Genotyping of Candida parapsilosis from three neonatal intensive care units (NICUs) using a panel of five multilocus microsatellite markers: Broad genetic diversity and a cluster of related strains in one NICU

Infection, Genetics and Evolution

Volumn 12, Issue 8, 2012, Pages 1654-1660

  Reiss, Errol ^a   Lasker, Brent A ^a   Lott, Timothy J ^a   Bendel, Catherine M ^b   Kaufman, David A ^c   Hazen, Kevin C ^c,e   Wade, Kelly C ^d   McGowan, Karin L ^d   Lockhart, Shawn R ^a  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Candida parapsilosis; Microsatellite; Molecular epidemiology; Neonatal intensive care unit

Indexed keywords

BACTERIAL DNA;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM ISOLATE; CANDIDA PARAPSILOSIS; FUNGUS TRANSMISSION; GENERAL HOSPITAL; GENETIC MARKER; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HETEROZYGOSITY; HOSPITAL PATIENT; HUMAN; INFANT; MICROSATELLITE MARKER; MOLECULAR EPIDEMIOLOGY; NEWBORN INTENSIVE CARE; NONHUMAN; PRIORITY JOURNAL; TRINUCLEOTIDE MARKER; UNITED STATES;

CANDIDA; CANDIDIASIS; CLUSTER ANALYSIS; COHORT STUDIES; CROSS INFECTION; GENETIC MARKERS; GENETIC VARIATION; GENOTYPE; HUMANS; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; MICROSATELLITE REPEATS; MOLECULAR EPIDEMIOLOGY; PHYLOGENY;

CANDIDA PARAPSILOSIS;

EID: 84865823722     PISSN: 15671348     EISSN: 15677257     Source Type: Journal    
DOI: 10.1016/j.meegid.2012.06.012     Document Type: Article

References (36)

