Long pressure reactivity index (L-PRx) as a measure of autoregulation correlates with outcome in traumatic brain injury patients

Acta Neurochirurgica

Volumn 154, Issue 9, 2012, Pages 1575-1581

  Sánchez Porras, Renán ^a,c   Santos, Edgar ^a   Czosnyka, Marek ^b   Zheng, Zelong ^a   Unterberg, Andreas W ^a   Sakowitz, Oliver W ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cerebral autoregulation; Low frequency pressure reactivity index; Microdialysis; Neuromonitoring; Outcome; Pressure reactivity index; Traumatic brain injury

Indexed keywords

GLUCOSE; LACTIC ACID; PYRUVIC ACID;

ADULT; ARTICLE; AUTOREGULATION; BRAIN PERFUSION; CEREBRAL AUTOREGULATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLASGOW COMA SCALE; HEAD INJURY; HEMODYNAMIC MONITORING; HUMAN; INTRACRANIAL PRESSURE; INTRACRANIAL PRESSURE MONITORING; LONG PRESSURE REACTIVITY INDEX; MALE; MEAN ARTERIAL PRESSURE; MICRODIALYSIS; MORTALITY; NERVOUS SYSTEM PARAMETERS; PERFUSION PRESSURE; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; SURVIVAL RATE; TRAUMATIC BRAIN INJURY; TREATMENT OUTCOME;

ADULT; ALGORITHMS; ARTERIAL PRESSURE; BLOOD GLUCOSE; BRAIN; BRAIN INJURIES; DISABILITY EVALUATION; FEMALE; GLUTAMIC ACID; HOMEOSTASIS; HUMANS; INTRACRANIAL PRESSURE; LACTIC ACID; MALE; PROGNOSIS; PYRUVIC ACID; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 84865805115     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-012-1423-0     Document Type: Article

References (24)

