rev Neurosci 6(12): 919-30.
-
(2005)
Nat Rev Neurosci
, vol.6
, Issue.12
, pp. 919-930
-
-
Cattaneo, E.1
Zuccato, C.2
-
26
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
Sep 25 PubMed PMID: 14527431
-
Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, Gordesky-Gold B, Sintasath L, Bonini NM, Goldstein LS. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 2003 Sep 25;40(1):25-40. PubMed PMID: 14527431.
-
(2003)
Neuron.
, vol.40
, Issue.1
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.9
-
27
-
-
54949140807
-
Protective role of Engrailed in a Drosophila model of Huntington's disease
-
Mugat, B., M. L. Parmentier, et al. (2008). "Protective role of Engrailed in a Drosophila model of Huntington's disease. " Hum Mol Genet 17(22): 3601-16.
-
(2008)
Hum Mol Genet
, vol.17
, Issue.22
, pp. 3601-3616
-
-
Mugat, B.1
Parmentier, M.L.2
-
28
-
-
45149107487
-
Mechanisms of neurodegeneration in Huntington's disease
-
Gil, J. M. and A. C. Rego (2008). "Mechanisms of neurodegeneration in Huntington's disease. " Eur J Neurosci 27(11): 2803-20.
-
(2008)
Eur J Neurosci
, vol.27
, Issue.11
, pp. 2803-2820
-
-
Gil, J.M.1
Rego, A.C.2
-
29
-
-
52049085768
-
Pathophysiology of Huntington's disease: From huntingtin functions to potential treatments
-
Aug Review. PubMed PMID: 18607213
-
Roze E, Saudou F, Caboche J. Pathophysiology of Huntington's disease: from huntingtin functions to potential treatments. Curr Opin Neurol. 2008 Aug;21(4):497-503. Review. PubMed PMID: 18607213.
-
(2008)
Curr Opin Neurol.
, vol.21
, Issue.4
, pp. 497-503
-
-
Roze, E.1
Saudou, F.2
Caboche, J.3
-
30
-
-
0025916521
-
Nocturnal sleep in Huntington's disease
-
Wiegand, M., A. A. Moller, et al. (1991). "Nocturnal sleep in Huntington's disease. " J Neurol 238(4): 203-8.
-
(1991)
J Neurol
, vol.238
, Issue.4
, pp. 203-208
-
-
Wiegand, M.1
Moller, A.A.2
-
31
-
-
16344373911
-
Sleep and neurodegenerative diseases
-
Bhatt, M. H., N. Podder, et al. (2005). "Sleep and neurodegenerative diseases. " Semin Neurol 25(1): 39-51.
-
(2005)
Semin Neurol
, vol.25
, Issue.1
, pp. 39-51
-
-
Bhatt, M.H.1
Podder, N.2
-
32
-
-
0035282338
-
Sleep and the fruit fly
-
Mar Review. PubMed PMID: 11182453
-
Greenspan RJ, Tononi G, Cirelli C, Shaw PJ. Sleep and the fruit fly. Trends Neurosci. 2001 Mar;24(3):142-5. Review. PubMed PMID: 11182453.
-
(2001)
Trends Neurosci.
, vol.24
, Issue.3
, pp. 142-145
-
-
Greenspan, R.J.1
Tononi, G.2
Cirelli, C.3
Shaw, P.J.4
-
33
-
-
1542267796
-
Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease
-
Lee, W. C., M. Yoshihara, et al. (2004). "Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease. " Proc Natl Acad Sci U S A 101(9): 3224-9.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.9
, pp. 3224-3229
-
-
Lee, W.C.1
Yoshihara, M.2
-
34
-
-
10744225124
-
Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease
-
Djousse, L., B. Knowlton, et al. (2003). "Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease. " Am J Med Genet A 119A(3): 279-82.
-
(2003)
Am J Med Genet A
, vol.119 A
, Issue.3
, pp. 279-282
-
-
Djousse, L.1
Knowlton, B.2
-
35
-
-
0037118054
-
Stress response genes protect against lethal effects of sleep deprivation in Drosophila
-
May 16 PubMed PMID: 12015603
-
Shaw PJ, Tononi G, Greenspan RJ, Robinson DF. Stress response genes protect against lethal effects of sleep deprivation in Drosophila. Nature. 2002 May 16;417(6886):287-91. PubMed PMID: 12015603.
-
(2002)
Nature.
, vol.417
, Issue.6886
, pp. 287-291
-
-
Shaw, P.J.1
Tononi, G.2
Greenspan, R.J.3
Robinson, D.F.4
|