1. Agapow P.M., Burt A. Indices of multilocus linkage disequilibrium. Mol. Ecol. Notes 2001, 1:101-102.
2. Asmundsdóttir L.R., Erlendsdóttir H., Haraldsson G., Guo H., Xu J., Gottfredsson M. Molecular epidemiology of candidemia: evidence of clusters of smoldering nosocomial infections. Clin. Infect. Dis. 2008, 47:e17-e24.
3. Brillowska-Dabrowska A., Schön T., Pannanusorn S., Lönnbro N., Bernhoff L., Bonnedal J., Haggstrom J., Wistedt A., Fernandez V., Arendrup M.C. A nosocomial outbreak of Candida parapsilosis in southern Sweden verified by genotyping. Scand. J. Infect. Dis. 2009, 41:135-142.
4. Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature 2009, 459(7247):657-662.
5. Carruba G., Pontieri E., De Bernardis F., Martino P., Cassone A. DNA fingerprinting and electrophoretic karyotype of environmental and clinical isolates of Candida parapsilosis. J. Clin. Microbiol. 1991, 29:916-922.
6. Cavalli-Sforza L.L., Edwards A.W. Phylogenetic analysis. Models and estimation procedures. Am. J. Hum. Genet. 1967, 19:233-257.
7. Clark T.A., Slavinski S.A., Morgan J., Lott T., Arthington-Skaggs B.A., Brandt M.E., Webb R.M., Currier M., Flowers R.H., Fridkin S.K., Hajjeh R.A. Epidemiologic and molecular characterization of an outbreak of Candida parapsilosis bloodstream infections in a community hospital. J. Clin. Microbiol. 2004, 42:4468-4472.
8. Cohen-Wolkowiez M., Moran C., Benjamin D.K., Cotton C.M., Clark R.H., Benjamin D.K., Smith P.B. Early and late onset sepsis in late preterm infants. Pediatr. Infect. Dis. J. 2009, 28:1052-1056.
9. Enger L., Joly S., Pujol C., Simonson P., Pfaller M., Soll D.R. Cloning and characterization of a complex DNA fingerprinting probe for Candida parapsilosis. J. Clin. Microbiol. 2001, 39:658-669.
10. Fridkin S.K., Kaufman D., Edwards J.R., Shetty S., Horan T. Changing incidence of Candida bloodstream infections among NICU patients in the United States: 1995-2004. Pediatrics 2006, 117:1680-1687.
11. Fundyga R.E., Kuykendall R.J., Lee-Yang W., Lott T.J. Evidence for aneuploidy and recombination in the human commensal yeast Candida parapsilosis. Infect. Genetics Evol. 2004, 4:37-43.
12. Hazen K.C., Howell S.A. Candida, Cryptococcus and other yeasts of medical importance. Manual of Clinical Microbiology 2006, vol. 2:1762-1788. ASM Press, Washington DC. ninth ed.
13. Hunter P.R., Gaston M.A. Numerical index of discriminatory ability of typing systems: an application of Simpson's index of diversity. J. Clin. Microbiol. 1988, 26:2465-2466.
14. Johnsson H., Ewald U. The rate of candidaemia in preterm infants born at a gestational age of 23-28 weeks is inversely correlated to gestational age. Acta Paediatr. 2004, 93:954-958.
15. Kaufman D. Fungal infection in the very low birthweight infant. Curr. Opin. Infect. Dis. 2004, 17:253-259.
16. Kaufman D.A., Manzoni P. Strategies to prevent invasive candidal infection in extremely preterm infants. Clin. Perinatol. 2010, 37:611-628.
17. Koskinen M.T., Hirvonen H., Landry P.A., Primmer C.R. The benefits of increasing the number of microsatellites utilized in genetic population studies: an empirical perspective. Hereditas 2004, 141:61-67.
18. Lasker B.A., Butler G., Lott T.J. Molecular genotyping of Candida parapsilosis Group I clinical isolates by analysis of polymorphic microsatellite markers. J. Clin. Microbiol. 2006, 44:750-759.
19. Lehmann P.F., Lin D., Lasker B.A. Genotypic identification and characterization of species and strains within the genus Candida by using random amplified polymorphic DNA. J. Clin. Microbiol. 1992, 30:3249-3254.
20. Liu K., Muse S.V. PowerMarker: an integrated analysis environment for genetic marker analysis. Bioinformatics 2005, 21:2128-2129.
21. Manzoni P., Rizzollo S., Franco C., Gallo E., Galletto P., Boano E., Mostert M., Benjamin D.K., Jacqz-Aigrain E., Farina D. Role of echinocandins in the management of fungal infections in neonates. Matern. Fetal Neonatal Med. 2010, 23(Suppl. 3):49-52.
22. Odds F.C., Jacobsen M.D. Multilocus sequence typing of pathogenic Candida species. Eukaryot. Cell 2008, 7:1075-1084.
23. Page R.D.M. TREEVIEW: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 1996, 12:357-358.
24. Patel S.J., Graham P.L. Use of molecular typing in infection control. Pediatr. Infect. Dis. J. 2007, 26:527-529.
25. Reiss E., Lasker B.A., Iqbal N.J., James M.J., Arthington-Skaggs B.A. Molecular epidemiology of Candida parapsilosis sepsis from outbreak investigations in neonatal intensive care units. Infect. Genet. Evol. 2008, 8:103-109.
26. Sabino R., Sampaio P., Rosado L., Stevens D.A., Clemons K.V., Pais C. New polymorphic microsatellite markers able to distinguish among Candida parapsilosis senso strictu isolates. J. Clin. Microbiol. 2010, 48:1677-1682.
27. Sarvikivi E., Lyytikäinen O., Soll D.R., Pujol C., Pfaller M.A., Richardson M., Koukila-Kähkölä P., Luukkainen P., Saxén H. Emergence of fluconazole resistance in a Candida parapsilosis strain that caused infections in a neonatal intensive care unit. J. Clin. Microbiol. 2005, 43:2729-2735.
28. Stoll B.J., Hansen N., Fanaroff A.A., Wright L.L., Carlo W.A., Ehrenkranz R.A., Lemons J.A., Donovan E.F., Stark A.R., Tyson J.E., Oh W., Bauer C.R., Korones S.B., Shankaran S., Laptook A.R., Stevenson D.K., Papile L.A., Poole W.K. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 2002, 110:285-291.
29. Tavanti A., Davidson A.D., Gow N.A.R., Maiden M.C.J. Candida orthopsilosis and Candida metapsilosis spp. nov. to replace Candida parapsilosis groups II and III. J. Clin. Microbiol. 2005, 43:284-292.
30. Traoré O., Springthorpe V.S., Sattar S.A. A quantitative study of the survival of two species of Candida on porous and non-porous environmental surfaces and hands. J. Appl. Microbiol. 2002, 92:549-555.
31. Trofa D., Gácser A., Nosanchuk J.D. Candida parapsilosis, an emerging fungal pathogen. Clin. Microbiol. Rev. 2008, 21:606-625.
32. Tumbarello M., Posteraro B., Trecarichi E.M., Fiori B., Rossi M., Porta R., de Gaetano Donati K., La Sorda M., Spanu T., Fadda G., Cauda R., Sanguinetti M. Biofilm production by Candida species and inadequate antifungal therapy as predictors of mortality for patients with candidemia. J. Clin. Microbiol. 2007, 45:1843-1850.
33. van Asbeck E.C., Clemons K.V., Stevens D.A. Candida parapsilosis: a review of its epidemiology, pathogenesis, clinical aspects, typing and antimicrobial susceptibility. Crit. Rev. Microbiol. 2009, 35:283-309.
34. van Asbeck E.C., Clemons K.V., Markham A.N., Stevens D.A. Correlation of restriction fragment length polymorphism genotyping with internal transcribed spacer sequence, randomly amplified polymorphic DNA and multilocus sequence groupings for Candida parapsilosis. Mycoses 2009, 52:493-498.
35. Yildirim M., Sahin I., Kucukbayrak A., Ozdemir D., Tevfik Yavuz M., Oksuz S., Cakir S. Hand carriage of Candida species and risk factors in hospital personnel. Mycoses 2007, 50:189-192.
36. Zaoutis T. Candidemia in children. Curr. Med. Res. Opin. 2010, 26:1761-1768.