Schistosoma mansoni schistosomula tegument (Smteg) immunization in absence of adjuvant induce IL-10 production by CD4+ cells and failed to protect mice against challenge infection

Acta Tropica

Volumn 124, Issue 2, 2012, Pages 140-146

  Araujo, Juliano Michel ^a   de Melo, Tatiane Teixeira ^a   de Sena, Isabela Campos ^a   Alves, Clarice Carvalho ^a   Araujo, Neusa ^a   Durães, Fernanda do Valle ^b   Oliveira, Sergio Costa ^b   Fonseca, Cristina Toscano ^a,c  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c Instituto Nacional de Ciencia e Tecnologia em Doencas Tropicais INCT DT   (Brazil)

Author keywords

Immunization; Regulatory response; Schistosoma mansoni; Schistosomula tegument

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; MICROBIAL PRODUCTS NOT CLASSIFIED ELSEWHERE;

ANTIBODY; CELL ORGANELLE; FECUNDITY; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNIZATION; MORBIDITY; PARASITE; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN PRESENTATION; ARTICLE; CD4 LYMPHOCYTE PERCENTAGE; CD4+ T LYMPHOCYTE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG TREATMENT FAILURE; FEMALE; FEMALE FERTILITY; IMMUNOMODULATION; INFECTION PREVENTION; INTEGUMENT; MALE; MORBIDITY; MOUSE; MYELOID DENDRITIC CELL; NONHUMAN; PARASITE LOAD; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SCHISTOSOMULUM; SPLEEN CELL; UPREGULATION;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; FERTILITY; HELMINTH PROTEINS; IMMUNIZATION; INTERFERON-GAMMA; INTERLEUKIN-10; MICE; MICE, INBRED C57BL; PARASITE LOAD; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; VACCINES;

MUS; SCHISTOSOMA MANSONI;

EID: 84865800048     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2012.07.007     Document Type: Article

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