Mesenchymal stromal cell neuroprotection of hydrogen peroxide -challenged pheochromocytoma cells through reducing apoptosis and releasing cytokines

Cytotherapy

Volumn 14, Issue 8, 2012, Pages 954-966

  Zhang, Yun ^a   Yang, Yaqing ^b   Bi, Yang ^a   Gong, Min ^a   Jiang, Wei ^a   Wei, Xiaoping ^a   Li, Tingyu ^a   Chen, Jie ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Apoptosis; Cytokines; Hydrogen peroxide; Hypoxicischemic insult; Marrow derived mesenchymal stromal cells; Pheochromocytoma cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; HYDROGEN PEROXIDE; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ASSAY; CELL DAMAGE; CELL LEVEL; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VIVO STUDY; MEMBRANE STEADY POTENTIAL; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 84865797860     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653249.2012.688946     Document Type: Article

References (42)

1. Calvert JW, Zhang JH. Pathophysiology of an hypoxic-ischemic insult during the perinatal period. Neurol Res. 2005;27:246-60.
2. Khot S, Tirschwell DL. Long-term neurological complications after hypoxic-ischemic encephalopathy. Semin Neurol. 2006;26:422-31.
3. Kristian T. Metabolic stages, mitochondria and calcium in hypoxic/ischemic brain damage. Cell Calcium. 2004;36:221-33.
4. Bi Y, Gong M, Zhang X, Zhang X, Jiang W, Zhang Y, et al. Pre-activation of retinoid signaling facilitates neuronal differentiation of mesenchymal stem cells. Dev Growth Differ. 2010;52:419-31.
5. Liu Y, Zhang X, Dai Y, Shu C, Qu P, Liu YX, et al. Effects of bone marrow mesenchymal stem cells on learning and memory functional recovery in neonatal rats with hypoxicischemic brain damage. Zhonghua Er Ke Za Zhi. 2008;46:648-53.
6. Phinney DG, Isakova I. Plasticity and therapeutic potential of mesenchymal stem cells in the nervous system. Curr Pharm Des. 2005;11:1255-65.
7. Prockop DJ. 'Stemness' does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs). Clin Pharmacol Ther. 2007;82:241-3.
8. Phinney DG, Prockop DJ. Concise review. Mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair, current views. Stem Cells. 2007;25:2896-902.
9. Marigo I, Dazzi F. The immunomodulatory properties of mesenchymal stem cells. Semin Immunopathol. 2011;33:593-602.
10. Ohtaki H, Ylostalo JH, Foraker JE, Robinson AP, Reger RL, Shioda S, et al. Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses. Proc Natl Acad Sci USA. 2008;105:14638-43.
11. van Velthoven CT, Kavelaars A, van Bel F, Heijnen CJ. Mesenchymal stem cell treatment after neonatal hypoxicischemic brain injury improves behavioral outcome and induces neuronal and oligodendrocyte regeneration. Brain Behav Immun. 2010;24:387-93.
12. Lee JA, Kim BI, Jo CH, Choi CW, Kim EK, Kim HS, et al. Mesenchymal stem-cell transplantation for hypoxic-ischemic brain injury in neonatal rat model. Pediatr Res. 2010;67:42-6.
13. Chen J, Ng CP, Rowlands DK, Xu PH, Gao JY, Chung YH, Chan HC. Interaction between enteric epithelial cells and Peyer's patch lymphocytes in response to Shigella lipopolysaccharide: effect on nitric oxide and IL-6 release. World J Gastroenterol 2006;12:3895-900.
14. Greene LA, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA. 1976;73:2424-8.
15. Ferriero DM. Oxidant mechanisms in neonatal hypoxiaischemia. Dev Neurosci. 2001;23:198-202.
16. Lafemina MJ, Sheldon RA, Ferriero DM. Acute hypoxiaischemia results in hydrogen peroxide accumulation in neonatal but not adult mouse brain. Pediatr Res. 2006;59:680-3.
17. Zhong C, Qin Z, Zhong CJ, Wang Y, Shen XY. Neuroprotective effects of bone marrow stromal cells on rat organotypic hippocampal slice culture model of cerebral ischemia. Neurosci Lett. 2003;342:93-6.
18. Bickler PE, Hansen BM. Causes of calcium accumulation in rat cortical brain slices during hypoxia and ischemia: role of ion channels and membrane damage. Brain Res. 1994;665:269-76.
