Curcumin suppresses ovalbumin-induced allergic conjunctivitis

Molecular Vision

Volumn 18, Issue , 2012, Pages 1966-1972

  Chung, So Hyang ^a,b   Choi, Seong Hyun ^a   Choi, Jin A ^a   Chuck, Roy S ^b   Joo, Choun Ki ^a  

^a The Catholic University of Korea   (South Korea)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMIN; IMMUNOGLOBULIN E ANTIBODY; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 4; INTERLEUKIN 5; OVALBUMIN;

ALLERGIC CONJUNCTIVITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG MECHANISM; ENZYME INHIBITION; EOSINOPHIL COUNT; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNE RESPONSE; IMMUNOMODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TH2 CELL; WESTERN BLOTTING;

ALLERGENS; ALUM COMPOUNDS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL MOVEMENT; CONJUNCTIVA; CONJUNCTIVITIS, ALLERGIC; CURCUMIN; EOSINOPHILS; FEMALE; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; INJECTIONS, INTRAPERITONEAL; INTERLEUKIN-4; INTERLEUKIN-5; LYMPH NODES; MICE; MICE, INBRED BALB C; NITRIC OXIDE SYNTHASE TYPE II; OVALBUMIN; SPLEEN;

EID: 84865822089     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Trocme SD, Sra KK. Spectrum of ocular allergy. Curr Opin Allergy Clin Immunol 2002; 2:423-7. [PMID: 12582327]
2. Metz DP, Hingorani M, Calder VL, Buckley RJ, Lightman SL. T-cell cytokines in chronic allergic eye disease. J Allergy Clin Immunol 1997; 100:817-24. [PMID: 9438492]
3. Calder VL, Jolly G, Hingorani M, Adamson P, Leonardi A, Secchi AG, Buckley RJ, Lightman S. Cytokine production and mRNA expression by conjunctival T-cell lines in chronic allergic eye disease. Clin Exp Allergy 1999; 29:1214-22. [PMID: 10469030]
4. Leonardi A, DeFranchis G, Zancanaro F, Crivellari G, De Paoli M, Plebani M, Secchi AG. Identification of local Th2 and Th0 lymphocytes in vernal conjunctivitis by cytokine flow cytometry. Invest Ophthalmol Vis Sci 1999; 40:3036-40. [PMID: 10549670]
5. Abelson MB, Chambers WA, Smith LM. Conjunctival allergen challenge. A clinical approach to studying allergic conjunctivitis. Arch Ophthalmol 1990; 108:84-8. [PMID: 2297337]
6. Bonini S, Vecchione A, Naim DM, Allansmith MR, Balsano F. Inflammatory changes in conjunctival scrapings after allergen provocation in humans. J Allergy Clin Immunol 1988; 82:462-9. [PMID: 3170994]
7. Hingorani M, Calder V, Jolly G, Buckley RJ, Lightman SL. Eosinophil surface antigen expression and cytokine production vary in different ocular allergic diseases. J Allergy Clin Immunol 1998; 102:821-30. [PMID: 9819300]
8. Brouet I, Ohshima H. Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 1995; 206:533-40. [PMID: 7530002]
9. Chan MM, Huang HI, Fenton MR, Fong D. In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties. Biochem Pharmacol 1998; 55:1955-62. [PMID: 9714315]
10. Abe Y, Hashimoto S, Horie T. Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol Res 1999; 39:41-7. [PMID: 10051376]
11. Lee JC, Kinniry PA, Arguiri E, Serota M, Kanterakis S, Chatterjee S, Solomides CC, Javvadi P, Koumenis C, Cengel KA, Christofidou-Solomidou M. Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice. Radiat Res 2010; 173:590-601. [PMID: 20426658]
12. Ram A, Das M, Ghosh B. Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs. Biol Pharm Bull 2003; 26:1021-4. [PMID: 12843631]
13. Kurup VP, Barrios CS. Immunomodulatory effects of curcumin in allergy. Mol Nutr Food Res 2008; 52:1031-9. [PMID: 18398870]
14. Kurup VP, Barrios CS, Raju R, Johnson BD, Levy MB, Fink JN. Immune response modulation by curcumin in a latex allergy model. Clin Mol Allergy 2007; 5:1. [PMID: 17254346]
15. Moon DO, Kim MO, Lee HJ, Choi YH, Park YM, Heo MS, Kim GY. Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide. Biochem Biophys Res Commun 2008; 375:275-9. [PMID: 18706396]
16. Kim GY, Kim KH, Lee SH, Yoon MS, Lee HJ, Moon DO, Lee CM, Ahn SC, Park YC, Park YM. Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets. J Immunol 2005; 174:8116-24. [PMID: 15944320]
17. Chung S-H, Nam K-H, Kweon M-N. Staphylococcus aureus accelerates an experimental allergic conjunctivitis by Tolllike receptor 2-dependent manner. Clin Immunol 2009; 131:170-7. [PMID: 19358332]
18. Fukushima A, Yamaguchi T, Ishida W, Fukata K, Ueno H. TLR2 agonist ameliorates murine experimental allergic conjunctivitis by inducing CD4 positive T-cell apoptosis rather than by affecting the Th1/Th2 balance. Biochem Biophys Res Commun 2006; 339:1048-55. [PMID: 16337148]
19. Chung SH, Choi SH, Cho KJ, Joo CK. Toll-like receptor 4 signalling attenuates experimental allergic conjunctivitis. Clin Exp Immunol 2011; 164:275-81. [PMID: 21391988]
20. Ozaki A, Seki Y, Fukushima A, Kubo M. The control of allergic conjunctivitis by suppressor of cytokine signaling (SOCS)3 and SOCS5 in a murine model. J Immunol 2005; 175:5489-97. [PMID: 16210657]
21. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992; 6:3051-64. [PMID: 1381691]
22. Ko SM, Kim MK, Kim JC. The role of nitric oxide in experimental allergic conjunctivitis. Cornea 2000; 19:84-91. [PMID: 10632015]
23. Meijer F, Van Delft JL, Garrelds IM, Van Haeringen NJ, Kijlstra A. Nitric oxide plays a role as a mediator of conjunctival edema in experimental allergic conjunctivitis. Exp Eye Res 1996; 62:359-65. [PMID: 8795454]
24. Hebestreit H, Dibbert B, Balatti I, Braun D, Schapowal A, Blaser K, Simon HU. Disruption of fas receptor signaling by nitric oxide in eosinophils. J Exp Med 1998; 187:415-25. [PMID: 9449721]
25. Ferreira HH, Medeiros MV, Lima CS, Flores CA, Sannomiya P, Autunes E, De Nucci G. Inhibition of eosinophil chemotaxis by chronic blockade of nitric oxide biosynthesis. Eur J Pharmacol 1996; 310:201-7. [PMID: 8884218]