1. Aaslid R, Lindegaard KF, Sorteberg W, Nornes H (1989) Cerebral autoregulation dynamics in humans. Stroke 20:45-52 (Pubitemid 19040212)
2. Chamoun R, SukiD,Gopinath SP,Goodman JC, RobertsonC (2010) Role of extracellular glutamate measured by cerebralmicrodialysis in severe traumatic brain injury. J Neurosurg 113:564-570
3. Chan TV, Ng SC, Lam JM, Poon WS, Gin T (2005) Monitoring of autoregulation using intracerebral microdialysis in patients with severe head injury. Acta Neurochir Suppl 95:113-116
4. Czosnyka M, Brady K, Reinhard M, Smielewski P, Steiner LA (2009) Monitoring of cerebrovascular autoregulation: Facts, myths, and missing links. Neurocrit Care 10:373-386
5. Czosnyka M, Smielewski P, Kirkpatrick P, Laing RJ, Menon D, Pickard JD (1997) Continuous assessment of the cerebral vasomotor reactivity in head injury. Neurosurgery 41:11-19 (Pubitemid 27282076)
6. Czosnyka M, Smielewski P, Kirkpatrick P, Piechnik S, Laing R, Pickard JD (1998) Continuous monitoring of cerebrovascular pressure-reactivity in head injury. Acta Neurochir Suppl 71:74-77 (Pubitemid 128444362)
7. Hejcl A, Bolcha M, Procházka J, Hušková E, Sameš M (2011) Elevated intracranial pressure, low cerebral perfusion pressure, and impaired brain metabolism correlate with fatal outcome after severe brain injury. Cen Eur Neurosurg. doi:10.1055/s-0031-1275745
8. Jaeger M, Schuhmann MU, Soehle M, Meixensberger J (2006) Continuous assessment of cerebrovascular autoregulation after traumatic brain injury using brain tissue oxygen pressure reactivity. Crit Care Med 34:1783-1788 (Pubitemid 43810063)
9. Lang EW, Lagopoulos J, Griffith J, Yip K, Yam A, Mudaliar Y, Mehdorn HM, Dorsch NW (2003) Cerebral vasomotor reactivity testing in head injury: The link between pressure and flow. J Neurol Neurosurg Psychiatry 74:1053-1059
10. Len TK, Neary JP (2011) Cerebrovascular pathophysiology following mild traumatic brain injury. Clin Physiol Funct Imaging 31:85-93
11. Low D, Kuralmani V, Ng SK, Lee KK, Ng I, Ang BT (2009) Prediction of outcome utilizing both physiological and biochemical parameters in severe head injury. J Neurotrauma 26:1177-1182
12. Paulson OB, Strandgaard S, Edvinsson L (1990) Cerebral autoregulation. Cerebrovasc Brain Metab Rev 2:161-192
13. Rangel-Castilla L, Gasco J, Nauta HJ, Okonkwo DO, Robertson CS (2008) Cerebral pressure autoregulation in traumatic brain injury. Neurosurg Focus 25:E7
14. Rosner MJ, Becker DP (1984) Origin and evolution of plateau waves. Experimental observations and a theoretical model. J Neurosurg 60:312-324 (Pubitemid 14177708)
15. Santos E, Diedler J, Sykora M, Orakcioglu B, Kentar M, Czosnyka M, Unterberg A, Sakowitz OW (2011) Low-frequency sampling for PRx calculation does not reduce prognostication and produces similar CPPopt in intracerebral haemorrhage patients. Acta Neurochir 153:2189-2195
16. Santos E, Orakcioglu B, Kentar M, Diedler J, Uozumi Y, Schöll M Unterberg A, Sakowitz OW (2012) Pressure-related index of cerebrovascular reactivity correlates with metabolic dysfunction in a porcine model of intracerebral hemorrhage. In: Schuhmann M, Czosnyka M (eds) Intracranial pressure and brain monitoring XIV. Acta Neurochirurgica Supplementum, Springer-Verlag/Wien, pp 363-367
17. Sorrentino E, Diedler J, Kasprowicz M, Budohoski KP, Haubrich C, Smielewski P, Outtrim JG, Manktelow A, Hutchinson PJ, Pickard JD, Menon DK, Czosnyka M (2012) Critical thresholds for cerebrovascular reactivity after traumatic brain injury. Neurocrit Care 16:258-266
18. Steiner LA, Czosnyka M, Piechnik SK, Smielewski P, Chatfield D, Menon DK, Pickard JD (2002) Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Crit Care Med 30:733-738 (Pubitemid 34297786)
19. Strandgaard S, Paulson OB (1984) Cerebral autoregulation. Stroke 15:413-416 (Pubitemid 14105951)
20. Timofeev I, Carpenter KL, Nortje J, Al-Rawi PG, O'Connell MT, Czosnyka M, Smielewski P, Pickard JD, Menon DK, Kirkpatrick PJ, Gupta AK, Hutchinson PJ (2011) Cerebral extracellular chemistry and outcome following traumatic brain injury: A microdialysis study of 223 patients. Brain 134:484-494
21. Timofeev I, Czosnyka M, Carpenter KL, Nortje J, Kirkpatrick PJ, Al-Rawi PG, Menon DK, Pickard JD, Gupta AK, Hutchinson PJ (2011) Interaction between brain chemistry and physiology after traumatic brain injury: Impact of autoregulation and microdialysis catheter location. J Neurotrauma 28:849-860
22. Wang EC, Ang BT,Wong J, Lim J, Ng I (2006) Characterization of cerebrovascular reactivity after craniectomy for acute brain injury. Br J Neurosurg 20:24-30
23. White H, Venkatesh B (2008) Cerebral perfusion pressure in neurotrauma: A review. Anesth Analg 107:979-988
24. Zweifel C, Lavinio A, Steiner LA, Radolovich D, Smielewski P, Timofeev I, Hiler M, Balestreri M, Kirkpatrick PJ, Pickard JD, Hutchinson P, Czosnyka M (2008) Continuous monitoring of cerebrovascular pressure reactivity in patients with head injury. Neurosurg Focus 25:E2