19. Dos-Anjos S, Martinez-Villayandre B, Montori S, Perez-Garcia CC, Fernandez-Lopez A. Early modifications in N-methyl-D-aspartate receptor subunit mRNA levels in an oxygen and glucose deprivation model using rat hippocampal brain slices. Neuroscience. 2009;164:1119-26.
20. Matzinger P. The danger model: a renewed sense of self. Science. 2002;296:301-5.
21. Munoz JR, Stoutenger BR, Robinson AP, Spees JL, Prockop DJ. Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice. Proc Natl Acad Sci USA. 2005;102:18171-6.
22. Togel F, Hu Z, Weiss K, Isaac J, Lange C, Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005;289:F31-42.
23. Parr AM, Tator CH, Keating A. Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury. Bone Marrow Transplant. 2007;40:609-19.
24. Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem. 2006;98:1076-84.
25. Bischof J, Muller A, Fander M, Knippschild U, Fischer D. Neurite outgrowth of mature retinal ganglion cells and PC12 cells requires activity of CK1delta and CK1epsilon. PLOS ONE. 2011;6:e20857.
26. Harrill JA, Mundy WR. Quantitative assessment of neurite outgrowth in PC12 cells. Methods Mol Biol. 2011;758:331-48.
27. Li Q, Chau Y. Neural differentiation directed by self-assembling peptide scaffolds presenting laminin-derived epitopes. J Biomed Mater Res A. 2010;94:688-99.
28. Shaerzadeh F, Ahmadiani A, Esmaeili MA, Ansari N, Asadi S, Tusi SK, et al. Antioxidant and antiglycating activities of Salvia sahendica and its protective effect against oxidative stress in neuron-like PC12 cells. J Nat Med. 2011;65:455-65.
29. Tusi SK, Ansari N, Amini M, Amirabad AD, Shafiee A, Khodagholi F. Attenuation of NF-kappaB and activation of Nrf2 signaling by 1, 2, 4-triazine derivatives, protects neuron-like PC12 cells against apoptosis. Apoptosis. 2010;15:738-51.
30. Lafemina MJ, Sheldon RA, Ferriero DM. Acute hypoxiaischemia results in hydrogen peroxide accumulation in neonatal but not adult mouse brain. Pediatr Res. 2006;59:680-3.
31. Jeon GI, Yoon MY, Park HR, Lee SC, Park E. Neuroprotective activity of Viola mandshurica extracts on hydrogen peroxideinduced DNA damage and cell death in PC12 cells. Ann NY Acad Sci. 2009;1171:576-82.
32. Liu S, Han Y, Zhang T, Yang Z. Protective effect of trifluoperazine on hydrogen peroxide-induced apoptosis in PC12 cells. Brain Res Bull. 2011;84:183-8.
33. 2-induced apoptosis in PC12 cells. Biochem Biophys Res Commun. 2010;393:773-8.
34. Vannucci RC, Brucklacher RM, Vannucci SJ. Intracellular calcium accumulation during the evolution of hypoxicischemic brain damage in the immature rat. Brain Res Dev Brain Res. 2001;126:117-20.
35. 2+ channels. Eur J Pharmacol. 2008;586:90-9.
36. 2+ mobilization by hypoxia-induced NO generation in rat brain striatal slices and human astrocytoma U-373 MG cells and its involvement in tissue damage. Eur J Neurosci. 2003;17:692-700.
37. 2+ influx upregulate calpain and induce apoptosis in PC12 cells. Brain Res. 2000;852:326-34.
38. Lanza C, Morando S, Voci A, Canesi L, Principato MC, Serpero LD, et al. Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo. J Neurochem. 2009;110:1674-84.
39. Ladage D, Brixius K, Steingen C, Mehlhorn U, Schwinger RH, Bloch W, et al. Mesenchymal stem cells induce endothelial activation via paracrine mechanisms. Endothelium. 2007;14:53-63.
40. Aravalli RN, Peterson PK, Lokensgard JR. Toll-like receptors in defense and damage of the central nervous system. J Neuroimmune Pharmacol. 2007;2:297-312.
41. Marsh BJ, Williams-Karnesky RL, Stenzel-Poore MP. Toll-like receptor signaling in endogenous neuroprotection and stroke. Neuroscience. 2009;158:1007-20.
42. Walker PA, Harting MT, Jimenez F, Shah SK, Pati S, Dash PK, et al. Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NFkappaB-mediated increase in interleukin-6 production. Stem Cells Dev. 2010;19:867-76.